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    SHEATHS, METHODS OF USE, AND KITS INCLUDING THE SAME
    1.
    发明申请
    SHEATHS, METHODS OF USE, AND KITS INCLUDING THE SAME 审中-公开
    SHEATHS，使用方法以及包括它们的套件

    公开(公告)号：WO2017180419A1

    公开(公告)日：2017-10-19

    申请号：PCT/US2017/026283

    申请日：2017-04-06

    Applicant: BAYLOR COLLEGE OF MEDICINE

    Inventor： YADAV, Naveen ,  RAI, Arun ,  GRAZIANO, Christopher ,  SONI, Samit ,  LINK, Richard

    IPC: A61B17/02 ,  A61B17/34

    CPC classification number: A61M25/0662 ,  A61B17/22 ,  A61B2017/22038 ,  A61B2017/22067 ,  A61M25/09 ,  A61M25/10 ,  A61M25/10186 ,  A61M2210/1082

    Abstract: One aspect of the invention provides a sheath including: a cylinder defining a central passage; a balloon located along an external surface of a distal end of the cylinder, the balloon lying substantially flush with or recessed from the external surface when deflated, but capable of projecting beyond the external surface when inflated; and an inflation port located at a proximal end of the cylinder, the inflation port in fluid communication with the balloon. Another aspect of the invention provides a kit including: a sheath as described herein and instructions for use.

    Abstract translation: 本发明的一个方面提供了一种护套，其包括：限定中心通道的圆柱体; 气囊，所述气囊沿着所述圆筒的远端的外表面定位，所述气囊在放气时与所述外表面基本平齐或从所述外表面凹入，但能够在膨胀时突出超过所述外表面; 以及位于圆筒近端处的膨胀端口，膨胀端口与气囊流体连通。 本发明的另一方面提供了一种套件，其包括：如本文所述的护套和使用说明。

    DEVICES AND METHODS FOR REMOVAL OF ACUTE BLOCKAGES FROM BLOOD VESSELS
    3.
    发明申请
    DEVICES AND METHODS FOR REMOVAL OF ACUTE BLOCKAGES FROM BLOOD VESSELS 审中-公开
    用于从血管中去除急性阻塞的装置和方法

    公开(公告)号：WO2017097616A1

    公开(公告)日：2017-06-15

    申请号：PCT/EP2016/078973

    申请日：2016-11-28

    Applicant: NEURAVI LIMITED

    Inventor： VALE, David ,  CASEY, Brendan ,  GILVARRY, Michael ,  MCARDLE, Kevin ,  HOLIAN, Maeve ,  HARDIMAN, David ,  KEANE, Alan ,  KING, Daniel ,  O'GORMAN, Jacqueline ,  BRADY, Eamon

    IPC: A61B17/22 ,  A61M1/00

    CPC classification number: A61B17/22031 ,  A61B17/22 ,  A61B17/29 ,  A61B17/3421 ,  A61B2017/22034 ,  A61B2017/22067 ,  A61B2017/22079 ,  A61B2017/2212 ,  A61B2017/2215 ,  A61B2217/005 ,  A61M1/008

    Abstract: A catheter has an expansile tip 901 that can be delivered in a constricted form. The increased tip diameter facilitates the aspiration and removal of large clot volumes by increasing the area of the catheter tip that applies aspiration to the clot. The tip 901 comprises a support frame which can be cut from a metal or polymer tube, covered with a thin polymer sleeve 909 containing highly elastic properties. This construction provides good pushability and high compressive resistance. The cut pattern can contain axial connections of the support frame 908 and ring members 906, which will provide a large level of axial support, lateral flexibility and hoop strength to withstand aspiration. The tip of the device can contain a section 907 proximal of the highly flexible area 905 that can expand to except clot. This potential to increase body diameter facilitates the retrieval of large volume clots while the construction of the catheter provides good column stiffness to avoid axial collapse and still maintain good flexibility.

    Abstract translation: 导管具有可以收缩形式递送的可膨胀尖端901。 增加的尖端直径通过增加导管尖端的适用于凝块的抽吸区域来促进大量凝块体积的抽吸和去除。 尖端901包括支撑框架，该支撑框架可以由金属或聚合物管切割，覆盖有包含高度弹性特性的薄聚合物套筒909。 这种结构提供了良好的可推送性和高抗压性。 切割图案可以包含支撑框架908和环形构件906的轴向连接，这将提供大水平的轴向支撑，侧向柔性和箍强度以抵抗抽吸。 装置的尖端可以包含高度柔性区域905的近端部分907，其可以膨胀至除凝块外。 这种增加身体直径的可能性有助于取回大体积凝块，而导管的构造提供良好的柱刚度以避免轴向坍塌并仍保持良好的柔韧性。

    SYSTEMS AND METHODS FOR MANAGEMENT OF THROMBOSIS
    4.
    发明申请
    SYSTEMS AND METHODS FOR MANAGEMENT OF THROMBOSIS 审中-公开
    用于管理血栓形成的系统和方法

    公开(公告)号：WO2017062927A2

    公开(公告)日：2017-04-13

    申请号：PCT/US2016/056205

    申请日：2016-10-09

    Applicant: INCUVATE, LLC

    Inventor： LOOK, David M. ,  CULBERT, Bradley S.

    IPC: A61B17/22 ,  A61M1/00

    CPC classification number: A61B17/22 ,  A61B17/32037 ,  A61B2017/22054 ,  A61B2017/22067 ,  A61B2017/22079 ,  A61B2017/22084 ,  A61M1/008 ,  A61M2210/12

    Abstract: An aspiration system includes an aspiration catheter including a tubular aspiration member having a proximal end, a distal end, and a lumen, and configured to at least partially extend out of the lumen of an elongate tubular member and into the vasculature of a subject, an elongate support member coupled to the tubular aspiration member and extending between the proximal end of the aspiration catheter and the proximal end of the tubular aspiration member, a high pressure injection lumen extending within the elongate support member and having a distal end including a curved portion configured to change a direction of fluid flow by at least about 90, at least one orifice located at the distal end of the high pressure injection lumen configured to allow liquid to be released into the lumen of the tubular aspiration member, and an annular seal carried by the tubular aspiration member and configured to create a liquid seal against the inner surface of the elongate tubular member.

    Abstract translation: 抽吸系统包括抽吸导管，其包括具有近端，远端和内腔的管状抽吸构件，并且构造成至少部分地延伸出细长管状构件的内腔并进入受试者的脉管系统， 细长的支撑构件，其联接到管状抽吸构件并且在抽吸导管的近端和管状抽吸构件的近端之间延伸;高压注射腔，其在细长支撑构件内延伸并且具有包括弯曲部分的远端，配置 将流体流动的方向改变至少约90°，位于高压注射腔的远端处的至少一个孔被构造成允许液体被释放到管状抽吸构件的内腔中，并且由 管状抽吸构件并且构造成产生抵靠细长管状构件的内表面的液体密封。

    PERFUSION AND FILTER BALLOON
    6.
    发明申请
    PERFUSION AND FILTER BALLOON 审中-公开
    灌注和过滤器气泡

    公开(公告)号：WO2014080425A3

    公开(公告)日：2016-10-06

    申请号：PCT/IN2013000706

    申请日：2013-11-20

    Applicant: ANAND GNANARAJ

    Inventor： ANAND GNANARAJ

    IPC: A61M25/10 ,  A61M29/00

    CPC classification number: A61M25/1002 ,  A61B17/12036 ,  A61B17/12109 ,  A61B17/12136 ,  A61B2017/22067 ,  A61B2017/22097 ,  A61F2/2427 ,  A61F2/958 ,  A61F2002/821 ,  A61M2025/1097

    Abstract: An inflatable blood perfusion and filter balloon for preventing ischaemia is provided. The balloon comprises: a distinctly shaped inflatable chamber with a plurality of wall portions that form a plurality of lumens when inflated, and the lumens cooperatively defining a plurality of outwardly open channels each extending externally lengthwise between the two ends of the inflated balloon for passage of blood, the lumens are formed integrally between the wall portions of the inflated balloon, and the lumens being fitted with a filter which blocks the debris from moving towards the distal vascular bed.

    Abstract translation: 提供了一种用于预防缺血的充气式血液灌注和过滤气囊。 气囊包括：具有多个壁部分的明显形状的可充气室，其在充气时形成多个腔，并且所述腔协作地限定多个向外开放的通道，每个通道在膨胀的气囊的两个端部之间纵向外延伸，以通过 血液，腔体一体地形成在充气球囊的壁部分之间，并且内腔装有过滤器，该过滤器阻挡碎片向远端血管床移动。

    LOW RADIAL FORCE VASCULAR DEVICE AND METHOD OF OCCLUSION
    7.
    发明申请
    LOW RADIAL FORCE VASCULAR DEVICE AND METHOD OF OCCLUSION 审中-公开
    低辐射力血管装置及其消融方法

    公开(公告)号：WO2015187196A1

    公开(公告)日：2015-12-10

    申请号：PCT/US2014/067696

    申请日：2014-11-26

    Applicant: NFINIUM VASCULAR TECHNOLOGIES, LLC

    Inventor： FULTON, Richard, E., III

    IPC: A61M29/00

    CPC classification number: A61B17/1204 ,  A61B17/12109 ,  A61B17/12131 ,  A61B17/12168 ,  A61B17/12172 ,  A61B17/12177 ,  A61B17/221 ,  A61B2017/1205 ,  A61B2017/22038 ,  A61B2017/22067 ,  A61F2/013 ,  A61M29/00

    Abstract: An occlusion apparatus comprises inner and outer sheaths and an expandable flexible tubular sleeve. The occlusion apparatus is advanced to a target site in the blood vessel. A dilator having a soft, compressible tip may be advanced through a lumen of the inner sheath to facilitate the advancement of the occlusion apparatus. The sheaths are translated relative to one another to expand the flexible tubular sleeve to a funnel shape with a distal flush portion contacting the blood vessel inner wall and a proximal tapered portion. The proximal portion is fluid permeable so that blood can pass through to apply pressure on the vessel wall through the distal portion. A capture or traction device can be advanced out of the inner sheath lumen and retracted back therein to capture thrombus. The distal portion of the device may comprise an expandable mesh braid with a memory characteristic to limit expansion.

    Abstract translation: 闭塞装置包括内护套和外护套以及可膨胀的柔性管状套管。 闭塞装置前进到血管中的目标部位。 具有柔软的可压缩末端的扩张器可以通过内护套的内腔前进，以便于闭塞装置的前进。 护套相对于彼此平移以将柔性管状套管膨胀成漏斗形，其中远端冲洗部分接触血管内壁和近端锥形部分。 近端部分是流体可渗透的，使得血液可以通过以通过远端部分在血管壁上施加压力。 捕获或牵引装置可以从内鞘腔中推出并缩回到其中以捕获血栓。 装置的远端部分可以包括具有限制扩张的记忆特性的可扩张网状编织物。

    BLOOD FLOW RESTRICTION APPARATUS AND METHOD FOR EMBOLUS REMOVAL IN HUMAN VASCULATURE
    9.
    发明申请
    BLOOD FLOW RESTRICTION APPARATUS AND METHOD FOR EMBOLUS REMOVAL IN HUMAN VASCULATURE 审中-公开
    血液流量限制装置及其在人体血管中去除血管的方法

    公开(公告)号：WO2014130716A1

    公开(公告)日：2014-08-28

    申请号：PCT/US2014/017469

    申请日：2014-02-20

    Applicant: MA, Jianlu

    Inventor： MA, Jianlu

    IPC: A61M25/04 ,  A61M29/02

    CPC classification number: A61B17/221 ,  A61B17/12036 ,  A61B17/1204 ,  A61B17/12109 ,  A61B17/12172 ,  A61B2017/22067 ,  A61B2017/2212 ,  A61B2017/320716

    Abstract: A mechanical thrombectomy device system is disclosed that is made from a single piece of biocompatible material, including a proximal flow block portion/feature, and/or, a flow block feature in the device body portion, a guidewire like delivery portion and an expandable, treatment portion. The construction of the device from a single piece allows for a seamless transition from the delivery portion to the treatment portion, thus removing any joints or bonding of the two portions together as separate pieces. This improves the strength of the system as a whole and greatly reduces the possibility of the two parts unintentionally detaching from each other. Likewise, the distal treatment portion is cut from a piece of material the same size as the proximal delivery portion, allowing the device to be compacted to a similar size profile giving it delivery advantages including a lower delivery force required and requiring small access systems, and the treatment portion's surface can be altered to enhance embolus affinity by either coating with a substance or changing the texture by mechanical or chemical means.

    Abstract translation: 公开了一种机械性血栓切除装置系统，其由单件生物相容性材料制成，包括近端流动块部分/特征，和/或装置主体部分中的流动块特征，导丝状输送部分和可扩张的， 治疗部分。 从单件构造装置允许从输送部分到处理部分的无缝过渡，从而将两个部分的任何接合部或接合部分一起分离成一体。 这提高了整个系统的强度，并且大大降低了两个部件无意中彼此分离的可能性。 同样地，远端处理部分是从与近端传送部分相同尺寸的一块材料上切割出来的，允许该装置被压实成类似的尺寸轮廓，从而赋予其传送优点，包括所需要的较低的输送力并且需要小的进入系统，以及 治疗部分的表面可以改变以通过用物质涂覆或通过机械或化学方式改变质地来增强栓塞亲和力。

    VASCULAR OCCLUDING DEVICE AND METHODS OF USE
    10.
    发明申请
    VASCULAR OCCLUDING DEVICE AND METHODS OF USE 审中-公开
    血管造影装置及其使用方法

    公开(公告)号：WO2014083559A1

    公开(公告)日：2014-06-05

    申请号：PCT/IL2013/000087

    申请日：2013-12-01

    Applicant: HDH MEDICAL LTD

    Inventor： WAYSBEYN, Igor ,  KAVOUNOVSKI, Irina

    IPC: A61M25/00 ,  A61M25/06 ,  A61B17/12

    CPC classification number: A61B17/1204 ,  A61B17/12045 ,  A61B17/12109 ,  A61B17/12136 ,  A61B2017/22044 ,  A61B2017/22067 ,  A61B2017/22084

    Abstract: The disclosure relates to a vascular device (VOD). More specifically, the disclosure relates to vascular occluding devices having distensible sheath capable of obtaining a prolate spheroid shape having a variable polar axis, with an integral performing tip, capable of effectively temporarily and reversibly occluding fluid flow in body vessels of varying diameters and shapes.

    Abstract translation: 本发明涉及血管装置（VOD）。 更具体地，本公开涉及具有可扩张鞘的血管闭塞装置，其能够获得具有可变极轴的长椭球形，具有整体执行的尖端，能够有效地临时和可逆地阻塞具有不同直径和形状的体液中的流体流动。

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