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1.发明申请PERCUTANEOUSLY-DEPLOYABLE PROSTHETIC TRICUSPID VALVE 审中-公开PERCUTANEOUSOOLY-DEPLOYABLE PROSTHETIC TRICUSPID VALVE
公开(公告)号：WO2016186909A1
公开(公告)日：2016-11-24
申请号：PCT/US2016/031730
申请日：2016-05-11
Inventor： POLLAK, Peter M.
IPC: A61F2/24
CPC classification number: A61F2/2418 , A61F2/2412 , A61F2/2439 , A61F2230/0067
Abstract: Devices and methods for the treatment of heart conditions are provided herein. For example, this document provides devices and methods for treating tricuspid valve regurgitation by percutaneously implanting a prosthetic tricuspid valve. The prosthetic tricuspid valve includes a structural framework with one or more braided nitinol wires, the structural framework has an outer surface and an inner open region, a cuff disposed on a proximal end portion of the outer surface, a flexible material covering the cuff, tissue piercing anchor features extending outward from the outer surface, and a valve assembly within the inner open region, the valve assembly having three leaflets that coaptate with each other. The valve is reconfigurable between a low-profile delivery configuration for containment within a delivery catheter and an expanded deployed configuration.
Abstract translation: 本文提供了用于治疗心脏病症的装置和方法。 例如，本文件提供通过经皮植入假体三尖瓣治疗三尖瓣反流的装置和方法。 假体三尖瓣包括具有一个或多个编织镍钛诺丝的结构框架，该结构框架具有外表面和内部开放区域，设置在外表面的近端部分上的袖带，覆盖袖带的柔性材料，组织 从外表面向外延伸的穿刺锚固件，以及在内部开放区域内的阀组件，该阀组件具有三个彼此接合的传单。 阀可重配置在用于在输送导管内容纳的低轮廓输送配置和扩展的部署配置之间。
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2.发明申请A NOVEL CONCEPT TO REDUCE LEFT ATRIAL PRESSURE IN SYSTOLIC AND DIASTOLIC HF PATIENTS TO TREAT PULMONARY EDEMA AND REDUCE HOSPITALIZATION RATES 审中-公开一个新的概念，减少左心室压力在同步和脱水HF患者治疗肺动脉高压和降低医院率
公开(公告)号：WO2016126921A1
公开(公告)日：2016-08-11
申请号：PCT/US2016/016532
申请日：2016-02-04
Inventor： ANAND, Umang , GOEL, Raghav , MCGOWAN, Roger , ROSS, Daniel , HAVERKOST, Patrick , BYRON, Mary , WULFMAN, David R. , ROHL, James , POLLAK, Peter M. , OLSON, Lyle , BEHFAR, Atta , BRUCE, Charles
CPC classification number: A61B17/0057 , A61B2017/00575 , A61B2017/00592 , A61B2017/00597 , A61B2017/00606 , A61B2017/00623 , A61F2/24 , A61F2210/0014 , A61F2230/0069
Abstract: Devices provided herein can include implantable transseptal flow control components adapted to be implanted in an opening in a septal wall. In a closed configuration, the implantable transseptal flow control components provided herein prevent blood from flowing through the opening. In an open configuration, the implantable transseptal flow control components provided herein allow blood to flow from the left atrium to the right atrium. In a closed configuration, implantable transseptal flow control components provided herein can be configured such that blood does not stagnate at a location proximate to a left atrium flow control component side when the pressure differential is below a second predetermined threshold pressure value. Implantable transseptal flow control components provided herein can remain in a closed configuration when a pressure differential between the left atrium and the right atrium is less than a first non-zero predetermined threshold pressure value.
Abstract translation: 本文提供的装置可包括适于植入隔壁中的开口的可植入经血流控制部件。 在闭合构造中，本文提供的可植入经血流控制组件防止血液流过开口。 在开放构型中，本文提供的可植入经血流控制组件允许血液从左心房流向右心房。 在闭合构造中，本文提供的可植入经血流控制部件可被构造成使得当压力差低于第二预定阈值压力值时，血液不会滞留在靠近左心房流量控制部件侧的位置处。 当左心房和右心房之间的压力差小于第一非零预定阈值压力值时，本文提供的可植入经血流量控制组件可以保持在闭合配置。
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公开(公告)号：WO2017106713A1
公开(公告)日：2017-06-22
申请号：PCT/US2016/067275
申请日：2016-12-16
Inventor： ROHL, James P. , BYRON, Mary M. , WULFMAN, David R. , CAWTHRA, JR., James K. , ARNHOLT, Devon N. , EPPIHIMER, Michael , LEHSE, David J. , BALDWIN, Katherine Lorraine , DEARANI, Joseph A. , POLLAK, Peter M.
CPC classification number: A61B17/1227 , A61B17/1285 , A61B2017/00247 , A61B2017/00592 , A61B2017/00606 , A61B2017/00623 , A61B2017/00783 , A61B2017/00867 , A61B2017/0409 , A61B2017/0419 , A61B2017/0464 , A61F2/2487 , A61F2230/001 , A61F2230/0071
Abstract: A heart valve anchor has a body that includes a distal portion, a distal end, a proximal portion, and a proximal end. The distal end and the proximal end define a longitudinal axis. The body has an expandable portion that includes a first radially expandable portion at the distal portion of the body, a second radially expandable portion at the proximal portion of the body, and a root portion disposed between the first and second radially expandable portions. The body has a first configuration adapted to be housed at least partially within a tissue penetrating device, and a second configuration in which the first and second radially expandable portions are partially or fully expanded such that the anchor engages tissue in a region between the first and second radially expandable portions.
Abstract translation: 心脏瓣膜锚定件具有包括远侧部分，远侧端部，近侧部分和近侧端部的主体。 远端和近端限定纵向轴线。 该主体具有可扩张部分，该可扩张部分包括在主体的远侧部分处的第一径向可扩展部分，在主体的近侧部分处的第二径向可扩展部分以及布置在第一和第二径向可扩展部分之间的根部部分。 主体具有适于至少部分地容纳在组织穿透装置内的第一构造和其中第一和第二径向可扩展部分部分或完全扩张的第二构造，使得锚固件接合第一和第二径向可扩张部分之间的区域中的组织 第二径向可扩展部分。
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公开(公告)号：WO2016187262A1
公开(公告)日：2016-11-24
申请号：PCT/US2016/033008
申请日：2016-05-18
Inventor： POLLAK, Peter M.
CPC classification number: A61B8/12 , A61B8/0841 , A61B8/0883 , A61B8/445 , A61B17/00 , A61B17/3478 , A61B34/73 , A61B2017/00247 , A61B2017/00477 , A61B2017/3413 , A61B2034/2063 , A61M25/00 , A61M25/01
Abstract: This document provides devices and methods for interventional treatment of heart conditions. For example, this document provides devices and methods that enhance intra-cardiac echocardiography visualization of interventional devices such as trans-septal puncturing needles.
Abstract translation: 本文档提供介入治疗心脏病症的手段和方法。 例如，本文件提供了增强介入装置的心脏内超声心动图可视化的装置和方法，例如反间隔穿刺针。
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公开(公告)号：WO2016186909A8
公开(公告)日：2016-11-24
申请号：PCT/US2016/031730
申请日：2016-05-11
Inventor： POLLAK, Peter M.
IPC: A61F2/24
Abstract: Devices and methods for the treatment of heart conditions are provided herein. For example, this document provides devices and methods for treating tricuspid valve regurgitation by percutaneously implanting a prosthetic tricuspid valve. The prosthetic tricuspid valve includes a structural framework with one or more braided nitinol wires, the structural framework as an outer surface and an inner open region, a cuff disposed on a proximal end portion of the outer space, a flexible material covering the cuff, tissue piercing anchor features extending outward from the outer surface, and a valve assembly within the inner open region, the valve assembly having three leaflets that coaptate with each other. The valve is reconfigurable between a low-profile delivery configuration for containment within a delivery catheter and an expanded deployed configuration.
Abstract translation: 本文提供了用于治疗心脏病的装置和方法。 例如，该文件提供了通过经皮植入假体三尖瓣来治疗三尖瓣返流的装置和方法。 假体三尖瓣包括具有一个或多个编织镍钛诺线的结构框架，作为外表面和内部开放区域的结构框架，设置在外部空间的近端部分上的套囊，覆盖套囊的柔性材料，组织 从外表面向外延伸的刺穿锚定件以及内部敞开区域内的阀组件，该阀组件具有三个彼此紧固的小叶。 该阀门可在配置在输送导管内的低剖面输送配置和扩展的展开配置之间进行重新配置。
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Patent Agency Ranking
公开(公告)号：WO2015031304A1
公开(公告)日：2015-03-05
申请号：PCT/US2014/052616
申请日：2014-08-26
Inventor： POLLAK, Peter M.
CPC classification number: A61F2/2427 , A61F2/2403 , A61F2/2409 , A61F2/2412 , A61F2/2415 , A61F2/2433 , A61F2/2445 , A61F2230/0069 , A61F2230/0091 , A61F2250/006
Abstract: Devices and methods for the treatment of heart conditions. For example, a prosthetic heart valve and a transcatheter heart valve replacement method. The prosthetic heart valve can be configured into a low-profile configuration for containment within a small diameter delivery sheath.
Abstract translation: 用于治疗心脏病症的装置和方法。 例如，假体心脏瓣膜和经导管心脏瓣膜置换方法。 假体心脏瓣膜可以被配置成一个小型构型，用于容纳在小直径输送护套内。
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公开(公告)号：WO2019168968A1
公开(公告)日：2019-09-06
申请号：PCT/US2019/019813
申请日：2019-02-27
Applicant: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH , POLLAK, Peter M. , ASIRVATHAM, Samuel J. , BRUCE, Charles J. , FRIEDMAN, Paul A. , VENKATACHALAM, Kalpathi L.
Inventor： POLLAK, Peter M. , ASIRVATHAM, Samuel J. , BRUCE, Charles J. , FRIEDMAN, Paul A. , VENKATACHALAM, Kalpathi L.
Abstract: Devices and methods for the treatment of heart conditions, and other medical purposes, include cardiac pacing systems. For example, this document describes temporary transvenous endocardial pacemaker systems and devices for deploying such systems without the need for conventional imaging procedures.
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公开(公告)号：WO2019050937A1
公开(公告)日：2019-03-14
申请号：PCT/US2018/049531
申请日：2018-09-05
Inventor： POLLAK, Peter M. , WALLACE, Michael B. , BRUCE, Charles J.
IPC: A61B5/00 , A61B5/02 , A61B5/0402
CPC classification number: A61B5/0053 , A61B5/02133 , A61B5/0215 , A61B5/687
Abstract: Devices described herein can be used to directly measure left atrial pressure. For example, this document describes multiple embodiments of catheter-based, trans-esophageal tonometry devices that are used to directly measure left atrial pressure in a non-invasive manner.
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9.发明申请
公开(公告)号：WO2017106720A1
公开(公告)日：2017-06-22
申请号：PCT/US2016/067285
申请日：2016-12-16
Inventor： ROHL, James P. , LEHSE, David J. , ARNHOLT, Devon N. , HORRISBERGER, Benn , EGGERT, Joel T. , POLLAK, Peter M. , DEARANI, Joseph A. , BALDWIN, Katherine Lorraine
CPC classification number: A61B90/361 , A61B1/00098 , A61B17/1285 , A61B2017/00247 , A61B2017/0409 , A61B2017/0464
Abstract: An introducer catheter device comprising a handle and an elongate shaft coupled to the handle and extending therefrom. The shaft defines a lumen therethrough, a longitudinal axis, and a first aperture in connection with the lumen. The shaft includes a movable deployment element configured for deploying an ancillary device from the first aperture at an angle relative to the longitudinal axis.
Abstract translation: 引导器导管装置包括手柄和联接到手柄并从手柄延伸的细长轴。 该轴限定穿过其中的内腔，纵向轴线以及与内腔相连的第一孔。 所述轴包括可移动展开元件，所述可移动展开元件构造成用于相对于所述纵向轴线以一定角度从所述第一孔展开辅助装置。
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公开(公告)号：WO2016118875A1
公开(公告)日：2016-07-28
申请号：PCT/US2016/014546
申请日：2016-01-22
Inventor： ROHL, James P. , WULFMAN, David R. , BERG, Brian T. , DELANEY, Joseph, Thomas, Jr. , TISCHLER, Brian J. , POLLAK, Peter M. , BURKHART, Harold M. , DEARANI, Joseph, A. , PISLARU, Sorin, V.
CPC classification number: A61B1/00082 , A61B1/00087 , A61B1/00147 , A61B1/018 , A61B1/05 , A61B1/0676 , A61B1/3137 , A61B8/12 , A61B17/0401 , A61B17/0469 , A61B17/0644 , A61B17/068 , A61B17/122 , A61B17/1227 , A61B17/1285 , A61B2017/00526 , A61B2017/00783 , A61B2017/00902 , A61B2017/00907 , A61B2017/0406 , A61B2017/0409 , A61B2017/0472 , A61B2017/048 , A61B2017/06042 , A61B2017/0649 , A61B2090/306 , A61B2090/309 , A61B2090/3612 , A61F2220/0008 , A61F2220/0016 , A61M25/1002 , A61M25/1029 , A61M2025/105 , A61M2025/1075 , A61M2025/1088
Abstract: A direct visualization catheter includes an elongate shaft defining a lumen and having a distal end portion and a proximal end portion and a transparent balloon attached to the distal end portion of the shaft. The balloon includes a first layer comprising a thermoset polymer and a plurality of polymeric fibers at least partially embedded in the thermoset polymer and a second layer disposed on the first layer and comprising a hydrogel.
Abstract translation: 直接可视导管包括限定内腔的细长轴，并且具有远端部分和近端部分以及附接到轴的远端部分的透明囊。 气囊包括包含热固性聚合物和至少部分地嵌入热固性聚合物中的多个聚合物纤维的第一层和设置在第一层上并包含水凝胶的第二层。
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