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    FLUIDIC CARD ASSEMBLY
    2.
    发明申请
    FLUIDIC CARD ASSEMBLY 审中-公开

    公开(公告)号：WO2019116009A1

    公开(公告)日：2019-06-20

    申请号：PCT/GB2018/053559

    申请日：2018-12-07

    Applicant: RANDOX LABORATORIES LTD

    Inventor： JACKSON, Stuart

    IPC: B01L3/00

    CPC classification number: B01L3/502 ,  B01L2200/0636 ,  B01L2200/0684 ,  B01L2300/0636 ,  B01L2300/0816 ,  B01L2300/0851 ,  B01L2400/0487

    Abstract: A fluidic card assembly (1) comprises an inlet (20) for introducing a fluid to the fluidic card assembly (1), a turbulent flow portion (30) downstream of the inlet (20), the turbulent flow portion (30) comprising a widening fluid channel (31) whereby a fluid introduced via the inlet (20) channel undergoes turbulence, and a laminar flow portion (40) downstream of the turbulent flow portion (30). The laminar flow portion (40) is configured to allow fluid passing from the turbulent flow portion (30) into the laminar flow portion (40) to establish a laminar flow pattern, and is configured to house a biochip (44) such that a fluid in the laminar flow portion (40) may be in contact with the biochip (44).

    MICROFLUIDIC CHIP
    4.
    发明申请
    MICROFLUIDIC CHIP 审中-公开
    微流控芯片

    公开(公告)号：WO2016059419A2

    公开(公告)日：2016-04-21

    申请号：PCT/GB2015/053068

    申请日：2015-10-15

    Applicant: RANDOX LABORATORIES LTD

    Inventor： JACKSON, Stuart ,  CROCKARD, Martin ,  HASWELL, Steve

    IPC: B01L3/00

    CPC classification number: B01L3/5027 ,  B01L3/5023 ,  B01L3/502738 ,  B01L2300/0887 ,  B01L2400/0644 ,  F16K99/0001 ,  F16K99/0013 ,  F16K2099/0084

    Abstract: According to the invention there is a microfluidic chip (1) that includes at least two layers (10) forming a stack of layers, each layer of which has at least one flow channel (14); a bore (16) extending through the layers and communicating with a plurality of flow channels; and a valve (20), which has a shaft (22) with a recess (222) in a side of the shaft for fluid to flow through. The shaft is rotatably mounted in the bore, and has a first position in which the recess is aligned with each of at least two flow channels of the plurality of flow channels thereby providing a flow path between said at least two flow channels, and a second position in which the recess is unaligned with at least one of said at least two flow channels the flow path between said at least two flow channels thereby being closed. This allows a fluid flow path between two flow channels to be open and closed by rotation of the shaft so that fluid in the microfluidic chip can be redirected to allow the chip to have greater capability and by using a minimal amount of space on the chip to do so.

    Abstract translation: 根据本发明，存在一个微流体芯片（1），其包括形成层叠层的至少两个层（10），每层具有至少一个流动通道（14）; 孔（16），其延伸穿过所述层并与多个流动通道连通; 以及阀（20），其具有在所述轴的侧面具有凹部（222）的轴（22），用于使流体流动。 轴可旋转地安装在孔中，并且具有第一位置，其中凹部与多个流动通道中的至少两个流动通道中的每一个对准，从而在所述至少两个流动通道之间提供流动路径，并且第二 所述凹部与所述至少两个流动通道中的至少一个不对齐的位置，所述至少两个流动通道之间的流动路径因此被封闭。 这允许两个流动通道之间的流体流动路径通过轴的旋转而打开和关闭，使得微流体芯片中的流体可以被重定向以允许芯片具有更大的能力，并且通过在芯片上使用最小量的空间 这样做。

    PIPETTE TIP DISPOSAL ASSEMBLY
    5.
    发明申请
    PIPETTE TIP DISPOSAL ASSEMBLY 审中-公开

    公开(公告)号：WO2020025972A1

    公开(公告)日：2020-02-06

    申请号：PCT/GB2019/052178

    申请日：2019-08-02

    Applicant: RANDOX LABORATORIES LTD

    Inventor： COURTNEY, Paul ,  REID, Martin ,  JACKSON, Stuart ,  LAMONT, John ,  MCCONNELL, Ivan ,  FITZGERALD, Peter

    IPC: B01L9/00 ,  B01L1/00

    Abstract: There is provided a pipette tip disposal assembly. The assembly comprises a receiving element adapted to support an end of at least one pipette tip, the at least one pipette tip being toppled in use from the receiving element along a first direction; and a container positioned to receive the at least one toppled pipette tip, the at least one pipette tip falling towards a base of the container on being received by the container. The base of the container has a first linear dimension aligned with the first direction corresponding to the length of a pipette tip.

    FLUIDIC CARD FOR ANALYSIS OF BIOCHIPS
    6.
    发明申请
    FLUIDIC CARD FOR ANALYSIS OF BIOCHIPS 审中-公开
    流体卡用于分析生物

    公开(公告)号：WO2017072513A1

    公开(公告)日：2017-05-04

    申请号：PCT/GB2016/053341

    申请日：2016-10-27

    Applicant: RANDOX LABORATORIES LTD

    Inventor： JACKSON, Stuart ,  CROCKARD, Martin ,  FITZGERALD, Stephen, Peter ,  LAMONT, John ,  MCCONNELL, Ivan

    IPC: C12Q1/68 ,  B01L3/00

    CPC classification number: C12Q1/6837 ,  B01L3/502707 ,  B01L3/502715 ,  B01L2200/028 ,  B01L2200/0689 ,  B01L2200/141 ,  B01L2300/0618 ,  B01L2300/0816 ,  B01L2300/087 ,  B01L2300/0883 ,  B01L2300/0887

    Abstract: A fluidic card assembly comprising a fluidic card housing (1) and a biochip (3) located in the fluidic card housing. The fluidic card housing (1) includes a chamber (2) with a base wall, into which at least one fluidic channel extends. The biochip (3) is at least partially located in the chamber. A seal (7) is provided for sealing the biochip in the chamber (2) when the biochip is urged into the chamber. The fluidic channel has a serpentine form. The seal may be laminated or laser welded to the opening of the chamber in order to provide a window for observing the biochip.

    Abstract translation: 流体卡组件包括流体卡外壳（1）和位于流体卡外壳中的生物芯片（3）。 流体卡外壳（1）包括具有基壁的腔室（2），至少一个流体通道延伸进入该腔室（2）。 生物芯片（3）至少部分地位于腔室中。 提供密封件（7）用于当生物芯片被推入腔室中时密封腔室（2）中的生物芯片。 流体通道具有蛇形形式。 密封件可以层压或激光焊接到室的开口，以提供观察生物芯片的窗口。

    METHOD OF EXTRACTING MATERIAL FROM A FLUID AND EXTRACTOR
    7.
    发明申请
    METHOD OF EXTRACTING MATERIAL FROM A FLUID AND EXTRACTOR 审中-公开
    从流体和提取器中提取物质的方法

    公开(公告)号：WO2018069724A1

    公开(公告)日：2018-04-19

    申请号：PCT/GB2017/053106

    申请日：2017-10-13

    Applicant: RANDOX LABORATORIES LTD

    Inventor： JACKSON, Stuart ,  FITZGERALD, Stephen Peter ,  MCCONNELL, Ivan ,  LAMONT, John

    IPC: B01D15/38 ,  B01F13/08 ,  C12N15/10

    Abstract: There is provided a method of extracting material from a fluid method of extracting material from a fluid, the fluid being held within a fluid chamber. Thee method comprises drawing, with a magnetic field generating system, at least one magnetically susceptible member through the fluid around a closed path between at least three points in the chamber, said at least one member being adapted to bind to material in fluid in the chamber. The at least three points are arranged relative to each other in a shape having at least two dimensions, the magnetic field generating system being configured to move the at least on magnetically susceptible member directly between the at least three points, material in the fluid binding to the at least one magnetically susceptible member when it comes into contact with the at least one member as it moves through the fluid.

    Abstract translation: 提供了一种从流体中提取材料的方法提取材料的方法，所述方法从流体中提取材料，所述流体被保持在流体腔室内。 该方法包括利用磁场生成系统通过流体在腔室中的至少三个点之间的闭合路径周围流动至少一个磁敏构件，所述至少一个构件适于结合腔室中的流体中的材料 。 所述至少三个点相对于彼此以具有至少两个维度的形状布置，所述磁场生成系统被配置为直接在所述至少三个点之间移动所述至少一个易受磁性的构件，所述流体中的材料结合到 所述至少一个磁敏构件在其穿过所述流体时与所述至少一个构件接触。

    CHEMILUMINESCENCE DETECTOR
    8.
    发明申请
    CHEMILUMINESCENCE DETECTOR 审中-公开
    化学发光检测器

    公开(公告)号：WO2017122027A1

    公开(公告)日：2017-07-20

    申请号：PCT/GB2017/050088

    申请日：2017-01-13

    Applicant: RANDOX LABORATORIES LTD

    Inventor： JACKSON, Stuart ,  MCCONNELL, Ivan ,  FITZGERALD, Peter

    IPC: G01N21/64 ,  G01N21/76

    CPC classification number: G01N21/76 ,  G01N21/6428 ,  G01N21/645 ,  G01N21/6452 ,  G01N21/6456 ,  G01N21/6486

    Abstract: The present invention provides a chemiluminescence detector (100), which comprises an image capture device (110) sensitive to chemiluminescence located within a container (120). The container has an array of apertures (130) located in a field of view of the image capture device, and each aperture is defined by a through-bore in a wall of the container. The exterior of the container is engagable with a plurality of sample holders (200), each sample holder being in alignment with a respective aperture when engaged with the exterior of the container. The passage of light into the container through each aperture is restrictable by a closure device (140), passage of light into the container through the apertures is thereby controllable.

    Abstract translation: 本发明提供化学发光检测器（100），其包括位于容器（120）内的对化学发光敏感的图像捕获装置（110）。 容器具有位于图像捕获装置的视场中的孔阵列（130），并且每个孔由容器的壁中的通孔限定。 容器的外部可与多个样品保持器（200）接合，每个样品保持器在与容器的外部接合时与相应的孔对齐。 光通过每个孔进入容器的通道可以通过闭合装置（140）来限制，从而通过孔进入容器的光可以被控制。

    LIQUID SAMPLE COLLECTION DEVICE
    9.
    发明申请
    LIQUID SAMPLE COLLECTION DEVICE 审中-公开
    液体样品收集装置

    公开(公告)号：WO2015198019A1

    公开(公告)日：2015-12-30

    申请号：PCT/GB2015/051749

    申请日：2015-06-15

    Applicant: RANDOX LABORATORIES LTD

    Inventor： JACKSON, Stuart ,  MCCONNELL, Ivan ,  LAMONT, John ,  FITZGERALD, Stephen Peter

    IPC: A61B10/00

    CPC classification number: A61B10/007 ,  A61F5/441

    Abstract: A liquid sample collection device is provided. The liquid sample collection device comprises a housing including a liquid collection chamber, and a liquid supply conduit extending from an inlet port and in use generally downwardly to the collection chamber, wherein the collection chamber includes an air vent port located such that in use liquid supplied to the collection chamber through the liquid supply conduit displaces air through the air vent port, and wherein the liquid supply conduit follows a meandering path including at least one air trap section defined at the junction between portions of the conduit extending with upward and downward components respectively, whereby in use once the air vent port is closed, air is displaced along the liquid supply conduit until it is trapped by the air trap section thereby preventing further liquid flow through the conduit.

    Abstract translation: 提供液体样品收集装置。 所述液体样品收集装置包括壳体，所述壳体包括液体收集室和从入口端口大体向下延伸到所述收集室的液体供应管道，其中所述收集室包括通气口，所述通气口位于使用中的液体供应 通过液体供应管道将空气排出到通过排气口的空气，并且其中液体供应导管跟随蜿蜒路径，其包括至少一个限定在导管部分之间的连接部处的空气陷阱部分，分别与上部和下部部件分别延伸 一旦通气口关闭，空气就沿着液体供应管道移动，直到被空气捕获部分捕获，从而防止进一步的液体流过管道。

    ASSAY FLUID DELIVERY SYSTEM
    10.
    发明申请
    ASSAY FLUID DELIVERY SYSTEM 审中-公开
    测定流体输送系统

    公开(公告)号：WO2015075447A1

    公开(公告)日：2015-05-28

    申请号：PCT/GB2014/053422

    申请日：2014-11-19

    Applicant: RANDOX LABORATORIES LTD

    Inventor： MATEAR, Jonathan ,  PANG, Robson ,  JACKSON, Stuart ,  SLOAN, David

    IPC: B01L3/00 ,  F04B9/04 ,  F04B19/00 ,  F04B1/04

    CPC classification number: B01L3/50273 ,  B01L3/502715 ,  B01L3/527 ,  B01L2200/027 ,  B01L2200/04 ,  B01L2200/0605 ,  B01L2200/0621 ,  B01L2200/10 ,  B01L2200/16 ,  B01L2300/0816 ,  B01L2300/123 ,  B01L2400/0478 ,  B01L2400/0481 ,  B01L2400/0487 ,  F04B9/042 ,  G01N35/00029 ,  G01N35/1002 ,  G01N2035/00148 ,  G01N2035/0486

    Abstract: There is provided an assay fluid delivery system comprising an array of fluid reservoirs (62), each of which is selectively actuatable to deliver a respective fluid to a fluid channel structure; and a fluid delivery control system (50) comprising a plurality of reciprocally mounted actuators, each associated with a respective reservoir and being movable between a retracted position and an actuating position at which it causes fluid to be delivered from the corresponding reservoir, a plurality of cams (22) with different profiles mounted on a common, rotatable cam shaft (6), each cam being engaged with a respective one of the actuators whereby rotation of the cams causes movement of the corresponding actuators between the retracted and actuating positions, and a motor coupled to the cam shaft for rotating the cam shaft, wherein the cams are shaped relative to one another so as to cause the corresponding actuators to actuate the reservoirs in a predetermined sequence and for predetermined respective times.

    Abstract translation: 提供了一种分析流体递送系统，其包括流体储存器阵列（62），每个流体储存器可选择性地致动以将相应的流体输送到流体通道结构; 以及流体输送控制系统（50），其包括多个往复安装的致动器，每个致动器与相应的储存器相关联并且可在缩回位置和致动位置之间移动，在该致动位置处，使得流体从相应的储存器输送， 具有不同轮廓的凸轮（22）安装在共同的可旋转的凸轮轴（6）上，每个凸轮与相应的一个致动器接合，由此凸轮的旋转引起相应致动器在缩回位置和致动位置之间的移动， 马达耦合到凸轮轴用于旋转凸轮轴，其中凸轮相对于彼此成形，以使相应的致动器以预定顺序并且预定的各个时间致动储存器。

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