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公开(公告)号：WO2017218477A1
公开(公告)日：2017-12-21
申请号：PCT/US2017/037161
申请日：2017-06-13
申请人： MUFFIN INCORPORATED
发明人： HAVEL, William, J. , SISKEN, Richard, B. , FEARNOT, Neal, E. , BUHRMESTER, Marc, C. , JONES, James, T.
CPC分类号： B65B55/12 , B65B3/003 , B65B39/00 , B65B55/02 , B65B55/025
摘要： Among other things, there is shown a system for filling vials with fluid that maintains a localized sterile zone around the filling location. In particular embodiments, the sterile zone is provided by a manifold having an internal space to which clean air is supplied. One or more filling assemblies are attached to the manifold. Vials enter the sterile zone and are filled within it. Additional structure, such as coverings for vials, are disclosed to assist in maintaining sterility.
摘要翻译： 除其他之外，显示了用液体填充小瓶的系统，其在填充位置周围保持局部无菌区域。 在特定实施例中，无菌区由具有供应清洁空气的内部空间的歧管提供。 一个或多个填充组件连接到歧管。 小瓶进入无菌区并填充在其中。 额外的结构，如小瓶盖，被披露，以协助保持无菌。
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公开(公告)号：WO2014149977A1
公开(公告)日：2014-09-25
申请号：PCT/US2014/021699
申请日：2014-03-07
申请人： MUFFIN INCORPORATED
CPC分类号： A61M5/34 , A61B18/24 , A61M5/1582 , A61M25/0069 , A61M25/007
摘要： Methods and apparatus are provided for treating tissue with apparatus that includes an priming portion for initiating a healing response in the tissue to be treated, and which delivers a bioactive agent during or after preparing tissue adjacent the apparatus, as by generating or aiding a healing, regeneration or repair response in the tissue. The priming portion may comprise an abrasive surface, fluid ejection ports, and/or stimulation by electrical, thermal, or light energy.
摘要翻译： 提供了用于处理组织的方法和装置，所述装置包括用于在待治疗的组织中起始愈合反应的引发部分，并且在制备邻近所述装置的组织中或之后递送生物活性剂，如通过产生或辅助愈合， 在组织中的再生或修复反应。 起动部分可以包括研磨表面，流体喷射口，和/或通过电，热或光能的刺激。
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公开(公告)号：WO2017059284A1
公开(公告)日：2017-04-06
申请号：PCT/US2016/054851
申请日：2016-09-30
申请人： MUFFIN INCORPORATED
发明人： SISKEN, Richard, B. , JONES, James, Thomas , BAXTER, Charles, Leland , BUHRMESTER, Marc, C. , HAVEL, William, J. , PURDY, James, D. , FEARNOT, Neal, E. , AMICK, Kyle, D.
CPC分类号： B65B3/003 , A61J1/067 , B65B3/04 , B65B7/02 , B65B7/161 , B65B39/04 , B65B39/12 , B65B51/10 , B65B51/142
摘要： A filling and sealing system is provided for efficiently filling a series of individual vials with therapeutic liquids. In particular embodiments, the system includes a filling zone or station, a sealing zone or station, an unloading zone or station, and electronic controls.
摘要翻译： 提供了一种填充和密封系统，用于有效地填充具有治疗液体的一系列单独的小瓶。 在具体实施例中，系统包括填充区或站，密封区或站，卸载区或站以及电子控制。
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公开(公告)号：WO2016033135A1
公开(公告)日：2016-03-03
申请号：PCT/US2015/046848
申请日：2015-08-26
申请人： MUFFIN INCORPORATED
发明人： HAVEL, William, J. , FEARNOT, Neal, E. , MCKINNIS, Peter, S. , SISKEN, Richard, B. , BAXTER, Charles, Leland
CPC分类号： A61J1/1406 , A61J1/10 , A61J1/1468 , A61J1/2093 , B29C65/02 , B29C65/04 , B29C65/08 , B29C65/10 , B29C65/14 , B29C65/16 , B29C65/48 , B29C65/4895 , B29C66/1122 , B29C66/344 , B29C66/3452 , B29C66/43121 , B29C66/71 , B29C66/7212 , B29C66/73921 , B29C66/8266 , B29C66/8322 , B29L2031/7148 , B31B70/00 , B65B51/26 , B65D75/42 , B65D75/44 , B65D75/5883 , B29K2023/083 , B29K2307/04 , B29K2023/06 , B29K2023/12 , B29K2027/06 , B29K2075/00
摘要： Described in one aspect is a multi-cell or multi-chambered container for sealing various materials such as therapeutic or diagnostic agents, animal or human tissue, tissue samples, specimens, blood, genetic material, or any other material. The container includes seals formed by folding the wall of the elongate body transverse to the interior of the elongate body and maintaining the folded wall portions adjacent one another or joining them together. In another aspect, the container disclosed may be made according to a method involving creating multiple seals at various locations along the elongate body thus creating sealed voids or cells between the seals within the elongate body.
摘要翻译： 一方面描述了用于密封诸如治疗或诊断剂，动物或人体组织，组织样品，标本，血液，遗传物质或任何其它材料的各种材料的多细胞或多室容器。 容器包括通过将细长体的壁横向于细长主体的内部折叠并将折叠的壁部分彼此相邻或将它们连接在一起而形成的密封件。 在另一方面，所公开的容器可以根据涉及在沿细长体的不同位置产生多个密封件的方法制造，从而在细长体内的密封件之间形成密封的空隙或细胞。
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