公开(公告)号：WO2015184270A1

公开(公告)日：2015-12-03

申请号：PCT/US2015/033203

申请日：2015-05-29

Applicant: LI, Xiujun ,  DOU, Maowei

Inventor： LI, Xiujun ,  DOU, Maowei

IPC: G01N33/53

CPC classification number: G01N33/54386 ,  B01L3/5023 ,  B01L3/5027 ,  B01L2200/10 ,  B01L2300/0636 ,  B01L2300/0681 ,  B01L2300/069 ,  B01L2300/0803 ,  B01L2300/0864 ,  B01L2300/126 ,  B01L2400/0409 ,  C12Q1/689 ,  G01N33/56911 ,  G01N2333/22 ,  G01N2333/255 ,  G01N2333/31 ,  G01N2333/3156 ,  G01N2333/335

Abstract: Certain embodiments are directed to paper/polymer hybrid microfluidic devices integrated with nano-biosensors for pathogen detection and infectious disease diagnosis. Microfluidics provides for minimal reagent consumption, integrated processing, and analysis of complex biological fluids with high efficiency and sensitivity. The devices and methods described herein provide for simple, rapid, and sensitive pathogen detection at low cost. Embodiments include methods and devices for direct pathogen detection.

Abstract translation: 某些实施方案涉及与用于病原体检测和感染性疾病诊断的纳米生物传感器集成的纸/聚合物杂交微流体装置。 微流体提供了最低的试剂消耗，综合处理和复杂生物流体的分析，具有高效率和灵敏度。 本文所述的装置和方法以低成本提供简单，快速和敏感的病原体检测。 实施方案包括用于直接病原体检测的方法和装置。

公开(公告)号：WO2016007819A1

公开(公告)日：2016-01-14

申请号：PCT/US2015/039878

申请日：2015-07-10

Applicant: LI, XiuJun ,  DOU, Maowei ,  DOMINGUEZ, Delfina

Inventor： LI, XiuJun ,  DOU, Maowei ,  DOMINGUEZ, Delfina

IPC: G01N21/00 ,  C12M1/34 ,  G01N21/75

CPC classification number: B01L3/50851 ,  B01L3/5027 ,  B01L3/502715 ,  B01L7/52 ,  B01L2200/0605 ,  B01L2300/0636 ,  B01L2300/0681 ,  B01L2300/0816 ,  B01L2300/0864 ,  B01L2300/0867 ,  B01L2300/0887 ,  B01L2300/0893 ,  B01L2300/126 ,  C12Q1/6865 ,  C12Q1/6867 ,  C12Q1/689 ,  C12Q2563/107 ,  C12Q2565/601 ,  C12Q2565/629

Abstract: Certain embodiments are directed to paper and its hybrid microfluidic devices integrated with nucleic acid amplification for simple, cost-effective, rapid, and sensitive pathogen detection, especially in low-resource settings.

Abstract translation: 某些实施方案涉及与用于简单，成本效益，快速和敏感的病原体检测的核酸扩增整合的纸及其杂交微流体装置，特别是在低资源设置中。