公开(公告)号：WO2013086633A1

公开(公告)日：2013-06-20

申请号：PCT/CA2012/050891

申请日：2012-12-12

Applicant: IOGEN ENERGY CORPORATION

Inventor： DUFRESNE, Philippe J. ,  COLVILLE, Adam H. ,  FRYZUK, Barbara ,  GUDYNAITE-SAVITCH, Loreta ,  HINDLE, Christopher M.d. ,  PLOCH, Boguslaw ,  TOMASHEK, John J.

IPC: C12N1/14 ,  C12N15/31 ,  C12N15/79 ,  C12N9/14 ,  C12N9/24 ,  C12P1/02 ,  C12P19/00 ,  C12N15/55 ,  C12N15/56

CPC classification number: C12P19/14 ,  C07K14/37 ,  C07K14/38 ,  C12N1/14 ,  C12N9/14 ,  C12N9/24 ,  C12N9/2437 ,  C12P19/00 ,  C12P19/02

Abstract: The present invention provides an isolated fungal cell that is capable of producing one or more biomass-degrading enzymes and that exhibits increased or decreased expression or copy number of a polynucleotide encoding a PtaB-like protein. Also provided is a fermentation processes for producing one or more biomass-degrading enzymes comprising a fungal cells exhibiting increased or decreased expression or copy number of a polynucleotide encoding a PtaB-like protein. The biomass-degrading enzymes produced by the isolate fungal cell and fermentation processes of the present invention may be used in a process to produce soluble sugars from biomass.

Abstract translation: 本发明提供了能够产生一种或多种生物质降解酶并且表现出增加或减少编码PtaB样蛋白的多核苷酸的表达或拷贝数的分离的真菌细胞。 还提供了用于产生一种或多种生物降解酶的发酵方法，其包含显示增加或减少编码PtaB样蛋白质的多核苷酸的表达或拷贝数的真菌细胞。 通过本发明的分离真菌细胞产生的生物质降解酶和发酵方法可用于从生物质产生可溶性糖的方法中。