公开(公告)号：WO2006072249A1

公开(公告)日：2006-07-13

申请号：PCT/DK2006/000006

申请日：2006-01-05

Applicant: NOVOZYMES A/S ,  MYGIND, Per, Holse ,  OLSEN, Peter, Bjarke

Inventor： MYGIND, Per, Holse ,  OLSEN, Peter, Bjarke

IPC: C12N5/10 ,  C12N15/12 ,  C12N15/82 ,  C07K14/00 ,  A61K38/16

CPC classification number: C07K14/00 ,  A61K38/00 ,  C12N2799/021

Abstract: The present invention relates to isolated polypeptides having antimicrobial activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.

公开(公告)号：WO2003087142A2

公开(公告)日：2003-10-23

申请号：PCT/DK2003/000199

申请日：2003-03-25

Applicant: NOVOZYMES A/S ,  ANDERSEN, Jens, Tønne ,  JØRGENSEN, Steen, Troels ,  RASMUSSEN, Michael, Dolbjerg ,  OLSEN, Peter, Bjarke ,  CLAUSEN, Ib, Groth

Inventor： ANDERSEN, Jens, Tønne ,  JØRGENSEN, Steen, Troels ,  RASMUSSEN, Michael, Dolbjerg ,  OLSEN, Peter, Bjarke ,  CLAUSEN, Ib, Groth

IPC: C07K14/195

CPC classification number: C07K14/32 ,  C12N9/00

Abstract: A Bacillus licheniformis mutant host cell derived from a parent B. licheniformis host cell, which mutant host cell is mutated in one or more gene(s) encoding one or more polypeptide(s) involved in antibiotic synthesis which is at least 80% identical to one or more of the polypeptides shown in SEQ ID NO's: 2 to 22, wherein the mutant host cell expresses at least 5% less of the one or more polypeptide(s) involved in antibiotic synthesis than the parent host cell, when they are cultivated under comparable conditions.

Abstract translation: 衍生自亲本地衣芽孢杆菌宿主细胞的地衣芽孢杆菌突变宿主细胞，所述突变宿主细胞在一个或多个编码涉及抗生素合成的一种或多种多肽的基因中突变，所述多个基因与至少80％ SEQ ID NO：2至22中所示的一种或多种多肽，其中当培养它们时，突变宿主细胞表达比亲本宿主细胞参与抗生素合成的一种或多种多肽的至少5％ 在可比条件下。

公开(公告)号：WO2018206001A1

公开(公告)日：2018-11-15

申请号：PCT/CN2018/086528

申请日：2018-05-11

Applicant: NOVOZYMES A/S ,  LIU, Ye

Inventor： LIU, Ye ,  LI, Ming ,  SCHNORR, Kirk Matthew ,  OLSEN, Peter, Bjarke

IPC: C12N15/56 ,  C07K14/37

Abstract: Animal feed or animal feed additives comprising one or more polypeptides having lysozyme activity. Polypeptides having lysozyme activity, polynucleotides encoding the polypeptides nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.

公开(公告)号：WO2017001701A1

公开(公告)日：2017-01-05

申请号：PCT/EP2016/065682

申请日：2016-07-04

Applicant: NOVOZYMES A/S ,  DSM IP ASSETS B.V.

Inventor： SANDVANG, Dorthe, Hoej ,  GAD, Esben ,  KELLY, Nicholas, Michael ,  KLAUSEN, Mikkel ,  THOEGERSEN, Juliane, Charlotte, Gregaard ,  OLSEN, Peter, Bjarke ,  NIELSEN, Preben ,  COHN, Marianne, Thorup

IPC: A23K10/10 ,  A23K20/147

CPC classification number: A23K20/189 ,  A61K9/0053 ,  A61K38/465 ,  A61K38/47 ,  C12Y301/03026 ,  C12Y302/01017 ,  A61K2300/00

Abstract: The present invention relates to animal feed compositions comprising polypeptides having lysozyme activity and polypeptides having phytase activity and uses thereof.

Abstract translation: 本发明涉及包含具有溶菌酶活性的多肽和具有植酸酶活性的多肽的动物饲料组合物及其应用。

公开(公告)号：WO2014102180A1

公开(公告)日：2014-07-03

申请号：PCT/EP2013/077638

申请日：2013-12-20

Applicant: NOVOZYMES A/S

Inventor： CHRISTENSEN, Bjarke ,  OLSEN, Peter, Bjarke ,  REGUEIRA, Torsten, Bak ,  KOEBMANN, Brian ,  JOERGENSEN, Steen, Troels ,  DEHLI, Tore, Ibsen

IPC: C12P7/04 ,  C12N9/88 ,  C12N9/90

CPC classification number: C12N9/88 ,  C12N9/1029 ,  C12N9/13 ,  C12N9/90 ,  C12P7/04 ,  C12Y203/0301 ,  C12Y401/03004 ,  C12Y402/03003

Abstract: Provided herein are recombinant Lactobacillus reuteri host cells comprising a heterologous polynucleotide encoding a methylglyoxal synthase, optionally with a heterologous polynucleotides encoding a triosephosphate isomerase. Also described are methods of using the recombinant Lactobacillus reuteri host cells to produce propanol and propylene.

Abstract translation: 本文提供了重组的罗伊氏乳杆菌宿主细胞，其包含编码甲基乙二醛合酶的异源多核苷酸，任选地与编码三磷酸异构酶的异源多核苷酸。 还描述了使用重组的赖氨酸乳杆菌宿主细胞产生丙醇和丙烯的方法。

公开(公告)号：WO2003087148A3

公开(公告)日：2003-10-23

申请号：PCT/DK2003/000200

申请日：2003-03-25

Applicant: NOVOZYMES A/S ,  ANDERSEN, Jens, Tønne ,  JØRGENSEN, Steen, Troels ,  RASMUSSEN, Michael, Dolbjerg ,  OLSEN, Peter, Bjarke ,  CLAUSEN, Ib, Groth

Inventor： ANDERSEN, Jens, Tønne ,  JØRGENSEN, Steen, Troels ,  RASMUSSEN, Michael, Dolbjerg ,  OLSEN, Peter, Bjarke ,  CLAUSEN, Ib, Groth

IPC: C12N15/75

Abstract: A Bacillus licheniformis mutant host cell comprising a mutation (deletion) in one or more genes encoding polypeptides involved in sporulation wherein the mutant host cell expresses at least 5% less of the one or more polypeptides involved in sporulation than the parent host cell, when cultivated under comparable conditions. The mutant host cell is used for producing heterologous polypeptides.

公开(公告)号：WO2018113743A1

公开(公告)日：2018-06-28

申请号：PCT/CN2017/117753

申请日：2017-12-21

Applicant: NOVOZYMES A/S ,  LIU, Ye

Inventor： LIU, Ye ,  KLAUSEN, Mikkel ,  SCHNORR, Kirk Matthew ,  SKOV, Lars Kobberoee ,  NYMAND-GRARUP, Soeren ,  COHN, Marianne, Thorup ,  OLSEN, Peter, Bjarke ,  LI, Ming

IPC: C12N9/36 ,  A61K38/47

Abstract: Animal feed or animal feed additives comprising one or more polypeptides having lysozyme activity are disclosed. Polypeptides having lysozyme activity, polynucleotides encoding the polypeptides, nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides are also provided.

公开(公告)号：WO2003093453A3

公开(公告)日：2003-11-13

申请号：PCT/DK2003/000198

申请日：2003-03-25

Applicant: NOVOZYMES A/S ,  ANDERSEN, Jens, Tønne ,  JØRGENSEN, Steen, Troels ,  RASMUSSEN, Michael, Dolbjerg ,  OLSEN, Peter, Bjarke ,  CLAUSEN, Ib, Groth

Inventor： ANDERSEN, Jens, Tønne ,  JØRGENSEN, Steen, Troels ,  RASMUSSEN, Michael, Dolbjerg ,  OLSEN, Peter, Bjarke ,  CLAUSEN, Ib, Groth

IPC: C12N15/75

Abstract: A Bacillus licheniformis mutant host cell comprising a mutation ( deletion ) in one or more genes encoding contaminating native secreted polypeptides (e.g. proteolytic enzymes, nutrient uptake factors and signal molecules), wherein the mutant host cell expresses at least 5% less of the one or more proteases than the parent host cell, when cultivated under comparable conditions. The mutant host cell is used for producing heterologous polypeptides.

公开(公告)号：WO2003087149A2

公开(公告)日：2003-10-23

申请号：PCT/DK2003/000201

申请日：2003-03-25

Applicant: NOVOZYMES A/S ,  ANDERSEN, Jens, Tønne ,  JØRGENSEN, Steen, Troels ,  RASMUSSEN, Michael, Dolbjerg ,  OLSEN, Peter, Bjarke ,  CLAUSEN, Ib, Groth

Inventor： ANDERSEN, Jens, Tønne ,  JØRGENSEN, Steen, Troels ,  RASMUSSEN, Michael, Dolbjerg ,  OLSEN, Peter, Bjarke ,  CLAUSEN, Ib, Groth

IPC: C07K14/32

CPC classification number: C12N9/00 ,  C12N9/2408 ,  C12N9/2411 ,  C12N9/54 ,  C12P21/02 ,  C12R1/10 ,  C12Y302/01001

Abstract: A Bacillus licheniformis mutant host cell derived from a parent B. licheniformis host cell, which mutant host cell is mutated in one or more gene(s) encoding one or more polypeptide(s) having proteolytic activity which is at least 80% identical to one or more of the polypeptides shown in SEQ ID NO's: 2 to 84, wherein the mutant host cell expresses at least 5% less of the one or more polypeptide(s) having proteolytic activity than the parent host cell, when they are cultivated under comparable conditions

Abstract translation: 衍生自地衣芽孢杆菌宿主细胞的地衣芽孢杆菌突变宿主细胞，所述突变宿主细胞在编码一种或多种蛋白水解活性的多个基因中的一个或多个基因中突变，所述多肽与一种或多种多肽具有至少80％同一性 或更多个SEQ ID NO：2至84中所示的多肽，其中当它们在可比较的条件下培养时，突变宿主细胞表达具有比母体宿主细胞具有蛋白水解活性的一种或多种多肽的至少5％ 条件

公开(公告)号：WO2003087142A3

公开(公告)日：2003-10-23

申请号：PCT/DK2003/000199

申请日：2003-03-25

Applicant: NOVOZYMES A/S ,  ANDERSEN, Jens, Tønne ,  JØRGENSEN, Steen, Troels ,  RASMUSSEN, Michael, Dolbjerg ,  OLSEN, Peter, Bjarke ,  CLAUSEN, Ib, Groth

Inventor： ANDERSEN, Jens, Tønne ,  JØRGENSEN, Steen, Troels ,  RASMUSSEN, Michael, Dolbjerg ,  OLSEN, Peter, Bjarke ,  CLAUSEN, Ib, Groth

IPC: C12N15/75

Abstract: A Bacillus licheniformis mutant host cell comprising a mutation (deletion) in one or more genes encoding polypeptides involved in antibiotic synthesis, wherein the mutant host cell expresses at least 5% less of the one or more polypeptides involved in antibiotic synthesis than the parent host cell, when cultivated under comparable conditions. The mutant host cell is used for producing heterologous polypeptides.