公开(公告)号：WO2012052006A3

公开(公告)日：2012-08-23

申请号：PCT/DE2011050040

申请日：2011-10-05

Applicant: ACES GMBH ,  TRAUTWEIN FRANK ,  HEUER FRANK ,  FRANKE JOERG ,  KOTHE RALPH ,  LILJENQVIST ULF ,  MATGE GUY ,  PUTZIER MICHAEL

Inventor： TRAUTWEIN FRANK ,  HEUER FRANK ,  FRANKE JOERG ,  KOTHE RALPH ,  LILJENQVIST ULF ,  MATGE GUY ,  PUTZIER MICHAEL

IPC: A61F2/44 ,  A61L27/50 ,  A61L27/56

CPC classification number: A61F2/447 ,  A61F2/30942 ,  A61F2/442 ,  A61F2/4455 ,  A61F2002/30322 ,  A61F2002/30433 ,  A61F2002/30472 ,  A61F2002/30517 ,  A61F2002/30553 ,  A61F2002/30556 ,  A61F2002/30563 ,  A61F2002/30576 ,  A61F2002/30579 ,  A61F2002/30593 ,  A61F2002/30596 ,  A61F2002/30598 ,  A61F2002/30601 ,  A61F2002/30604 ,  A61F2002/30616 ,  A61F2002/30622 ,  A61F2002/30668 ,  A61F2002/30736 ,  A61F2002/30784 ,  A61F2002/30892 ,  A61F2002/30904 ,  A61F2002/3092 ,  A61F2002/30925 ,  A61F2002/3093 ,  A61F2002/3097 ,  A61F2002/30971 ,  A61F2002/30976 ,  A61F2002/30978 ,  A61F2002/4475 ,  A61F2002/448 ,  A61F2002/482 ,  A61L27/04 ,  A61L27/14 ,  A61L2430/38

Abstract: The application relates to a spinal implant composed of a plurality of parallel plates. The deliberate introduction of contours in the plates allows for the creation of biomechanically advantageous functions and adjustment options. The elasticity of the anchoring elements enables the disclosed implant to be adjusted to the osseous endplates, resulting in uniform force distribution and thus prevention of the risk of compaction or endplate compression fracture. The plate structure allows for the use of production methods in which hook-like undercut contours can be created, thus enabling the implant to be anchored in the bone without causing damage thereto. Furthermore, the plates can be interconnected by an actuator in such a way that the height and/or the angular position can be adjusted, thus enabling the intervertebral disk space to be vertically and physically adjusted. The vertical adjustment can vary along the length of the implant such that the segment can also be angularly adjusted. If the plates are interconnected by an eccentric shaft, the combined vertical and translational movement to which the set of plates is subjected can also be used to translationally reposition two vertebrae.

Abstract translation: 该申请涉及一种脊柱植入物，其由多个平行板构成。 通过在板中的有针对性地引入轮廓的生物力学有利的功能和设置都可以生产。 因此，植入物可以以确保力的均匀分布，并对抗Einsinterung的风险或盖板入室通过锚固元件到骨盖板的弹性适应。 由面板组件的制造方法可用于使生产钩状底切轮廓，从而锚定在骨，而不允许此损坏。 此外，该板可以通过致动器，因为它们可以在高度和/或以一角度来调整这样的方式连接，从而允许勃起和椎间盘空间的生理调节。 勃起可以在植入物的长度不同，从而使该段的角度调整是可能的。 经由连接到彼此的偏心轴，以便施加到复合板组合提升和平移运动的力的板也可以用于两个椎骨的平移重新定位。

公开(公告)号：WO2003013396A1

公开(公告)日：2003-02-20

申请号：PCT/GB2002/003723

申请日：2002-08-12

Applicant: STANMORE IMPLANTS WORLDWIDE LTD. ,  UNWIN, Paul ,  BLUNN, Gordon ,  JACOBS, Michael, Herbert ,  ASHWORTH, Mark, Andrew ,  WU, Xinhua

Inventor： UNWIN, Paul ,  BLUNN, Gordon ,  JACOBS, Michael, Herbert ,  ASHWORTH, Mark, Andrew ,  WU, Xinhua

IPC: A61F2/30

CPC classification number: A61L27/56 ,  A61F2/3094 ,  A61F2/44 ,  A61F2/442 ,  A61F2/447 ,  A61F2002/30011 ,  A61F2002/30013 ,  A61F2002/30112 ,  A61F2002/30133 ,  A61F2002/30153 ,  A61F2002/30224 ,  A61F2002/30448 ,  A61F2002/30769 ,  A61F2002/30777 ,  A61F2002/30785 ,  A61F2002/3081 ,  A61F2002/30968 ,  A61F2002/3097 ,  A61F2002/30978 ,  A61F2002/4475 ,  A61F2220/005 ,  A61F2230/0004 ,  A61F2230/0015 ,  A61F2230/0019 ,  A61F2230/0069 ,  A61F2250/0023 ,  A61F2250/0024 ,  A61F2310/00017 ,  A61F2310/00023 ,  A61F2310/00029 ,  A61F2310/00856 ,  A61F2310/0088 ,  A61L27/045 ,  A61L27/047 ,  A61L27/06 ,  B33Y80/00 ,  Y10T428/12993

Abstract: A surgical implant comprises a core region and a porous surface region extending over at least a part of said core region. The porous surface region has a predetermined pore volume fraction. A method of manufacturing a surgical implant in accordance with the invention comprises the steps of: (i) loading metallic powder having a predetermined particle size distribution around a pre-formed core in a sealable capsule; (ii) reducing pressure within said capsule to a predetermined pressure below atmospheric pressure; (iii) pressurising said capsule with a process gas to a predetermined pressure higher than the predetermined pressure of step (ii); (iv) sealing said capsule; (v) heating said pressurised sealed capsule at an elevated temperature and an elevated pressure for a predetermined time to produce an implant precursor; (vi) cooling said sealed capsule, and; (vii) heating said implant precursor for a predetermined time at an elevated temperature and a predetermined pressure below atmospheric pressure, whereby to generate porosity in said implant precursor.

Abstract translation: 手术植入物包括芯区域和在所述芯区域的至少一部分上延伸的多孔表面区域。 多孔表面区域具有预定的孔体积分数。 根据本发明的制造手术植入物的方法包括以下步骤：（i）将预定粒度分布的金属粉末装载在可密封胶囊内的预先形成的芯部周围; （ii）将所述胶囊内的压力降低至低于大气压的预定压力; （iii）用处理气体将所述胶囊加压至高于步骤（ii）的预定压力的预定压力; （iv）密封所述胶囊; （v）在升高的温度和升高的压力下加热所述加压的密封胶囊一段预定的时间以产生植入物前体; （vi）冷却所述密封胶囊， （vii）在升高的温度和低于大气压的预定压力下将所述植入物前体加热预定时间，从而在所述植入物前体中产生孔隙。

公开(公告)号：WO99037241A3

公开(公告)日：1999-12-09

申请号：PCT/US1999/001357

申请日：1999-01-22

IPC: A61B17/06 ,  A61B17/80 ,  A61B17/82 ,  A61B17/84 ,  A61F2/00 ,  A61F2/08 ,  A61F2/28 ,  A61F2/30 ,  A61F2/36 ,  A61F2/46 ,  B23H1/04 ,  B23H9/00 ,  B23H1/00

CPC classification number: B23H1/04 ,  A61B17/06166 ,  A61B17/809 ,  A61B17/82 ,  A61B17/842 ,  A61F2/0811 ,  A61F2/30739 ,  A61F2/30771 ,  A61F2/3094 ,  A61F2/3607 ,  A61F2/367 ,  A61F2002/2835 ,  A61F2002/30112 ,  A61F2002/30143 ,  A61F2002/30153 ,  A61F2002/302 ,  A61F2002/30322 ,  A61F2002/30332 ,  A61F2002/30367 ,  A61F2002/30382 ,  A61F2002/30405 ,  A61F2002/30434 ,  A61F2002/30443 ,  A61F2002/30604 ,  A61F2002/30784 ,  A61F2002/30795 ,  A61F2002/30797 ,  A61F2002/30808 ,  A61F2002/30841 ,  A61F2002/30892 ,  A61F2002/30957 ,  A61F2002/30978 ,  A61F2002/3625 ,  A61F2002/365 ,  A61F2002/3674 ,  A61F2002/368 ,  A61F2002/4638 ,  A61F2220/0025 ,  A61F2220/0033 ,  A61F2220/0041 ,  A61F2230/0004 ,  A61F2230/0017 ,  A61F2230/0019 ,  A61F2230/0065 ,  A61F2250/0026 ,  B23H9/008

Abstract: An implantable orthopedic prosthesis (10) has a macro/micro-textured bone and soft tissue attachment surface (34) to which a spiked washer (40) is clamped by a threaded bolt (46) received through said washer (40) and threaded into said prosthesis (10). Soft tissue is secured to the prosthesis (10) by clamping between said washer (40) and said soft tissue attachment surface. The tissue attachment surface is arranged as a regular grid of depressions (36) separated by orthogonal ridges (38) formed by electrodischarge machining of the prosthesis using a machining electrode (56) having a mold-opposite surface texture with a micro-textured roughened surface finish. The spacing (X2) of the spikes (42) is an integer multiple of the spacing (X1) of the depressions (36) to assure registry of the spikes (42) with the depressions (36).

Abstract translation: 可植入矫形假体（10）具有宏/微纹理的骨骼和软组织附着表面（34），加标垫圈（40）由穿过所述垫圈（40）的螺栓（46）夹紧到所述表面上并拧入 所述假体（10）。 软组织通过在所述垫圈（40）和所述软组织附接表面之间夹紧固定到所述假体（10）上。 组织附着表面被布置为通过使用具有与微细纹理粗糙表面的模具相对表面纹理的加工电极（56）形成的通过对所述假体的放电加工形成的正交脊（38）分开的凹陷（36）的规则格栅 完。 尖峰（42）的间距（X2）是凹部（36）的间隔（X1）的整数倍，以确保尖峰（42）与凹陷（36）的对准。

公开(公告)号：WO9937241A2

公开(公告)日：1999-07-29

申请号：PCT/US9901357

申请日：1999-01-22

Applicant: SULZER ORTHOPEDICS INC

Inventor： BROWN STEVE ,  WHEELER JOHN ,  LESTER MARK ,  BURROWS JAMES

IPC: A61B17/06 ,  A61B17/80 ,  A61B17/82 ,  A61B17/84 ,  A61F2/00 ,  A61F2/08 ,  A61F2/28 ,  A61F2/30 ,  A61F2/36 ,  A61F2/46 ,  B23H1/04 ,  B23H9/00

CPC classification number: B23H1/04 ,  A61B17/06166 ,  A61B17/809 ,  A61B17/82 ,  A61B17/842 ,  A61F2/0811 ,  A61F2/30739 ,  A61F2/30771 ,  A61F2/3094 ,  A61F2/3607 ,  A61F2/367 ,  A61F2002/2835 ,  A61F2002/30112 ,  A61F2002/30143 ,  A61F2002/30153 ,  A61F2002/302 ,  A61F2002/30322 ,  A61F2002/30332 ,  A61F2002/30367 ,  A61F2002/30382 ,  A61F2002/30405 ,  A61F2002/30434 ,  A61F2002/30443 ,  A61F2002/30604 ,  A61F2002/30784 ,  A61F2002/30795 ,  A61F2002/30797 ,  A61F2002/30808 ,  A61F2002/30841 ,  A61F2002/30892 ,  A61F2002/30957 ,  A61F2002/30978 ,  A61F2002/3625 ,  A61F2002/365 ,  A61F2002/3674 ,  A61F2002/368 ,  A61F2002/4638 ,  A61F2220/0025 ,  A61F2220/0033 ,  A61F2220/0041 ,  A61F2230/0004 ,  A61F2230/0017 ,  A61F2230/0019 ,  A61F2230/0065 ,  A61F2250/0026 ,  B23H9/008

Abstract: An implantable orthopedic prosthesis (10) has a macro/micro-textured bone and soft tissue attachment surface (34) to which a spiked washer (40) is clamped by a threaded bolt (46) received through said washer and threaded into said prosthesis. Soft tissue is secured to the prosthesis by clamping between said washer and said soft tissue attachment surface. The tissue attachment surface is arranged as a regular grid of depressions (36) separated by orthogonal ridges (38) formed by electrodischarge machining of the prosthesis using a machining electrode (56) having a mold-opposite surface texture with a micro-textured roughened surface finish. The spacing of the spikes is an integer multiple of the spacing of the depressions to assure registry of the spikes with the depressions.

Abstract translation: 可植入矫形假体（10）具有宏/微纹理的骨和软组织附着表面（34），加标垫圈（40）由穿过所述垫圈并穿入所述假体的螺纹螺栓（46）夹紧到所述表面。 软组织通过夹紧在所述垫圈和所述软组织附接表面之间固定到假体上。 组织附着表面被布置为通过使用具有与微细纹理粗糙表面的模具相对表面纹理的加工电极（56）形成的通过对所述假体进行电放电加工而形成的正交脊（38）分开的凹陷（36）的规则格栅 完。 尖峰的间距是凹陷间距的整数倍，以确保峰值与凹陷的注册。

公开(公告)号：WO2015048997A1

公开(公告)日：2015-04-09

申请号：PCT/EP2013/070589

申请日：2013-10-02

Applicant: VIGAS

Inventor： MESDOM, Steven ,  SIAU, Vincent

IPC: A61F2/44

CPC classification number: A61F2/447 ,  A61F2002/30604 ,  A61F2002/30612 ,  A61F2002/30827 ,  A61F2002/30838 ,  A61F2002/3084 ,  A61F2002/3092 ,  A61F2002/30978 ,  A61F2002/3098 ,  A61F2002/30981 ,  A61F2002/4475 ,  A61F2002/4485 ,  A61F2310/00131 ,  A61F2310/00227 ,  A61F2310/00401 ,  A61F2310/00407 ,  A61F2310/00431 ,  A61F2310/00443 ,  A61F2310/00544 ,  A61F2310/00796

Abstract: A spinal implant (1, 5, 6) for positioning in between two vertebrae, comprising a substrate (16) and at least one integration layer (17) at an outer surface of the spinal implant for facilitating the acceptance of said implant by the human body, the substrate (16) of the implant being formed of a biocompatible polymer material and comprising at its outer surface the integration layer (17), the spinal implant having a texture in which the distance between adjacent local extrema is less than 1 mm, wherein the integration layer (17) is in the form of a coating applied onto the substrate (16).

Abstract translation: 一种用于定位在两个椎骨之间的脊椎植入物（1,5,6），包括基底（16）和位于脊柱植入物的外表面处的至少一个集成层（17），用于促进 由人体接受所述植入物，植入物的基底（16）由生物相容性聚合物材料形成并且在其外表面包括整合层（17），所述脊柱植入物具有纹理，其中相邻 局部极值小于1mm，其中整合层（17）为涂覆在基底（16）上的涂层形式。

公开(公告)号：WO2004000174A1

公开(公告)日：2003-12-31

申请号：PCT/US2003/019578

申请日：2003-06-20

Applicant: MEDICAL CARBON RESEARCH INSTITUTE ,  BOKROS, Jack, C. ,  MORE, Robert, B. ,  ACCUNTIUS, James, A.

Inventor： BOKROS, Jack, C. ,  MORE, Robert, B. ,  ACCUNTIUS, James, A.

IPC: A61F2/36

CPC classification number: A61M39/0247 ,  A61F2/2403 ,  A61F2/30767 ,  A61F2/3099 ,  A61F2/34 ,  A61F2/38 ,  A61F2/3804 ,  A61F2/40 ,  A61F2/4202 ,  A61F2/4225 ,  A61F2/4241 ,  A61F2/442 ,  A61F2002/30225 ,  A61F2002/30233 ,  A61F2002/30322 ,  A61F2002/30535 ,  A61F2002/30878 ,  A61F2002/3092 ,  A61F2002/30922 ,  A61F2002/30934 ,  A61F2002/30978 ,  A61F2002/3611 ,  A61F2002/3827 ,  A61F2002/3831 ,  A61F2002/4248 ,  A61F2002/4251 ,  A61F2230/0069 ,  A61F2250/0026 ,  A61F2250/0058 ,  A61F2310/00131 ,  A61F2310/00574 ,  A61L27/303 ,  A61L27/306 ,  A61L27/56 ,  A61M2039/025

Abstract: A bone implant (71) comprises a body formed of an articulated open cell structure of a lightweight material, the surfaces of which structure are covered with a thin metal layer. A layer of biocompatible pyrocarbon coating is applied to the metal-coated structure so as to cover the entire structure and provide a dense, nonporous, biocompatible layer. Pyrocarbon is then selectively removed from portions (73) of the surface of the body to expose sections of the original surface which lead to regions of interconnected channels into which bone and tissue ingrowth are promoted while end regions (75) and (77) remain totally covered with such pyrocarbon.

Abstract translation: 骨植入物（71）包括由轻质材料的铰接的开放式细胞结构形成的主体，其表面被薄金属层覆盖。 将一层生物相容的热解碳涂层施加到金属涂覆的结构上，以覆盖整个结构并提供致密，无孔的生物相容性层。 然后从身体表面的部分（73）选择性地去除焦炭，以暴露出原始表面的部分，这些部分导致相互沟通的区域，骨骼和组织向内生长被促进，其中端部区域（75）和（77）保持完全 覆盖着这样的热解碳。

公开(公告)号：WO1997036708A1

公开(公告)日：1997-10-09

申请号：PCT/NZ1997000044

申请日：1997-04-02

Applicant: INDUSTRIAL RESEARCH LIMITED ,  ANDERSON, Ian, Alexander ,  CLARK, Harry, Christopher ,  SULLIVAN, John, Martin, Patrick ,  WYATT, Timothy, Peter

Inventor： INDUSTRIAL RESEARCH LIMITED

IPC: B23H09/00

CPC classification number: A61F2/30771 ,  A61F2/30942 ,  A61F2002/30113 ,  A61F2002/30156 ,  A61F2002/30224 ,  A61F2002/30892 ,  A61F2002/30957 ,  A61F2002/30978 ,  A61F2230/0006 ,  A61F2230/0023 ,  A61F2230/0069 ,  A61L27/04 ,  B23H1/04

Abstract: A spark erosion electrode (1) can create a contoured surface to facilitate the growth and adhesion of bone tissue on the surface. The electrode (1) includes a collection of parallel electrode members (10), which are preferably tubular. These members (10) are held by a releasable clamp (2) such that they can be moved axially whereby ends of the members (10) can form a negative pattern of a required contour which can then be replicated on the surface of an object such as that of a bone implant.

Abstract translation: 火花腐蚀电极（1）可以产生轮廓表面以促进骨组织在表面上的生长和粘附。 电极（1）包括平行电极构件（10）的集合，其优选地是管状的。 这些构件（10）由可释放的夹具（2）保持，使得它们可以轴向移动，从而构件（10）的端部可以形成所需轮廓的负图形，然后可以在物体的表面上复制 如同骨植入物一样。

公开(公告)号：WO1992000046A1

公开(公告)日：1992-01-09

申请号：PCT/US1991002542

申请日：1991-04-12

Applicant: PFIZER HOSPITAL PRODUCTS GROUP, INC.

Inventor： PFIZER HOSPITAL PRODUCTS GROUP, INC. ,  GUSTAVSON, Larry, J.

IPC: A61F02/30

CPC classification number: A61F2/30907 ,  A61F2/30734 ,  A61F2/367 ,  A61F2/389 ,  A61F2002/30009 ,  A61F2002/30112 ,  A61F2002/30156 ,  A61F2002/30451 ,  A61F2002/30454 ,  A61F2002/30599 ,  A61F2002/30733 ,  A61F2002/30777 ,  A61F2002/30805 ,  A61F2002/30909 ,  A61F2002/30915 ,  A61F2002/30925 ,  A61F2002/30967 ,  A61F2002/3097 ,  A61F2002/30976 ,  A61F2002/30978 ,  A61F2002/3682 ,  A61F2220/0058 ,  A61F2230/0004 ,  A61F2230/0023 ,  A61F2250/0028 ,  A61F2250/0063 ,  A61F2310/00023

Abstract: A prosthetic part (10) for use as an orthopedic implant has a base member defining an outer surface (20) for implantation adjacent a prepared bone surface (21). The outer surface (20) includes a recessed area (16) having a predetermined shape and depth. A first rigid plate (22) having this predetermined shape and having a plurality of elongated slots (26) formed therein is fixedly attached within the recessed area (16) of the base member. A second rigid plate (24) also having the same predetermined shape as the recess and also having a plurality of elongated slots (28) formed therein is attached to the first rigid plate. The elongated slots (28) of the second plate (24) are angularly offset with respect to the elongated slots (26) in the first plate to produce a controlled porosity. The thicknesses of the first and second plates are predetermined so that the outer surface (18) of the second plate is substantially continuous with the non-recessed outer surface (20) of the base member (10).

公开(公告)号：WO2015049222A1

公开(公告)日：2015-04-09

申请号：PCT/EP2014/070902

申请日：2014-09-30

Applicant: VIGAS

Inventor： MESDOM, Steven ,  SIAU, Vincent

IPC: A61F2/44

CPC classification number: A61F2/447 ,  A61F2002/30604 ,  A61F2002/30612 ,  A61F2002/30827 ,  A61F2002/30838 ,  A61F2002/3084 ,  A61F2002/3092 ,  A61F2002/30978 ,  A61F2002/3098 ,  A61F2002/30981 ,  A61F2002/4475 ,  A61F2002/4485 ,  A61F2310/00131 ,  A61F2310/00227 ,  A61F2310/00401 ,  A61F2310/00407 ,  A61F2310/00431 ,  A61F2310/00443 ,  A61F2310/00544 ,  A61F2310/00796

Abstract: A spinal implant (1, 5, 6) for positioning in between two vertebrae, comprising a substrate (16) and at least one integration layer (17) at an outer surface of the spinal implant for facilitating the acceptance of said implant by the human body, the substrate (16) of the implant being formed of a biocompatible polymer material and comprising at its outer surface the integration layer (17), the spinal implant having a texture in which the distance between adjacent local extrema is less than 1 mm, wherein the integration layer (17) is in the form of a coating applied onto the substrate (16).

Abstract translation: 一种用于定位在两个椎骨之间的脊椎植入物（1,5,6），其包括在所述脊柱植入物的外表面处的基底（16）和至少一个整合层（17），以便于人接受所述植入物 植入物的基底（16）由生物相容的聚合物材料形成并且在其外表面处包含整合层（17），脊柱植入物具有其中相邻局部极值之间的距离小于1mm的纹理， 其中所述积分层（17）是施加到所述基底（16）上的涂层的形式。

公开(公告)号：WO2015022039A1

公开(公告)日：2015-02-19

申请号：PCT/EP2014/001719

申请日：2014-06-25

Applicant: JOIMAX GMBH

Inventor： RIES, Wolfgang

IPC: A61F2/44 ,  A61F2/46 ,  A61F2/30

CPC classification number: A61F2/4455 ,  A61F2/30771 ,  A61F2/442 ,  A61F2/447 ,  A61F2/4611 ,  A61F2002/30454 ,  A61F2002/30523 ,  A61F2002/30598 ,  A61F2002/30607 ,  A61F2002/30777 ,  A61F2002/30779 ,  A61F2002/30784 ,  A61F2002/30785 ,  A61F2002/30789 ,  A61F2002/30831 ,  A61F2002/30843 ,  A61F2002/30909 ,  A61F2002/30911 ,  A61F2002/30912 ,  A61F2002/3093 ,  A61F2002/30968 ,  A61F2002/3097 ,  A61F2002/30978 ,  A61F2002/4475 ,  A61F2002/4495 ,  A61F2002/4627 ,  A61F2310/00023 ,  A61F2310/00047

Abstract: Es wird ein Zwischenwirbel-Körbchen (5) vorgeschlagen, das zum besseren Verbinden/Verwachsen in den Wirbelbereich (3, 4) netz- oder gitterformige Bereiche aufweist. Das Körbchen hat insbesondere einen äußeren Rahmen, der aus massiven Tragteilen besteht und einen inneren Gitterkörper. Der die äußere Kontur bestimmende Rahmen und die innerhalb desselben befindliche Netz- oder Gitterbereiche sind einstückig ausgebildet. Das Körbchen ist durch Sintern, wie mittels Elektronenstrahlschmelzen oder Lasersintern hergestellt.

Abstract translation: 它提出了一种具有改进的接合/聚结的椎间杯（5）（3，4），网或网格状在涡流区域的区域。 所述篮具有特别的外框架，它由大量的支承部分和一内栅格体的。 外轮廓框架和位于内相同的确定所述网络或光栅区域一体地形成。 篮筐通过烧结制成，例如通过电子束熔炼或激光烧结。