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公开(公告)号：WO2022035846A1
公开(公告)日：2022-02-17
申请号：PCT/US2021/045374
申请日：2021-08-10
Applicant: SIEMENS HEALTHCARE DIAGNOSTICS INC.
Inventor： DESHPANDE, Manish , HOWARD III, Willis
IPC: F21L4/00 , F21V29/507 , F21V29/70
Abstract: A reagent analyzer having a circuit board, an imaging system and a processor is disclosed. The circuit board has a substrate, and a plurality of conductive leads. The substrate has a first and a second major surface. The first major surface is opposite the second major surface. The substrate has an opening extending between the first major surface and the second major surface. The reagent analyzer also includes an imaging system having a field of view extending through the opening formed in the substrate and configured to capture an image of a wet reagent test device positioned at a read position in the field of view, the image having a plurality of pixels. The processor is configured to receive the image, and to analyze pixels of the image to determine a presence or an absence of a target constituent being in a sample applied to the wet reagent pad.
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公开(公告)号：WO2015195636A1
公开(公告)日：2015-12-23
申请号：PCT/US2015/035988
申请日：2015-06-16
Applicant: SIEMENS HEALTHCARE DIAGNOSTICS INC.
Inventor： CHEN, Dafeng , RASMUSSEN, James E. , DESHPANDE, Manish
IPC: B01D19/00
CPC classification number: B01D19/0031 , B01D19/0063
Abstract: A fluidic device and a method for degassing a fluidic device are presented. The fluidic device includes a plurality of fluidic components such as channels, chambers, and integrated valves and pumps, etc. A porous membrane is disposed on a degassing area of the fluidic device for removing gas (such as, for example, bubbles) contained in a liquid. A fluid control device monitors a pressure profile indicating a pressure in the fluidic device over time and applies a pressure differential between two sides of the membrane when activated. The membrane is permeable to gas in the fluidic device and is impermeable to liquids through the pores under the pressure differential. The disclosed method enables degassing large volume of gas at a high flow rate and provides a bubble free filling in a fluidic device which is critical to precision sample metering, mixing, fluid control, reaction, and detection, etc.
Abstract translation: 提出了流体装置和用于对流体装置进行脱气的方法。 流体装置包括多个流体部件，例如通道，腔室，以及集成的阀和泵等。多孔膜设置在流体装置的脱气区域上，用于除去气体（例如气泡） 液体。 流体控制装置监测指示流体装置中随时间的压力的压力分布，并且当激活时在膜的两侧之间施加压力差。 该膜在流体装置中可渗透气体，并且在压力差下通过孔隙渗透液体。 所公开的方法使得能够以高流速对大体积的气体进行脱气，并且在流体装置中提供无气泡填充，这对精密样品计量，混合，流体控制，反应和检测等是至关重要的。
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公开(公告)号：WO2023064832A1
公开(公告)日：2023-04-20
申请号：PCT/US2022/078003
申请日：2022-10-13
Applicant: SIEMENS HEALTHCARE DIAGNOSTICS INC.
Inventor： DESHPANDE, Manish , ORTON, Emma
IPC: G06K7/12 , G01N21/84 , G01N33/487 , G01N33/53 , G06K7/10
Abstract: A reagent strip is described. The reagent strip includes a substrate and at least one reagent pad positioned on the substrate. The substrate has a storage unit storing control information, such as an authentication code, encoded as a part of a non-visible code. The authentication code may be used to determine if the reagent strip is authentic before testing is done or results are produced.
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公开(公告)号：WO2022226504A1
公开(公告)日：2022-10-27
申请号：PCT/US2022/071811
申请日：2022-04-20
Applicant: SIEMENS HEALTHCARE DIAGNOSTICS INC.
Inventor： DESHPANDE, Manish , WARNER, Ethan , ORTON, Emma
Abstract: An automated analyzer is described. The analyzer includes a housing, a consumable insert, a consumable support device, a reader and a control system. The housing has a sample port. The consumable insert has a consumable insert type and an identification component and receives a consumable. The consumable support device is disposed within the sample port, supports the consumable insert, and is moveable to a testing position within the internal cavity. The consumable support device has an identifier component configured to identify the consumable insert type based in part on the identification component and configured to output a first data signal indicative of the consumable insert type. The reader outputs a second data signal indicative of a reading from the consumable. The control system receives the first and second data signals, and interprets the second data signal based on the first data signal.
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公开(公告)号：WO2022066719A1
公开(公告)日：2022-03-31
申请号：PCT/US2021/051485
申请日：2021-09-22
Applicant: SIEMENS HEALTHCARE DIAGNOSTICS INC.
Inventor： KAUFFMANN, Aaron , DESHPANDE, Manish
IPC: G06K7/00
Abstract: A reagent strip is described. The reagent strip includes a substrate and at least one reagent pad positioned on the substrate. The substrate has a storage unit storing an authentication code. The authentication code has a lot value and a secondary value related to the lot value by a predetermined function assigned to the lot value.
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Patent Agency Ranking
公开(公告)号：WO2020118021A1
公开(公告)日：2020-06-11
申请号：PCT/US2019/064627
申请日：2019-12-05
Applicant: SIEMENS HEALTHCARE DIAGNOSTICS INC.
Inventor： SAMPRONI, Jennifer , DESHPANDE, Manish
Abstract: A device including a housing, a zone and a means for testing a fluid sample within the housing is disclosed. The housing is constructed of a fluid impermeable material, and defines a first fluid port, and a second fluid port. The first fluid port is configured to connect to a fluid collection device to receive a fluid sample from the fluid collection device into the housing. The second port is configured to pass the fluid sample from the housing into a testing instrument. The zone is formed in the housing. The zone is constructed of a material that allows an analysis of the fluid sample positioned within the housing, and located adjacent to the zone.
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公开(公告)号：WO2020118018A1
公开(公告)日：2020-06-11
申请号：PCT/US2019/064623
申请日：2019-12-05
Applicant: SIEMENS HEALTHCARE DIAGNOSTICS INC.
Inventor： SAMPRONI, Jennifer , DESHPANDE, Manish
Abstract: A blood testing device for detecting hemolysis in a blood sample is described. The blood testing device comprises an housing for containing the blood sample. The housing has a treatment window and an optical zone formed therein. The blood testing device further includes an acoustic transducer positioned to selectively generate acoustic forces directed into the treatment window of the housing and a control unit for selectively actuating and deactuating the acoustic transducer to permit colorimetric analysis of plasma within the blood sample.
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公开(公告)号：WO2019099842A1
公开(公告)日：2019-05-23
申请号：PCT/US2018/061540
申请日：2018-11-16
Applicant: SIEMENS HEALTHCARE DIAGNOSTICS INC.
Inventor： DESHPANDE, Manish , THORPE, William
IPC: G01N33/48
Abstract: A point of care system may comprise a plurality of diagnostic engines and an IDM in electronic communication with each of the plurality of diagnostic engines. Each of the plurality of diagnostic engines may perform testing on a sample inserted into the diagnostic engine. The IDM may be configured to communicate with each of the plurality of diagnostic engines to enable a plurality of tests to be performed on multiple different samples substantially simultaneously by a plurality of users using the plurality of diagnostic engines and to present a single user interface for managing testing by the plurality of diagnostic engines and for receiving the results of tests performed by each of the plurality of diagnostic engines.
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公开(公告)号：WO2014117067A1
公开(公告)日：2014-07-31
申请号：PCT/US2014/013152
申请日：2014-01-27
Applicant: SIEMENS HEALTHCARE DIAGNOSTICS INC.
Inventor： DESHPANDE, Manish , RASMUSSEN, James E. , CHEN, Dafeng
CPC classification number: B01L3/5027 , B01L3/545 , B01L2200/04 , B01L2200/14 , B01L2300/021 , B01L2300/0816 , B01L2400/0481 , B01L2400/0655
Abstract: Microfluidic chips may include one or more microfluidic elements and one or more channels providing fluid communication throughout the microfluidic chip. The microfluidic chips may also include an identifier for identifying a predetermined configuration of the one or more microfluidic elements and the one or more channels from a set of predetermined different configurations of the one or more microfluidic elements and the one or more channels.
Abstract translation: 微流控芯片可以包括一个或多个微流体元件和一个或多个通道，提供贯穿整个微流体芯片的流体连通。 微流体芯片还可以包括用于从一个或多个微流体元件和一个或多个通道的一组预定的不同配置中识别一个或多个微流体元件和一个或多个通道的预定配置的标识符。
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公开(公告)号：WO2022072230A1
公开(公告)日：2022-04-07
申请号：PCT/US2021/051916
申请日：2021-09-24
Applicant: SIEMENS HEALTHCARE DIAGNOSTICS INC.
Inventor： ISSANI, Siraj , PRADHAN, Simit , GALGALKAR, Sudipa , DESHPANDE, Manish
IPC: A61B5/00
Abstract: An image analysis system, a method and a point of care device are provided for determining, from an image of a cassette containing a sample, a concentration of one or more target analytes in the sample. The method includes identifying a region of interest (ROI) from the image corresponding to a result viewing area of the cassette, generating a unidimensional (1D) profile of the ROI, and probabilistically determining from the 1D profile, the concentration of the target analyte(s) in the sample based on a statistical model having one or more parameters of the 1D profile varying with respect to time and/or the concentration of the target analyte(s) in the sample.
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