公开(公告)号：WO2016141195A1

公开(公告)日：2016-09-09

申请号：PCT/US2016/020711

申请日：2016-03-03

Applicant: TRANSMED7, LLC

Inventor： VETTER, James, W. ,  VETTER, Eugene, H. ,  VETTER, Alisen, E.

IPC: A61M25/10

CPC classification number: A61M25/1011 ,  A61B17/32 ,  A61M25/0054 ,  A61M25/0155 ,  A61M25/1002 ,  A61M2025/0057 ,  A61M2025/105 ,  A61M2025/1072 ,  A61M2205/02 ,  A61N5/1002

Abstract: A steerable, conformable, drug eluting balloon catheter device may comprise a catheter stem with one or more balloon element(s), themselves comprised of one or more segment(s) arranged radially or axially along the length of the device, and may allow precise deployment of vascular interventional devices, including coring devices and/or placement of stents, and may also allow targeted, specific placement of selected diagnostic or therapeutic materials on the walls of a vascular structure during a cardiovascular intervention procedure.

Abstract translation: 可导向，顺应的药物洗脱球囊导管装置可以包括具有一个或多个球囊元件的导管杆，其本身由沿着装置的长度径向或轴向布置的一个或多个节段组成，并且可以允许精确 包括取心装置和/或放置支架的血管介入装置的部署，并且还可以允许在心血管介入手术期间将选定的诊断或治疗材料定位在血管结构的壁上。

公开(公告)号：WO2016044693A1

公开(公告)日：2016-03-24

申请号：PCT/US2015/050868

申请日：2015-09-18

Applicant: TRANSMED7, LLC

Inventor： VETTER, James, W. ,  VETTER, Eugene, H.

IPC: A61B10/02 ,  A61B17/00 ,  A61B17/28

CPC classification number: A61B10/0266 ,  A61B10/0283 ,  A61B10/06 ,  A61B2010/0208 ,  A61B2017/00309

Abstract: A device for soft tissue biopsy or excision for either handheld or stereotactic table use may comprise a work element configured to selectively open and close at least one articulable beak configured to penetrate tissue, or follow a central lumen of another device or over a wire in a longitudinal direction. Flush and vacuum tissue transport mechanisms may be incorporated. A single tube or an inner sheath and an outer sheath which may be co-axially disposed relative to a work element may be configured to actuate a beak or beaks and provisions for simultaneous beak closing under rotation may be incorporated.

Abstract translation: 用于软组织活检或切除手术或立体定向台用的装置可以包括工作元件，其被配置为选择性地打开和关闭构造成穿透组织的至少一个可铰接的喙，或者沿着另一装置的中心内腔或沿着线 纵向。 可并入冲洗和真空组织输送机构。 可以相对于工作元件同轴设置的单管或内护套和外护套可以被配置为致动喙或喙，并且可以并入用于在旋转下同时关闭的准备。

公开(公告)号：WO2014105271A1

公开(公告)日：2014-07-03

申请号：PCT/US2013/068989

申请日：2013-11-07

Applicant: TRANSMED7, LLC

Inventor： VETTER, Eugene, H. ,  VETTER, James, W. ,  VETTER, Alisen, E.

IPC: A61B17/3205

CPC classification number: A61B10/0266 ,  A61B10/025 ,  A61B10/0283 ,  A61B17/320016 ,  A61B17/3205 ,  A61B17/32056 ,  A61B18/149 ,  A61B2010/0208

Abstract: An excisional biopsy and delivery device may comprise one or more rotating, penetrating and cutting rod elements. The rod elements may be configured to advance from a stored and confined first position and rotate about an axis, while being simultaneously revolved about a central axis. The rod elements may then assume a second released and expanded configuration that is operative to cut around and surround target tissue. In this manner, the rod elements are operative to move through the surrounding tissue to create a volume of revolution and to sever and capture the target tissue contained within fee volume of revolution from fee surrounding tissue. The severed and captured volume of revolution, containing fee target issue may then be removed.

Abstract translation: 切除活检和递送装置可以包括一个或多个旋转，穿透和切割杆元件。 杆元件可以被配置为从存储和限制的第一位置前进并围绕轴线旋转，同时围绕中心轴线旋转。 杆元件然后可以呈现第二释放和扩张构型，其可操作以围绕和围绕目标组织。 以这种方式，杆元件可操作以移动通过周围组织以产生一定量的旋转，并且从费用周围的组织切断并捕获包含在费用体积内的目标组织。 可以删除包含费用目标问题的被切断和革命的革命。

公开(公告)号：WO2016138424A1

公开(公告)日：2016-09-01

申请号：PCT/US2016/019851

申请日：2016-02-26

Applicant: TRANSMED7, LLC

Inventor： VETTER, James, W. ,  VETTER, Eugene, H.

IPC: A61B17/3207

CPC classification number: A61B17/320725 ,  A61B17/320758 ,  A61B2017/22055 ,  A61B2017/22061 ,  A61B2017/22067 ,  A61B2017/22071 ,  A61B2090/0801

Abstract: A vascular interventional device may comprise a combination of inflatable and cutting elements and embodiments may comprise structures and functionality for dilatation of blood vessels narrowed by diseases, removal of plaque and debris from diseased blood vessels and delivery of drugs for the prevention of re-narrowing of vessel luminal cross-section area as well as to provide scaffolding when needed to keep vessels patent.

Abstract translation: 血管介入装置可以包括可膨胀和切割元件的组合，并且实施方案可以包括用于扩张由疾病缩小的血管的结构和功能，从患病血管中除去斑块和碎屑以及递送药物以防止再狭窄 容器管腔横截面积，以及在需要时提供脚手架以保持船舶专利。

公开(公告)号：WO2016061373A1

公开(公告)日：2016-04-21

申请号：PCT/US2015/055772

申请日：2015-10-15

Applicant: TRANSMED7, LLC

Inventor： VETTER, James, W. ,  VETTER, Eugene, H.

IPC: A61M29/00

CPC classification number: A61B17/320725 ,  A61B17/221 ,  A61B17/320758 ,  A61B2017/22079 ,  A61B2017/2212 ,  A61B2017/320716 ,  A61B2017/320733 ,  A61F2/013 ,  A61F2002/018

Abstract: A device for intra-vascular embolic-thrombolic protection, as well as embolectomy/thrombectomy and atherectomy interventional procedures and methods. At least a portion of the working end of the device may be formed monolithically from a single hypodermic tube, or may be formed of monolithic inner and outer tubes with fixed or movable guide wire elements and imaging modalities. The device may comprise structures enabling coring, expansion within a vascular stnicture and vascular wall shaving, as well as filtration, stabilization and capturing of thrombotic or embolitic material during an intervention procedure.

Abstract translation: 用于血管内栓塞 - 栓塞保护的装置，以及止血切除术/血栓切除术和粥样斑块切除术介入手术和方法。 装置的工作端的至少一部分可以由单个皮下注射管整体地形成，或者可以由具有固定或可移动的导丝元件和成像模式的整体内管和外管形成。 该装置可以包括在介入手术过程中能够使血管栓塞和血管壁剃毛中的取芯，扩张以及血栓形成或栓塞材料的过滤，稳定和捕获的结构。

公开(公告)号：WO2016044226A2

公开(公告)日：2016-03-24

申请号：PCT/US2015/050118

申请日：2015-09-15

Applicant: TRANSMED7, LLC

Inventor： VETTER, James, W. ,  VETTER, Eugene, H.

IPC: A61B17/12

CPC classification number: A61M37/00 ,  A61B10/06 ,  A61B17/3468 ,  A61B17/3478 ,  A61B2090/3987 ,  A61M5/00 ,  A61M37/0069 ,  A61N5/1007 ,  A61N2005/1008

Abstract: An in-situ material delivery device for handheld, stereotactic table or MRI stage use may comprise a work element configured to selectively open and close at least one articulable beak configured to penetrate tissue to a target delivery site, or follow a central lumen of another device or other guiding modality, and then to deliver selected materials. Such a device may deliver a variety of materials such as markers, radio-active pellets, medications, other devices, and other materials of solid, liquid or gaseous form to a target site, and materials of similar nature may also be captured and removed from a target site. A single tube with or without coatings or an inner sheath and an outer sheath which may be co-axially disposed relative to a work element may be configured to actuate a beak or beaks and internal delivery mechanisms simultaneously. One embodiment of this device may be applicable to field use or one time use.

Abstract translation: 用于手持式，立体定向台或MRI级使用的原位输送装置可包括工作元件，其被配置为选择性地打开和关闭构造成穿透组织至目标递送部位的至少一个可铰接喙，或者跟随另一装置的中心腔 或其他指导模式，然后提供所选材料。 这样的装置可以将诸如标记物，放射性活性丸剂，药物，其它装置以及固体，液体或气体形式的其它材料的各种材料递送到目标部位，并且也可以捕获和除去具有相似性质的材料 目标网站。 具有或不具有涂层或可以相对于工件的同轴设置的内护套和外护套的单管可以构造成同时致动喙或喙和内部输送机构。 该装置的一个实施例可以适用于现场使用或一次使用。

公开(公告)号：WO2016144834A1

公开(公告)日：2016-09-15

申请号：PCT/US2016/021088

申请日：2016-03-05

Applicant: TRANSMED7, LLC

Inventor： VETTER, Eugene, H. ,  VETTER, James, W.

IPC: A61B10/00 ,  A61B10/02 ,  A61B10/04

CPC classification number: A61B17/32002 ,  A61B10/0233 ,  A61B10/025 ,  A61B10/0266 ,  A61B10/0283 ,  A61B17/1637 ,  A61B17/320758 ,  A61B2010/0225 ,  A61B2017/320024 ,  A61B2017/320032 ,  A61B2017/320775

Abstract: A soft tissue biopsy or material collection device may comprise a work element consisting of an outer tube with external sheath and formed from a tapered helical structure over an internal tube structure configured to open and close its distal end to perform penetration, coring, capturing, parting off and transporting multiple material samples in a single or multiple insertion procedure.

Abstract translation: 软组织活组织检查或材料收集装置可以包括由具有外护套的外管组成的工件，该外管由内管结构上的锥形螺旋结构形成，该内管结构构造成打开和关闭其远端以进行穿透，取芯，捕获，分离 在单个或多个插入程序中关闭并运输多个材料样品。

公开(公告)号：WO2016141186A1

公开(公告)日：2016-09-09

申请号：PCT/US2016/020688

申请日：2016-03-03

Applicant: TRANSMED7, LLC

Inventor： VETTER, James, W. ,  VETTER, Eugene, H.

IPC: A61B10/02 ,  A61B10/04 ,  A61B10/06 ,  A61B17/28

CPC classification number: A61B10/0283 ,  A61B10/0096 ,  A61B10/0266 ,  A61B17/28 ,  A61B17/32053 ,  A61B2010/0208 ,  A61B2017/00862 ,  A61B2017/320064 ,  A61B2217/005 ,  A61M1/007 ,  A61M25/0662

Abstract: A device comprises a syringe comprising a syringe body portion and a plunger portion configured to engage with and slide axially within the body portion; a tube set fitted to the syringe. The tube set may comprise a proximal tube attached to the plunger portion at a proximal end thereof and terminated, at a distal end thereof, by a beak assembly configured to assume a first configuration suitable for coring through tissue and a second configuration suitable for tissue penetration and parting off tissue; and a distal tube disposed over and coupled to the proximal tube to enable travel-limited axial displacement relative to the proximal tube. Axially moving the plunger portion of the plunger portion within the body portion of the syringe causes differential movement of the proximal tube relative to the distal tube to selectively cause the beak assembly to assume the first or the second configuration.

Abstract translation: 一种装置包括注射器，其包括注射器主体部分和构造成在主体部分内与轴向接合并滑动的柱塞部分; 安装在注射器上的管套。 管组可以包括在其近端处附接到柱塞部分的近端管，并且在其远端处由构造成呈现适于通过组织取芯的第一构造的喙组件和适于组织穿透的第二构造而终止 并脱离组织; 以及设置在近侧管上并耦合到近侧管的远端管，以使得能够相对于近端管的行进限制的轴向位移。 将柱塞部分的柱塞部分轴向移动在注射器的主体部分内导致近端管相对于远端管的差动运动，以选择性地使喙组件呈现第一或第二构型。

公开(公告)号：WO2015026979A3

公开(公告)日：2015-02-26

申请号：PCT/US2014/051945

申请日：2014-08-20

Applicant: TRANSMED7, LLC

Inventor： VETTER, James, W. ,  VETTER, Eugene, H. ,  CLARK, Daniel, E. ,  VETTER, Alisen, E.

IPC: A61B10/02

Abstract: An excisional device for either handheld or stereotactic table use may comprise an outer sheath that may comprise a distal scoopula shape configured to penetrate and/or cut tissue independently or in concert with, work element(s). The articulable work element(s) may comprise articulable beak(s) and may be configured to translate and/or rotate at a first rate and to cut tissue in a direction implied by placement, of the scoopula shaped outer sheath. A first helical element or equivalent assembly may be configured to transport tissue cut by the work element(s) and/or scoopula, may be co-axially disposed relative to the work element(s) and may be operative to rotate at a second rotation rate that is different than the first rate. A proximal sheath may be co-axially disposed relative to the work element(s) and the first helical element, and may be configured to rotate and actuate the work element(s).

公开(公告)号：WO2016053742A1

公开(公告)日：2016-04-07

申请号：PCT/US2015/051906

申请日：2015-09-24

Applicant: TRANSMED7, LLC

Inventor： VETTER, James, W. ,  VETTER, Eugene, H.

IPC: A61B10/00

CPC classification number: A61B17/3207 ,  A61B10/0266 ,  A61B10/06 ,  A61B17/320068 ,  A61B17/3201 ,  A61B17/3205 ,  A61B17/32053 ,  A61B2010/0208 ,  A61B2017/00685 ,  A61B2017/2903 ,  A61B2017/320064 ,  A61B2217/005

Abstract: A platform device for material excision or removal from vascular structures for either handheld or stereotactic table use may comprise a work, element or elements configured to selectively open and close at least one articulable beak or scoopula configured to penetrate and remove intra-vascular materials or obstructions, or follow a central lumen o.f another device or over a wire in a longitudinal direction. Flush and vacuum tissue transport mechanisms may be incorporated. A single tube or an inner sheath and an outer sheath which may be co-axially disposed relative to a work element may be configured to actuate a beak or beaks or scoopulas and provisions for simultaneous beak or scoopula closing under rotation may be incorporated.

Abstract translation: 用于手术或立体定向台使用的血管结构材料切除或去除的平台装置可以包括构造成选择性地打开和关闭至少一个可铰接的喙或勺子的构件，用于穿透和移除血管内材料或障碍物 ，或沿着另一装置的中央腔或沿着纵向方向上的电线。 可并入冲洗和真空组织输送机构。 可以将可相对于工作元件同轴设置的单个管或内护套和外护套构造成致动喙或喙或勺，并且可以并入用于在旋转下同时进行喙或勺关闭的设置。