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1.
公开(公告)号:WO2013158673A1
公开(公告)日:2013-10-24
申请号:PCT/US2013/036827
申请日:2013-04-16
CPC分类号: A61K39/0011 , A61K9/0019 , A61K9/1611 , A61K38/18 , A61K38/193 , A61K39/39 , A61K2039/55522 , A61K2039/55555 , A61K2039/55561 , A61K2300/00
摘要: A composition comprising mesoporous silica rods comprising an immune cell recruitment compound and an immune cell activation compound, and optionally comprising an antigen such as a tumor lysate. The composition is used to elicit an immune response to a vaccine antigen.
摘要翻译: 一种包含介孔二氧化硅棒的组合物,其包含免疫细胞募集化合物和免疫细胞活化化合物,并任选地包含抗原例如肿瘤裂解物。 该组合物用于引发对疫苗抗原的免疫应答。
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2.CELL-FRIENDLY INVERSE OPAL HYDROGELS FOR CELL ENCAPSULATION, DRUG AND PROTEIN DELIVERY, AND FUNCTIONAL NANOPARTICLE ENCAPSULATION 审中-公开
标题翻译: 细胞免疫反应用于细胞浸润,药物和蛋白质递送和功能纳米颗粒的水解公开(公告)号:WO2012148684A1
公开(公告)日:2012-11-01
申请号:PCT/US2012/033208
申请日:2012-04-12
申请人: PRESIDENT AND FELLOWS OF HARVARD COLLEGE , MOONEY, David, J. , KIM, Jaeyun , BENCHERIF, Sidi , LI, Weiwei, Aileen
CPC分类号: C12N5/0012 , A61L27/38 , A61L27/3834 , A61L27/52 , A61L27/54 , A61L27/56 , A61L2300/624 , A61L2400/08 , B82Y5/00 , C12N2533/74
摘要: The invention provides polymer scaffolds for cell-based tissue engineering.
摘要翻译: 本发明提供用于基于细胞的组织工程的聚合物支架。
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公开(公告)号:WO2016161372A1
公开(公告)日:2016-10-06
申请号:PCT/US2016/025717
申请日:2016-04-01
发明人: MOONEY, David, J. , SANDS, Roger, Warren , STERN, Joel, N., H. , LI, Weiwei, Aileen , DESAI, Rajiv , LU, Beverly, Ying
CPC分类号: A61K47/646 , A61K39/00 , A61K39/0008 , A61K39/0011 , A61K45/06 , A61K47/543 , A61K47/549 , A61K47/554 , A61K47/64 , A61K47/643 , A61K47/6957 , A61K2039/55522 , A61K2039/55561 , A61K2039/55566 , A61K2039/55572 , A61K2039/60 , A61K2039/6018 , A61K2039/6025 , A61L27/227 , A61L27/28 , A61L27/54 , A61L2300/416 , A61L2300/426 , A61L2300/43 , A61L2300/432 , A61L2300/45 , A61L2300/606 , A61L2430/02 , A61P1/00 , A61P3/08 , A61P11/06 , A61P17/00 , A61P17/06 , A61P17/10 , A61P19/02 , A61P25/00 , A61P29/00 , A61P31/00 , A61P35/00 , A61P37/00 , A61P37/06 , A61P37/08 , C07H21/00
摘要: The conjugate compositions and methods are useful to elicit/augment an immune response to a tumor or microbial infection or to reduce the severity of autoimmunity, chronic inflammation, allergy, asthma, periodontal disease, and transplant rejection.
摘要翻译: 缀合物组合物和方法可用于引发/增强对肿瘤或微生物感染的免疫应答或降低自身免疫,慢性炎症,过敏,哮喘,牙周病和移植排斥的严重性。
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公开(公告)号:WO2012167230A1
公开(公告)日:2012-12-06
申请号:PCT/US2012/040687
申请日:2012-06-04
申请人: PRESIDENT AND FELLOWS OF HARVARD COLLEGE , KIM, Jaeyun , MOONEY, David, J. , LI, Weiwei, Aileen , ARANY, Praveen , GADISH, Or
CPC分类号: A61K39/0011 , A61K38/193 , A61K41/0052 , A61K45/06 , A61K2039/5152 , A61K2039/5154 , A61K2039/54 , A61K2039/545 , A61K2039/55505 , A61K2039/55511 , A61K2039/55561 , A61K2039/57 , A61K2039/572 , A61K2039/70 , B82Y5/00
摘要: The invention provides compositions and methods for utilizing scaffolds in cancer vaccines.
摘要翻译: 本发明提供了在癌症疫苗中利用支架的组合物和方法。
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