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    ULTRA -CLEAN BAG OR BALLOON FOR COLLECTION OF VOLATILE ORGANIC COMPOUNDS IN BREATH OR AIR
    1.
    发明申请
    ULTRA -CLEAN BAG OR BALLOON FOR COLLECTION OF VOLATILE ORGANIC COMPOUNDS IN BREATH OR AIR 审中-公开
    用于收集呼吸或空气中挥发性有机化合物的ULTRA CLEAN袋或气球

    公开(公告)号：WO2017117545A1

    公开(公告)日：2017-07-06

    申请号：PCT/US2016/069539

    申请日：2016-12-30

    Applicant: PHILLIPS, Michael

    Inventor： PHILLIPS, Michael

    IPC: A61B5/08 ,  G01N30/04

    CPC classification number: A61B5/097 ,  A61B5/082 ,  G01N1/2202 ,  G01N33/497 ,  G01N2001/2244 ,  G01N2033/4975

    Abstract: A device and method is described for the collection of breath or air samples into a chemically clean bag or balloon, to facilitate analysis of volatile organic compounds (VOCs) in low concentrations in the collected samples. A reservoir of activated charcoal is introduced into the bag or balloon for initial removal of VOCs and it is then replaced with a similar reservoir of activated charcoal until the bag or balloon is employed to collect a sample. The device fulfills a long-felt need for collection of breath and air samples with a high VOC signal-to-noise ratio.

    Abstract translation: 描述了一种装置和方法，用于将呼吸或空气样品收集到化学清洁的袋子或气囊中，以便于分析收集的样品中低浓度的挥发性有机化合物（VOC）。 将活性炭储存器引入袋或气囊中以初始除去VOC，然后用类似的活性炭储存器替换，直到采用袋或气球收集样品。 该设备长期以来一直需要收集具有高VOC信噪比的呼吸和空气样本。

    A METHOD AND APPARATUS FOR IDENTIFICATION OF BIOMARKERS IN BREATH AND METHODS OF USING SAME FOR PREDICTION OF LUNG CANCER
    2.
    发明申请
    A METHOD AND APPARATUS FOR IDENTIFICATION OF BIOMARKERS IN BREATH AND METHODS OF USING SAME FOR PREDICTION OF LUNG CANCER 审中-公开
    识别呼吸生物标志物的方法和装置及其使用方法预测肺癌的方法和装置

    公开(公告)号：WO2018052689A1

    公开(公告)日：2018-03-22

    申请号：PCT/US2017/048668

    申请日：2017-08-25

    Applicant: PHILLIPS, Michael

    Inventor： PHILLIPS, Michael

    IPC: G01N33/497 ,  G01N30/02 ,  G01N30/72 ,  A61B5/08

    CPC classification number: G01N30/02 ,  A61B5/082 ,  A61B5/097 ,  G01N30/72 ,  G01N30/7206 ,  G01N30/8686

    Abstract: The present invention provides a method for identifying biomarkers and generating an output indicative of disease. The method for identifying biomarkers comprises the steps of collecting a breath sample from subjects known to have a disease and subjects known to be free of the disease; analyzing the collected breath samples to determine all mass ions in each of the collected breath samples using at least one time-resolved separation technique and at least one mass-resolved separation technique; identifying a subset of the determined mass ions in a processor as the biomarkers for detecting the disease, the subset of the determined mass ions are statistically significant for detecting the disease; and combining the subset of the determined mass ions in a multivariate algorithm in the processor to generate a value of a discriminant function indicating the likelihood that the subject has the disease.

    Abstract translation: 本发明提供了用于鉴定生物标志物并产生指示疾病的输出的方法。 用于鉴定生物标志物的方法包括以下步骤：从已知患有疾病的受试者和已知没有疾病的受试者收集呼吸样本; 分析所收集的呼吸样本以使用至少一种时间分辨分离技术和至少一种质量分辨分离技术来确定每个收集的呼气样本中的所有质量离子; 将处理器中确定的质量离子的子集识别为用于检测疾病的生物标志物，所确定的质量离子子集对于检测疾病具有统计显着性; 以及在处理器中将所确定的质量子离子的子集组合在多变量算法中以生成指示受试者患有疾病的可能性的判别函数的值。

    TISSUE MARKING SYSTEM
    3.
    发明申请
    TISSUE MARKING SYSTEM 审中-公开
    组织标记系统

    公开(公告)号：WO2006049962A1

    公开(公告)日：2006-05-11

    申请号：PCT/US2005/038399

    申请日：2005-10-25

    Applicant: PHILLIPS, Michael

    Inventor： PHILLIPS, Michael

    IPC: A61B19/00

    CPC classification number: A61B19/54 ,  A61B90/39 ,  A61B2090/3908 ,  A61B2090/395

    Abstract: A tissue marking system (120) that includes a first ink reservoir (125) that contains ink of a first color and a second ink reservoir (126) that contains ink of a second color different from the first color. A first isolation space (140) is positioned between the first ink reservoir and the second ink reservoir. A third ink reservoir (127) contains ink of a third color different from the first color and the second color. A second isolation space (145) is positioned between the second ink reservoir and the third ink reservoir.

    Abstract translation: 一种组织标记系统（120），其包括含有第一颜色的墨水的第一墨水储存器（125）和包含不同于第一颜色的第二颜色墨水的第二墨水储存器（126）。 第一隔离空间140位于第一储墨器和第二储墨器之间。 第三墨水储存器（127）包含不同于第一颜色和第二颜色的第三颜色的墨。 第二隔离空间（145）位于第二墨水储存器和第三墨水储存器之间。

    METHOD OF MANUFACTURE OF A MODIFIED MILK POWDER SUITABLE AS A RENNET CASEIN EXTENDER OR REPLACER
    4.
    发明申请
    METHOD OF MANUFACTURE OF A MODIFIED MILK POWDER SUITABLE AS A RENNET CASEIN EXTENDER OR REPLACER 审中-公开
    改性奶粉适用于RENNET CASEIN扩展器或更换器的方法

    公开(公告)号：WO2006066332A1

    公开(公告)日：2006-06-29

    申请号：PCT/AU2005/001935

    申请日：2005-12-20

    Applicant: MURRAY GOULBURN CO-OPERATIVE CO LIMITED ,  HARVEY, Janet ,  PHILLIPS, Michael ,  COOK, Warren

    Inventor： HARVEY, Janet ,  PHILLIPS, Michael ,  COOK, Warren

    IPC: A23J1/20 ,  A23C19/05 ,  A23C19/055

    CPC classification number: A23J3/34 ,  A23C19/054 ,  A23C19/055 ,  A23J1/20 ,  A23J1/202 ,  A23V2002/00 ,  A23V2300/34

    Abstract: A method for preparing a dairy protein concentrate, isolate or micellar casein, said method including the steps of: (a) preparing a pasteurised liquid skim milk, whole milk, milk protein concentrate or reconstituted milk feedstock; (b) subjecting the feedstock prepared above to membrane filtration to obtain a retentate having a protein content of between 50% and 95% by weight on a dry matter basis; (c) reacting said retentate with a proteolytic enzyme to modify the protein, for example to cleave the glycomacropeptide (GMP) from kappa-casein. The product of this method has sufficient functionality to enable it to be used as a replacer or extender for rennet casein in the manufacture of food products, particularly analog cheese products.

    Abstract translation: 一种制备乳蛋白浓缩物，分离物或胶束酪蛋白的方法，所述方法包括以下步骤：（a）制备巴氏消毒液体脱脂乳，全脂乳，乳蛋白浓缩物或复原奶原料; （b）使上述制备的原料进行膜过滤，以干物质为基础得到蛋白质含量为50％至95％的渗余物; （c）使所述滞留物与蛋白水解酶反应以改变蛋白质，例如从κ-酪蛋白切割糖巨肽（GMP）。 该方法的产品具有足够的功能，使其能够用作制造食品，特别是模拟干酪产品中的凝乳酶酪蛋白的替代物或延长剂。

    SURGICAL MARKER
    6.
    发明申请
    SURGICAL MARKER 审中-公开
    外科标志

    公开(公告)号：WO2006081491A2

    公开(公告)日：2006-08-03

    申请号：PCT/US2006/003077

    申请日：2006-01-27

    Applicant: VECTOR SURGICAL ,  PHILLIPS, Michael

    Inventor： PHILLIPS, Michael

    IPC: A61B17/00

    CPC classification number: A61B90/39 ,  A61B90/06 ,  A61B2090/061 ,  A61B2090/3908 ,  A61B2090/395 ,  A61B2090/3987

    Abstract: A surgical instrument for use with a trocar that provides access to an interior portion of a patient. The instrument includes an elongated rod portion sized to fit within the trocar and a leg portion attached to the elongated rod portion and movable with respect to the leg portion to define an acute angle therebetween. A marker is attached to the leg portion and is operable to apply a marking substance to the interior of the patient.

    Abstract translation: 一种与套管针一起使用的外科器械，其提供进入患者内部的通路。 仪器包括细长的杆部分，其尺寸适于装配在套针针内，并且腿部附接到细长杆部分并且可相对于腿部部分移动以在其间限定锐角。 标记物附接到腿部，并且可操作以将标记物质施加到患者的内部。

    IMPROVED BREATH COLLECTION APPARATUS
    9.
    发明申请
    IMPROVED BREATH COLLECTION APPARATUS 审中-公开

    公开(公告)号：WO2003049595A3

    公开(公告)日：2003-06-19

    申请号：PCT/US2002/038571

    申请日：2002-12-05

    Applicant: PHILLIPS, Michael

    Inventor： PHILLIPS, Michael

    IPC: A61B5/08

    Abstract: An arrangement for the collection, concentration, and optional analysis of volatile organic components in a alveolar breath includes a mouthpiece (20), a T-shaped valve unit (30), a breath reservoir (40), and a condensation unit (50) which removes water vapor from the alveolar breath.

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