公开(公告)号：WO2014016749A2

公开(公告)日：2014-01-30

申请号：PCT/IB2013055955

申请日：2013-07-19

Applicant: KONINKL PHILIPS NV

Inventor： BHARAT SHYAM

IPC: A61N5/10

CPC classification number: A61N5/1071 ,  A61N5/1001 ,  A61N5/1007 ,  A61N5/1037 ,  A61N5/1039 ,  A61N5/1049 ,  A61N5/1064 ,  A61N2005/1055 ,  A61N2005/1057 ,  A61N2005/1058 ,  A61N2005/1072 ,  A61N2005/1074

Abstract: A system and method include a shape sensing enabled device (116) having at least one optical fiber (118). A source positioning module (124) is configured to receive optical signals from the at least one optical fiber within a structure and interpret the optical signals to provide motion information of treatment sources within the device. A dose determination module (130) is configured to provide one or more temporal bins representing a total treatment time. For each temporal bin, the dose determination module is configured to determine a dose received bya target area to be treated using the motion information of the treatment sources. The dose determination module is further configured to combine the dose received by the target area for each of the one or more temporal bins to determine a total dose received by the target area.

Abstract translation: 一种系统和方法包括具有至少一个光纤（118）的形状感测使能设备（116）。 源定位模块（124）被配置为从结构内的至少一根光纤接收光信号并且解释光信号以提供设备内的治疗源的运动信息。 剂量确定模块（130）被配置为提供表示总治疗时间的一个或多个时间仓。 对于每个时间仓，剂量确定模块被配置为使用治疗源的运动信息确定待治疗的目标区域接收到的剂量。 剂量确定模块进一步被配置为针对一个或多个时间仓中的每一个组合由目标区域接收到的剂量以确定由目标区域接收的总剂量。

公开(公告)号：WO2014087289A3

公开(公告)日：2014-08-21

申请号：PCT/IB2013060261

申请日：2013-11-20

Applicant: KONINKL PHILIPS NV ,  SUNNYBROOK HEALTH SCIENCES CT

Inventor： BHARAT SHYAM ,  KRUECKER JOCHEN ,  RAVI ANANTH ,  DEHGHAN MARVAST EHSAN

IPC: A61N5/10

CPC classification number: A61N5/1039 ,  A61B8/0841 ,  A61B34/20 ,  A61B90/39 ,  A61B2034/2051 ,  A61B2034/2061 ,  A61B2090/363 ,  A61B2090/3925 ,  A61B2090/3966 ,  A61B2560/0223 ,  A61N5/1001 ,  A61N5/1027 ,  A61N5/103 ,  A61N5/1075 ,  G06T7/337 ,  G06T7/70 ,  G06T7/80 ,  G06T7/97 ,  G06T2207/10132 ,  G06T2207/30081

Abstract: The invention relates to a calibration apparatus for calibrating a system for introducing an influencing element like a radiation source into an object, particularly for calibrating a brachytherapy system. First and second images show a longish introduction device (12) like a catheter and a tracking device (16) like an electromagnetically trackable guidewire inserted into the introduction device as far as possible,and the introduction device and a calibration element(46)having the same dimensions as the influencing element and being inserted into the introduction device as far as possible. A spatial relation between the tracking device and the calibration element is determined based on the images for calibrating the system. Knowing this spatial relation allows accurately determining an influencing plan like a brachytherapy treatment plan and accurately positioning the influencing element in accordance with the influencing plan, which in turn allows for a more accurate influencing of the object.

Abstract translation: 本发明涉及一种用于校准用于将诸如辐射源的影响元件引入到物体中的系统的校准装置，特别是用于校准近距离放射治疗系统。 第一图像和第二图像显示出尽可能插入到引入装置中的类似于导管和跟踪装置（16）的漫长导入装置（12），并且引入装置和校准元件（46）具有 与影响元件相同的尺寸并且尽可能地插入到引入装置中。 基于用于校准系统的图像来确定跟踪装置和校准元件之间的空间关系。 了解这种空间关系可以准确地确定影响方案，如近距离放射疗法治疗计划，并根据影响计划准确定位影响因素，从而进一步影响对象。

公开(公告)号：WO2015145300A3

公开(公告)日：2015-12-03

申请号：PCT/IB2015051924

申请日：2015-03-17

Applicant: KONINKL PHILIPS NV

Inventor： BHARAT SHYAM ,  DEHGHAN MARVAST EHSAN ,  KUNG CYNTHIA MING-FU ,  TAHMASEBI MARAGHOOSH AMIR MOHAMMAD ,  DALAL SANDEEP M ,  KRUECKER JOCHEN ,  BONILLAS VACA ANTONIO ,  STANTON DOUGLAS ALLEN

IPC: A61B17/34 ,  A61B19/00

CPC classification number: A61B34/20 ,  A61B5/062 ,  A61B17/3403 ,  A61B2017/00274 ,  A61B2017/00725 ,  A61B2017/3411 ,  A61B2034/2051 ,  A61B2560/0223 ,  A61N5/1001 ,  A61N5/1027 ,  A61N5/1075 ,  A61N2005/1012

Abstract: An electromagnetic ("EM") tracking configuration system employs an EM quality assurance ("EMQA") (30) and EM data coordination ("DC") system (70). For the EMQA system (30), an EM sensor block (40) includes EM sensor(s) (22) positioned and oriented to represent a simulated electromagnetic tracking of interventional tool(s) inserted through electromagnetic sensor block (40) into an anatomical region. As an EM field generator (20) generates an EM field (21) encircling EM sensor(s) (22), an EMQA workstation (50) tests an EM tracking accuracy of an insertion of the interventional tool(s) through the EM sensor block (40) into the anatomical region. For the EMDC system (70), as EM field generator (20) generates EM field (21) encircling a mechanical interaction of EM calibration tool(s) (80) with a grid (120) for guiding interventional tool(s) through gird (120) into an anatomical region, the electromagnetic data coordination workstation (90) establishes a coordination system for electromagnetically tracking an insertion of the interventional tool(s) through grid (120) into the anatomical region.

Abstract translation: 电磁（“EM”）跟踪配置系统采用EM质量保证（EMQA）（30）和EM数据协调（“DC”）系统（70）。 对于EMQA系统（30），EM传感器块（40）包括定位和定向的EM传感器（22），以将通过电磁传感器块（40）插入到解剖学中的介入工具的模拟电磁跟踪 地区。 作为EM场发生器（20）产生围绕EM传感器（22）的EM场（21），EMQA工作站（50）测试通过EM传感器插入介入工具的EM跟踪精度 块（40）进入解剖区域。 对于EMDC系统（70），当EM场发生器（20）产生环绕EM校准工具（80）与网格（120）的机械相互作用的EM场（21），用于通过网格引导介入工具 （120）进入解剖区域，所述电磁数据协调工作站（90）建立用于电磁跟踪通过网格（120）插入所述解剖区域的介入工具的协调系统。

公开(公告)号：WO2015092664A3

公开(公告)日：2015-09-24

申请号：PCT/IB2014066937

申请日：2014-12-16

Applicant: KONINKL PHILIPS NV

Inventor： DEHGHAN MARVAST EHSAN ,  BHARAT SHYAM ,  TAHMASEBI MARAGHOOSH AMIR MOHAMMAD ,  COLE GREGORY ,  KRUECKER JOCHEN

IPC: A61B8/00 ,  A61B8/12

CPC classification number: A61B8/4254 ,  A61B8/12 ,  A61B8/58 ,  A61B8/587

Abstract: An ultrasound calibration system employs a calibration phantom (20), an ultrasound probe (10) and a calibration workstation (40a). The calibration phantom (20) encloses a frame assembly (21) within a calibration coordinate system established by one or more phantom trackers. In operation, the ultrasound probe (10) acoustically scans an image of the frame assembly (21) within an image coordinate system relative to a scan coordinate system established by one or more probe trackers. The calibration workstation (40a) localizes the ultrasound probe (10) and the frame assembly image (11) within the calibration coordinate system and determines a calibration transformation matrix between the image coordinate system and the scan coordinate system from the localizations.

Abstract translation: 超声波校准系统使用校准体模（20），超声波探头（10）和校准工作站（40a）。 校准体模（20）将框架组件（21）包围在由一个或多个幻影跟踪器建立的校准坐标系统内。 在操作中，超声波探头（10）相对于由一个或多个探针跟踪器建立的扫描坐标系统在图像坐标系中声学地扫描框架组件（21）的图像。 校准工作站（40a）将超声波探头（10）和框架组件图像（11）定位在校准坐标系内，并且从本地化确定图像坐标系和扫描坐标系之间的校准变换矩阵。

公开(公告)号：WO2014013418A3

公开(公告)日：2014-03-06

申请号：PCT/IB2013055813

申请日：2013-07-15

Applicant: KONINKL PHILIPS NV

Inventor： BHARAT SHYAM ,  DEHGHAN MARVAST EHSAN ,  KRUECKER JOCHEN ,  KUNG CYNTHIA MING-FU

IPC: A61N5/10

CPC classification number: A61N5/1007 ,  A61B2034/2051 ,  A61B2034/2055 ,  A61B2090/378 ,  A61N5/1027 ,  A61N5/103 ,  A61N2005/1012 ,  A61N2005/1018

Abstract: The invention relates to a determination apparatus for determining the pose and shape of an introduction element like a catheter within a living being, wherein the introduction element (12) is adapted to be used by a brachytherapy apparatus for introducing a radiation source (10) close to a target object (11) to be treated. A position determination element (27) like guidewire (20) with an electromagnetic tracking element (16) is introduced into the introduction element (12) such that it is arranged at different locations within the introduction element (12), wherein the positions of the position determination element (27) within the introduction element (12) are determined. The determined positions are then acquired depending on the determined positions for determining the pose and shape of the introduction element within the living being. This can lead to a determination procedure with reduced user interaction, thereby simplifying the determination procedure for the user.

Abstract translation: 本发明涉及一种用于确定引导元件（如生物体内的导管）的姿态和形状的确定装置，其中引入元件（12）适于由近距离放射治疗装置使用，以将辐射源（10） 到要治疗的目标物体（11）。 将具有电磁跟踪元件（16）的类似导丝（20）的定位元件（27）引入导入元件（12）中，使得其被设置在导入元件（12）内的不同位置处，其中 确定引入元件（12）内的位置确定元件（27）。 然后根据确定的位置获取确定的位置，以确定生物体内引入元件的姿态和形状。 这可以导致用户交互减少的确定过程，从而简化用户的确定过程。

公开(公告)号：WO2015044872A3

公开(公告)日：2015-06-11

申请号：PCT/IB2014064792

申请日：2014-09-24

Applicant: KONINKL PHILIPS NV

Inventor： BOROCZKY LILLA ,  BHARAT SHYAM ,  REINER BRUCE

IPC: A61B5/055 ,  A61B5/00 ,  A61B6/00 ,  A61B6/03 ,  G01R33/54

CPC classification number: G06T7/0012 ,  A61B5/0037 ,  A61B5/055 ,  A61B5/7221 ,  A61B6/032 ,  A61B6/037 ,  A61B6/488 ,  A61B6/50 ,  A61B6/5258 ,  A61B6/5294 ,  A61B6/545 ,  G01R33/543 ,  G06T2207/10088 ,  G06T2207/30004 ,  G06T2207/30168

Abstract: A method generates images based on context-aware imaging. The method includes acquiring a first image of a patient using first image acquisition parameters. The method includes determining, within the first image, an area as a function of first data associated with the patient. The method includes determining modification data as a function of at least one of (a) second data corresponding to the determined area and (b) the first data. The method includes determining second image acquisition parameters as a function of the modification data and the first image acquisition parameters. The method includes acquiring a second image of the patient using the second image acquisition parameters.

Abstract translation: 一种方法基于上下文感知成像生成图像。 该方法包括使用第一图像获取参数来获取患者的第一图像。 该方法包括在第一图像内确定作为与患者相关联的第一数据的函数的区域。 该方法包括将修改数据确定为（a）对应于所确定的区域的第二数据和（b）第一数据中的至少一个的函数。 该方法包括根据修改数据和第一图像获取参数来确定第二图像采集参数。 该方法包括使用第二图像采集参数获取患者的第二图像。

公开(公告)号：WO2015011690A3

公开(公告)日：2015-04-23

申请号：PCT/IB2014063435

申请日：2014-07-25

Applicant: KONINKL PHILIPS NV

Inventor： BHARAT SHYAM ,  DEHGHAN MARVAST EHSAN ,  FOKKENROOD STEVEN ANTONIE WILLEM

IPC: A61B8/00

CPC classification number: A61B8/00 ,  A61B8/12 ,  A61B8/4245 ,  A61B8/4494 ,  A61B8/5223 ,  A61B8/5253 ,  A61B2017/00274 ,  A61B2018/00547 ,  A61N5/1027 ,  A61N2005/1058

Abstract: The invention relates to an imaging system for generating an image of a living object (11) like an image from a prostate during a brachytherapy. A first ultrasound data generating unit (40) like a TRUS probe generates first ultrasound data of a field of view (52) including the object and a second ultrasound data generating unit (50), which might be an ultrasound transducer on a brachytherapy catheter (12), generates second ultrasound data of at least a part of the field of view, wherein a segmented ultrasound image, in which the object is segmented, is generated based on the ultrasound data. In particular, spatial regions, which are not sensible by the first ultrasound data generating unit due to shadows (53), may be sensible by the second ultrasound data generating unit, which may allow for an augmentation of the first ultrasound data and finally for a segmented image having an improved quality.

Abstract translation: 本发明涉及一种用于在近距离放射治疗期间产生像来自前列腺的图像的活体（11）的图像的成像系统。 如TRUS探针的第一超声数据生成单元（40）产生包括物体的视场（52）的第一超声数据和第二超声数据生成单元（50），其可以是近距离放射治疗导管上的超声换能器 生成视场的至少一部分的第二超声数据，其中基于超声数据生成分割对象的分割超声图像。 特别地，第二超声数据生成单元，由于阴影（53）而不由第一超声数据生成单元不敏感的空间区域可能是可能的，这可以允许增加第一超声数据， 分割图像具有改进的质量。

公开(公告)号：WO2013080165A3

公开(公告)日：2013-08-01

申请号：PCT/IB2012056851

申请日：2012-11-30

Applicant: KONINKL PHILIPS NV ,  UNIV ST LOUIS

Inventor： BHARAT SHYAM ,  BAL MATTHIEU FREDERIC ,  PARIKH PARAG JITENDRA ,  MOORE KEVIN LAWRENCE

IPC: G06F19/00

CPC classification number: G06F19/3487 ,  A61N5/103 ,  G06F19/322 ,  G06F19/3481 ,  G06Q50/22 ,  G16H10/60 ,  G16H15/00

Abstract: A method for reviewing a treatment plan including displaying list of at least one of a selected plurality of patients, institutions, and treatment plans associated with a treatment planning system, selecting at least one of the one or more patients, institutions, and treatment plans, querying treatment plan parameters associated with the selected one or more patients, institutions, and treatment plans, and generating a report file of the queried treatment plan parameters

Abstract translation: 一种用于查看治疗计划的方法，该方法包括显示与治疗计划系统相关联的选定的多个患者，机构和治疗计划中的至少一个的列表，选择一个或多个患者，机构和治疗计划中的至少一个， 查询与所选择的一个或多个患者，机构和治疗计划相关联的治疗计划参数，并且生成所查询的治疗计划参数的报告文件