摘要:
Fixating or fusing a first and second bone segments separated by a fracture line or joint by creating an insertion path through the first bone segment, through the fracture or joint, and into the second bone segment and inserting an anchor body that is anchored at the distal end within the second bone segment. An elongated implant structure passes over the anchor body to span the fracture or joint between the bone segments. The proximal end of the anchor body is anchored on the exterior of the first bone segment and places the anchor body and bone segments in compression.
摘要:
A tissue scaffold fabricated from bioinert fiber forms a rigid three-dimensional porous matrix having a bioinert composition. Porosity in the form of interconnected pore space is provided by the space between the bioinert fiber in the porous matrix. Strength of the porous matrix is provided by bioinert fiber fused and bonded into the rigid three-dimensional matrix having a specific pore size and pore size distribution. The tissue scaffold supports tissue in¬ growth to provide osteoconductivity as a tissue scaffold, used for the repair of damaged and/ or diseased bone tissue.
摘要:
A method of making an injectable or implantable active agent delivery device capable of delivering a diagnostic, therapeutic, and/or prophylactic agent to a desired targeted site having orifice(s) on the surface is disclosed herein providing unidirectional release of the agent at a controlled desirable rate. The agent may include, but is not limited to, drugs, proteins, peptides, biomarkers, bioanalytes, and/or genetic material. The technology of the invention is based on parallel processing to fabricate micro-holes on tubes employing photo-lithography and reactive ion etching techniques and also incorporates a simple molding method to form the micro-holes on flexible polymer tubes, including bio-degradable tubes. The parallel processing method of the instant invention is fast, economical and well suited for mass production. The developed device, due to its composite structure, has the ability to combine several release mechanisms, leading to zero-order release kinetics for most of the time.
摘要:
A scaffold for implantation into a mammal to facilitate vessel growth in repair, regeneration, and/or proliferation of bodily tissue, where the scaffold is based on a borate, silicate, or phosphate, glass-former and is biodegradable upon implantation in mammals. The scaffold includes one or more trace elements from the group consisting of Cu, F, Fe, Mn, Mo, Ni, Sr, and Zn which are released into the host to support vessel growth. A method involves implantation of such scaffolds.
摘要:
Systems and methods for providing deeper knee flexion capabilities, more physiologic load bearing and improved patellar tracking for knee prosthesis patients. Such systems and methods include (i) adding more articular surface to the antero- proximal posterior condyles of a femoral component, including methods to achieve that result, (ii) modifications to the internal geometry of the femoral component and the associated femoral bone cuts with methods of implantation, (iii) asymmetrical tibial components that have an unique articular surface that allows for deeper knee flexion than has previously been available, (iv) asymmetrical femoral condyles that result in more physiologic loading of the joint and improved patellar tracking and (v) modifying an articulation surface of the tibial component to include an articulation feature whereby the articulation pathway of the femoral component is directed or guided by articulation feature.
摘要:
An intervertebral implant (300) for insertion into an intervertebral disc space between adjacent vertebral bodies or between two bone portions. The implant includes a spacer portion (310), a plate portion (330) operatively coupled to the spacer portion and one or more blades (350) for securing the implant to the adjacent vertebral bodies. The blades preferably include superior and inferior cylindrical pins (360) for engaging the adjacent vertebral bodies. The implant may be configured to be inserted via a direct lateral transposals approach. Alternatively, the implant may be configured for insertion via an anterior approach.
摘要:
Joint space interpositional prosthetic devices for positioning between surfaces of a joint in a patient are disclosed. The prosthetic device may have exterior surfaces (24, 26) affixed to the joint surfaces and may have internal surfaces (32, 34) which provide bearing surfaces. In an exemplary embodiment, the bearing surfaces are encapsulated within the device. The exterior surfaces of the device may include bone securement features to facilitate attachment of the prosthetic device to the joint surfaces.
摘要:
Joint space interpositional prosthetic devices for positioning between surfaces of a joint in a patient are disclosed. The prosthetic device may have exterior surfaces affixed to the joint surfaces and may have internal surfaces which provide bearing surfaces. In an exemplary embodiment, the bearing surfaces are encapsulated within the device. The exterior surfaces of the device may include bone securement features to facilitate attachment of the prosthetic device to the joint surfaces.
摘要:
Systems are provided for reducing the complexity and invasiveness of spinal stabilization procedures and provide an expandable device (20, 50, 90, 120, 220, 300, 320, 350, 360, 420, 420', 490, 520) deliverable to a spinal implantation location. The expandable device can be delivered through a minimally invasive access portal and expanded at the implantation location to manipulate one or more bony structures or maintain a configuration of one or more bony structures.