中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

27 records (took 0.018 seconds)

    ADVANCED COATING APPARATUS AND METHOD
    1.
    发明申请
    ADVANCED COATING APPARATUS AND METHOD 审中-公开
    高级涂层装置和方法

    公开(公告)号：WO2004028699A2

    公开(公告)日：2004-04-08

    申请号：PCT/US2003/022632

    申请日：2003-07-17

    Applicant: SURMODICS, INC. ,  CHAPPA, Ralph, A. ,  CARLSON, Mark, F.

    Inventor： CHAPPA, Ralph, A. ,  CARLSON, Mark, F.

    IPC: B05B

    CPC classification number: B05B7/0807 ,  B05B7/0861 ,  B05B7/0869 ,  B05B13/0207 ,  B05B13/0228 ,  B05B13/0436 ,  B05B13/0442 ,  B05D1/002 ,  B05D1/02

    Abstract: A coating apparatus for coating a rollable device including a device rotator having a pair of rollers and spray nozzle is described. The spray nozzle produces a spray of coating material that is directed towards a gap that is between the rollers of the pair. The majority of any spray not deposited on the rollable device during a coating process passes through the gap between the rollers.

    Abstract translation: 描述了用于涂覆包括具有一对辊和喷嘴的装置转子的可卷装置的涂覆装置。 喷嘴产生涂层材料的喷雾，该涂层材料朝向该对辊子之间的间隙引导。 在涂布过程中没有沉积在可卷曲装置上的大部分喷雾都通过辊之间的间隙。

    ADDITIVES AND METHODS FOR ENHANCING ACTIVE AGENT ELUTION KINETICS
    2.
    发明申请
    ADDITIVES AND METHODS FOR ENHANCING ACTIVE AGENT ELUTION KINETICS 审中-公开
    添加剂和增强活性剂溶液动力学的方法

    公开(公告)号：WO2008088593A2

    公开(公告)日：2008-07-24

    申请号：PCT/US2007/079704

    申请日：2007-09-27

    Applicant: SURMODICS, INC. ,  CHAPPA, Ralph, A.

    Inventor： CHAPPA, Ralph, A.

    CPC classification number: A61K31/56 ,  A61K9/0024 ,  A61K9/0048 ,  A61K47/32 ,  A61L31/10 ,  A61L31/16 ,  A61L2300/222 ,  A61L2300/602 ,  C08L39/06 ,  C08L33/10 ,  C08L29/04

    Abstract: The present invention relates to methods and additives for increasing active agent elution rates from elution control coatings and elution control coatings including the same. In an embodiment the invention includes an elution control coating comprising a polymeric matrix and at least about 0.1 wt. % of an additive dispersed within the polymeric matrix. The additive can include polyvinylpyrrolidone or a copolymer thereof. An active agent can be dispersed within the polymeric matrix, the active agent having limited solubility in water. Embodiments of the invention also include a method of forming an elution control coating with accelerated release kinetics. Other embodiments are also included herein.

    Abstract translation: 本发明涉及用于增加洗脱控制涂层和包括其的洗脱控制涂层的活性剂洗脱速率的方法和添加剂。 在一个实施方案中，本发明包括洗脱控制涂层，其包含聚合物基质和至少约0.1wt。 ％的添加剂分散在聚合物基质内。 添加剂可以包括聚乙烯吡咯烷酮或其共聚物。 活性剂可以分散在聚合物基质内，活性剂在水中的溶解度有限。 本发明的实施方案还包括形成具有加速释放动力学的洗脱控制涂层的方法。 本文还包括其它实施例。

    METHOD FOR DEPOSITING A POLYMERIC COATING ON A SUBSTRATE
    3.
    发明申请
    METHOD FOR DEPOSITING A POLYMERIC COATING ON A SUBSTRATE 审中-公开
    在基材上沉积聚合物涂层的方法

    公开(公告)号：WO2006022854A1

    公开(公告)日：2006-03-02

    申请号：PCT/US2005/008802

    申请日：2005-03-16

    Applicant: SURMODICS, INC. ,  CHAPPA, Ralph, A.

    Inventor： CHAPPA, Ralph, A.

    IPC: B05D7/24

    CPC classification number: A61L29/085 ,  A61L27/34 ,  A61L31/10 ,  A61L2420/02 ,  B05D1/60 ,  B05D3/0218 ,  B05D2202/15 ,  C08L65/04

    Abstract: The present application relates to a method for vapor depositing a polymeric coating onto a substrate. In an embodiment, the invention is a method for applying a polymer coating to a substrate comprising performing a bake-out cycle with a chemical vapor deposition system and performing a deposition cycle with the chemical vapor deposition system.

    Abstract translation: 本申请涉及将聚合物涂层气相沉积到基底上的方法。 在一个实施方案中，本发明是一种将聚合物涂层施加到基底上的方法，包括用化学气相沉积系统进行烘烤循环并且与化学气相沉积系统一起进行沉积循环。

    RETENTION COATINGS FOR DELIVERY SYSTEMS
    6.
    发明申请
    RETENTION COATINGS FOR DELIVERY SYSTEMS 审中-公开
    用于输送系统的保持涂层

    公开(公告)号：WO2004020012A1

    公开(公告)日：2004-03-11

    申请号：PCT/US2003/026604

    申请日：2003-08-25

    Applicant: SURMODICS, INC. ,  STUCKE, Sean, M. ,  LINDSOE, Kimberly, K., M. ,  CHAPPA, Ralph, A. ,  SWAN, Dale, G.

    Inventor： STUCKE, Sean, M. ,  LINDSOE, Kimberly, K., M. ,  CHAPPA, Ralph, A. ,  SWAN, Dale, G.

    IPC: A61L27/34

    CPC classification number: A61L31/16 ,  A61L29/085 ,  A61L29/16 ,  A61L31/10 ,  A61L2300/258 ,  A61L2300/404 ,  A61L2300/406 ,  A61L2300/606 ,  C08L71/02

    Abstract: A coating composition, in both its uncrosslinked and crosslinked forms, for use in increasing the static friction of a surface of a delivery system comprising a medical device having a surface in contact with the surface of a delivery component, the static friction of the surface being increased in an amount sufficient to substantially maintain the position of the medical device on the delivery component against forces asserted on the delivery system as it navigates through a vessel of the body. The delivery system may comprise a balloon catheter as the delivery component and a stent as the medical device. A composition includes a polyether monomer, such as an alkoxy poly(alkylene glycol), a carboxylic acid-containing monomer, such as (meth)acrylic acid, optionally a photoderivatized monomer, and a hydrophilic monomer such as (meth)acrylamide.

    Abstract translation: 一种涂料组合物，以其未交联和交联的形式，用于增加递送系统的表面的静摩擦力，其包括具有与输送组分表面接触的表面的医疗装置，表面的静摩擦力 增加的量足以基本上保持医疗装置在输送部件上的位置，抵抗在输送系统导航通过身体的血管时所断言的力。 输送系统可以包括作为输送部件的气囊导管和作为医疗装置的支架。 组合物包括聚醚单体，例如烷氧基聚（亚烷基二醇），含羧酸的单体，例如（甲基）丙烯酸，任选的光衍生单体和亲水性单体如（甲基）丙烯酰胺。

    DOUBLE WALL CATHETER FOR DELIVERING THERAPEUTIC AGENT
    7.
    发明申请
    DOUBLE WALL CATHETER FOR DELIVERING THERAPEUTIC AGENT 审中-公开
    用于输送治疗剂的双壁导管

    公开(公告)号：WO2012096787A1

    公开(公告)日：2012-07-19

    申请号：PCT/US2011/067722

    申请日：2011-12-29

    Applicant: SURMODICS, INC. ,  CHAPPA, Ralph, A.

    Inventor： CHAPPA, Ralph, A.

    IPC: A61M25/10 ,  A61L29/08

    CPC classification number: A61M25/1011 ,  A61L29/085 ,  A61L29/16 ,  A61L2300/00 ,  A61M2025/1013 ,  A61M2025/105 ,  A61M2025/1075 ,  A61M2025/1086

    Abstract: The present invention relates to a catheter assembly (10) that can deliver a therapeutic composition. The catheter assembly can include an outer balloon (30) with openings (36) for releasing the therapeutic composition. When the catheter assembly is in its contracted state, the openings are closed, and the assembly retains the therapeutic composition. When the catheter assembly is in its dilated state, the openings are open, and the therapeutic composition is released. The present invention also includes methods of making and using such a catheter assembly.

    Abstract translation: 本发明涉及可递送治疗组合物的导管组件（10）。 导管组件可包括具有释放治疗组合物的开口（36）的外球囊（30）。 当导管组件处于收缩状态时，开口关闭，并且组件保持治疗组合物。 当导管组件处于其扩张状态时，开口是开放的，并且治疗组合物被释放。 本发明还包括制造和使用这种导管组件的方法。

    COATINGS AND METHODS FOR CONTROLLED ELUTION OF HYDROPHILIC ACTIVE AGENTS
    8.
    发明申请
    COATINGS AND METHODS FOR CONTROLLED ELUTION OF HYDROPHILIC ACTIVE AGENTS 审中-公开
    亲水性活性剂受控排放的涂层和方法

    公开(公告)号：WO2012058274A2

    公开(公告)日：2012-05-03

    申请号：PCT/US2011/057826

    申请日：2011-10-26

    Applicant: CHAPPA, Ralph, A. ,  BURKSTRAND, Michael, J. ,  BABCOCK, David, E. ,  SURMODICS, INC.

    Inventor： CHAPPA, Ralph, A. ,  BURKSTRAND, Michael, J. ,  BABCOCK, David, E.

    IPC: A61L27/34 ,  A61L31/10

    CPC classification number: A61L31/10 ,  A61L27/34 ,  A61L27/54 ,  A61L31/16 ,  A61L2420/02 ,  C08L31/04

    Abstract: Embodiments of the invention include multi-layer coatings and methods for controlling the elution of hydrophilic active agents. In an embodiment, the invention includes a medical device including a substrate, a primer polymer layer disposed on the substrate, an expandable layer disposed on the primer polymer layer, and a hydrophilic active agent dispersed within the expandable layer. In an embodiment, the invention includes a method of forming a medical device including depositing a primer layer onto a substrate, the primer layer comprising a primer polymer. The method can further include depositing an expandable layer onto the primer layer, the expandable layer including an expandable polymer, and a hydrophilic active agent. The expandable layer can be deposited with a solvent that is effective to solvate both the expandable polymer and the primer polymer. Other embodiments are also included herein.

    Abstract translation: 本发明的实施方案包括用于控制亲水性活性剂洗脱的多层涂层和方法。 在一个实施方案中，本发明包括医疗装置，其包括基底，设置在基底上的底漆聚合物层，设置在底漆聚合物层上的可膨胀层以及分散在可膨胀层内的亲水性活性剂。 在一个实施方案中，本发明包括一种形成医疗装置的方法，该方法包括将底漆层沉积到基底上，该底漆层包含底漆聚合物。 该方法可以进一步包括将可膨胀层沉积到底层上，可膨胀层包括可膨胀聚合物和亲水活性剂。 可膨胀层可以用有效溶解可膨胀聚合物和底层聚合物的溶剂沉积。 其他实施例也包括在本文中。

    COATING APPLICATION SYSTEM WITH SHAPED MANDREL
    9.
    发明申请
    COATING APPLICATION SYSTEM WITH SHAPED MANDREL 审中-公开
    涂层应用系统与形状的MANDREL

    公开(公告)号：WO2009132214A1

    公开(公告)日：2009-10-29

    申请号：PCT/US2009/041575

    申请日：2009-04-23

    Applicant: SURMODICS, INC. ,  CHAPPA, Ralph, A. ,  ARPS, James

    Inventor： CHAPPA, Ralph, A. ,  ARPS, James

    IPC: B05B13/02

    CPC classification number: A61F2/82 ,  A61F2240/001 ,  B05B13/0242 ,  B05B13/0442

    Abstract: The invention relates to systems and methods for applying coatings to devices. In an embodiment, the invention includes a coating apparatus including a mandrel having a lengthwise axis and an exterior surface, the exterior surface of the mandrel defining a plurality of channels disposed parallel to the lengthwise axis, the mandrel configured to rotate around the lengthwise axis; and a spray head configured to direct a stream of material at the mandrel. In an embodiment the invention includes a method of applying a coating to a medical device. Other embodiments are also included herein.

    Abstract translation: 本发明涉及将涂料涂覆到装置上的系统和方法。 在一个实施例中，本发明包括涂覆设备，其包括具有纵向轴线和外表面的心轴，心轴的外表面限定平行于纵向轴线设置的多个通道，心轴构造成围绕纵向轴线旋转; 以及喷头，其配置成在心轴处引导材料流。 在一个实施方案中，本发明包括将涂层施加到医疗装置的方法。 本文还包括其它实施例。

Patent Agency Ranking