中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

34 records (took 0.015 seconds)

    DETECTION OF BLADDER CANCER
    2.
    发明申请
    DETECTION OF BLADDER CANCER 审中-公开

    公开(公告)号：WO2020099895A1

    公开(公告)日：2020-05-22

    申请号：PCT/GB2019/053253

    申请日：2019-11-15

    Applicant: RANDOX LABORATORIES LTD

    Inventor： RUDDOCK, Mark ,  LAMONT, John ,  FITZGERALD, Stephen ,  WILLIAMSON, Kathleen

    IPC: G01N33/574

    Abstract: The present invention provides a method for detecting the presence or risk of bladder cancer in a female patient comprising the steps of detecting the presence of a panel of biomarkers in a sample isolated from a female patient, said panel of biomarkers comprising IL-13 and IL-12p70 and one or more biomarkers selected from BTA, Midkine, PAI-1/t PA, 8OHdG, CEA, CK18, Clusterin, Creatinine, CXCL16, Cystatin B, Cystatin C, d-Dimer, EGF, FAS, HAD, IL-1a, IL-1b, IL-4, IL-6, IL-7, IL-8, MCP-1, Microalbumin, MMP9NGAL, MMP9TIMP1, NGAL, NSE, Progranulin, TUP, TGFB1, Thrombomodulin, sTNFR1, TPA, VEGF and Triglycerides and/or the concentration of albumin/microalbumin/protein and creatinine expressed as an albumin:creatinine ratio in a sample i s o l a t e d f r o m a female patient; and assessing the results and comparing them to a normal control wherein an elevated presence of the biomarker compared to a normal control indicates the presence or risk of cancer in the patient from whom the sample is isolated.

    LIQUID SAMPLE COLLECTION DEVICE
    7.
    发明申请
    LIQUID SAMPLE COLLECTION DEVICE 审中-公开
    液体样品收集装置

    公开(公告)号：WO2015198019A1

    公开(公告)日：2015-12-30

    申请号：PCT/GB2015/051749

    申请日：2015-06-15

    Applicant: RANDOX LABORATORIES LTD

    Inventor： JACKSON, Stuart ,  MCCONNELL, Ivan ,  LAMONT, John ,  FITZGERALD, Stephen Peter

    IPC: A61B10/00

    CPC classification number: A61B10/007 ,  A61F5/441

    Abstract: A liquid sample collection device is provided. The liquid sample collection device comprises a housing including a liquid collection chamber, and a liquid supply conduit extending from an inlet port and in use generally downwardly to the collection chamber, wherein the collection chamber includes an air vent port located such that in use liquid supplied to the collection chamber through the liquid supply conduit displaces air through the air vent port, and wherein the liquid supply conduit follows a meandering path including at least one air trap section defined at the junction between portions of the conduit extending with upward and downward components respectively, whereby in use once the air vent port is closed, air is displaced along the liquid supply conduit until it is trapped by the air trap section thereby preventing further liquid flow through the conduit.

    Abstract translation: 提供液体样品收集装置。 所述液体样品收集装置包括壳体，所述壳体包括液体收集室和从入口端口大体向下延伸到所述收集室的液体供应管道，其中所述收集室包括通气口，所述通气口位于使用中的液体供应 通过液体供应管道将空气排出到通过排气口的空气，并且其中液体供应导管跟随蜿蜒路径，其包括至少一个限定在导管部分之间的连接部处的空气陷阱部分，分别与上部和下部部件分别延伸 一旦通气口关闭，空气就沿着液体供应管道移动，直到被空气捕获部分捕获，从而防止进一步的液体流过管道。

    RISK PREDICTION MODEL FOR PROSTATE CANCER
    9.
    发明申请
    RISK PREDICTION MODEL FOR PROSTATE CANCER 审中-公开

    公开(公告)号：WO2023017072A2

    公开(公告)日：2023-02-16

    申请号：PCT/EP2022/072425

    申请日：2022-08-10

    Applicant: RANDOX LABORATORIES LTD

    Inventor： FITZGERALD, Stephen Peter ,  RUDDOCK, Mark ,  LAMONT, John ,  MCKENNA, Declan

    IPC: G01N33/574

    Abstract: Single markers lack both sensitivity and specificity to stratify risk of PCa in patients who present with elevated tPSA and abnormal DRE. The novel combination of serum markers identified in this study could be employed to help triage patients into 'low' and 'high' risk categories, allowing general practitioners (GPs) to improve management of patients in primary care settings and potentially reducing the number of referrals for unnecessary, invasive, and costly treatments.

    IMMUNE CHECKPOINT INHIBITOR
    10.
    发明申请
    IMMUNE CHECKPOINT INHIBITOR 审中-公开

    公开(公告)号：WO2022096470A1

    公开(公告)日：2022-05-12

    申请号：PCT/EP2021/080423

    申请日：2021-11-02

    Applicant: RANDOX LABORATORIES LTD

    Inventor： DUNLOP, Marshall ,  SCHON, Shirley ,  LAMONT, John ,  FITZGERALD, Peter

    IPC: C07K16/28

    Abstract: The present invention relates to therapeutic antibodies, or antigen-binding portions thereof, for use in the treatment of cancer and infectious disease. Specifically, the present invention relates to therapeutic antibodies, or antigen-binding portions thereof, that target the programmed death-ligand 1 polypeptide. The present invention also relates to pharmaceutical compositions comprising said therapeutic antibody, or antigen-binding portions thereof.

Patent Agency Ranking