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    CASCADE IMPACTOR PLATE COATING
    2.
    发明申请
    CASCADE IMPACTOR PLATE COATING 审中-公开

    公开(公告)号：WO2017121996A1

    公开(公告)日：2017-07-20

    申请号：PCT/GB2017/050047

    申请日：2017-01-10

    Applicant: KIND CONSUMER LIMITED

    Inventor： SILCOCK, Alan James

    IPC: G01N15/02 ,  G01N1/22 ,  B01D1/00 ,  B01B1/00 ,  A61K31/465 ,  B01D45/08

    CPC classification number: G01N15/0255 ,  A61K31/465 ,  G01N2001/2223 ,  G01N2015/0026 ,  G01N2015/0261

    Abstract: The present invention relates to a cascade impactor for measuring particle size distribution of an aerosol comprising nicotine, the cascade impactor comprising: an induction port for receiving an inhaler; and at least one sample collection stage comprising a nozzle assembly and a collection means; wherein the collection means of at least one sample collection stage is coated with isopropyl alcohol.

    Abstract translation: 本发明涉及用于测量包含尼古丁的气雾剂的粒度分布的级联冲击器，所述级联冲击器包括：用于接收吸入器的吸入口; 以及至少一个样品收集台，其包括喷嘴组件和收集装置; 其中至少一个样品收集阶段的收集装置涂覆有异丙醇。

    NICOTINE REPLACEMENT THERAPY PRODUCTS COMPRISING SYNTHETIC NICOTINE
    3.
    发明申请
    NICOTINE REPLACEMENT THERAPY PRODUCTS COMPRISING SYNTHETIC NICOTINE 审中-公开
    包含合成尼古丁的NICOTINE替代疗法产品

    公开(公告)号：WO2017117575A1

    公开(公告)日：2017-07-06

    申请号：PCT/US2016/069593

    申请日：2016-12-30

    Applicant: NEXT GENERATION LABS, LLC

    Inventor： ARNOLD, Michael

    IPC: A24B15/16 ,  A24B15/00 ,  A24D1/18 ,  A24F47/00

    CPC classification number: A61K31/465 ,  A24F47/002 ,  A61K9/0058 ,  A61K9/006 ,  A61K9/7023 ,  A61M11/00 ,  C07D401/04

    Abstract: A composition suitable for use in nicotine replacement therapy products includes a nicotine product that includes a synthetic nicotine that is substantially free of one or more contaminants and/or impurities normally associated with tobacco-derived nicotine. For example, the synthetic nicotine is substantially free of one or more of nicotine-1'-N-oxide, nicotyrine, nornicotyrine, 2',3-bipyridyl, cotinine, anabasine, and/or anatabine. The composition further comprises one or more pharmaceutically acceptable excipients, additives and/or carriers. The nicotine replacement therapy products may include any number of such products, including transdermal nicotine delivery patches, nicotine gums, synthetic chewing tobacco, synthetic snuff, and synthetic strips (e.g., dissolvable synthetic tobacco). Additionally, a method of treating nicotine addiction includes administering a nicotine replacement composition, e.g., via a nicotine replacement therapy product, to a user.

    Abstract translation: 适合用于尼古丁替代疗法产品的组合物包括尼古丁产品，其包含基本上不含一种或多种通常与烟草来源的尼古丁相关的污染物和/或杂质的合成尼古丁。 例如，合成尼古丁基本上不含烟碱-1'-N-氧化物，烟碱，去腐基烟碱，2'，3-联吡啶，可替宁，阿那巴生和/或新烟草碱中的一种或多种。 该组合物还包含一种或多种药学上可接受的赋形剂，添加剂和/或载体。 尼古丁替代疗法产品可以包括任何数量的此类产品，包括透皮尼古丁递送贴剂，尼古丁胶，合成嚼烟草，合成鼻烟和合成条（例如可溶性合成烟草）。 另外，治疗尼古丁成瘾的方法包括给予使用者尼古丁替代组合物，例如通过尼古丁替代疗法产品。

    CHEWABLE MEDICAMENT
    5.
    发明申请
    CHEWABLE MEDICAMENT 审中-公开
    可燃药物

    公开(公告)号：WO2017042592A1

    公开(公告)日：2017-03-16

    申请号：PCT/GB2016/052816

    申请日：2016-09-12

    Applicant: REVOLYMER (U.K.) LIMITED

    Inventor： OSBORNE, Victoria Lee ,  BEKKAOUI, Ali

    IPC: A61K9/68 ,  A61K31/465

    CPC classification number: A61K9/0058 ,  A61K31/465

    Abstract: Chewing gum compositions comprising a biologically active ingredients are described, in which the gum compositions have a compression modulus of less than 7 kPa. The gums of the invention exhibit improved patient compliance when compared with prior art gums, as well as offering improved release characteristics of the active ingredient contained therein.

    Abstract translation: 描述了包含生物活性成分的口香糖组合物，其中口香糖组合物的压缩模量小于7kPa。 与现有技术的牙龈相比，本发明的牙龈表现出改进的患者顺应性，并且提供其中包含的活性成分的改善的释放特性。

    METHODS FOR TREATING DISORDERS ASSOCIATED WITH UNDESIRED ACTIVITY OF NEURONAL NICOTINIC ACETYLCHOLINE RECEPTORS
    9.
    发明申请
    METHODS FOR TREATING DISORDERS ASSOCIATED WITH UNDESIRED ACTIVITY OF NEURONAL NICOTINIC ACETYLCHOLINE RECEPTORS 审中-公开
    治疗与神经激动素乙酰胆碱受体无活性相关的疾病的方法

    公开(公告)号：WO2016134019A1

    公开(公告)日：2016-08-25

    申请号：PCT/US2016/018273

    申请日：2016-02-17

    Applicant: DEMERX, INC.

    Inventor： MAILLET, Emeline

    IPC: A61K31/00 ,  A61K31/33 ,  A61K31/395 ,  A61K31/55

    CPC classification number: A61K31/465

    Abstract: This invention is directed to a method of treating one or more disorders associated with an undesired downstream activity of at least one subtype of neuronal nicotinic acetylcholine receptor, comprising treating a patient with noribogaine, noribogaine derivative, or pharmaceutically acceptable salt or solvate thereof so as to attenuate said undesired effect.

    Abstract translation: 本发明涉及一种治疗与神经元烟碱乙酰胆碱受体的至少一种亚型的不期望的下游活性相关的一种或多种病症的方法，其包括用维生素，诺维伯因衍生物或其药学上可接受的盐或溶剂化物治疗患者，以便 衰减所述不期望的效果。

    멜라토닌을 포함하는 안정성이 개선된 육모, 양모 또는 발모 촉진용 조성물
    10.
    发明申请
    멜라토닌을 포함하는 안정성이 개선된 육모, 양모 또는 발모 촉진용 조성물 审中-公开
    用于头发健康或头发生长促进的组合物，具有改善的稳定性和包含MELATONIN

    公开(公告)号：WO2016122172A1

    公开(公告)日：2016-08-04

    申请号：PCT/KR2016/000742

    申请日：2016-01-22

    Applicant: 현대약품 주식회사

    Inventor： 이풍석 ,  이동일 ,  전예지 ,  유영근

    IPC: A61K31/4045 ,  A61K31/465 ,  A61K31/415

    CPC classification number: A61K31/4045 ,  A61K31/415 ,  A61K31/465

    Abstract: 본 발명은 멜라토닌, 덱스판테놀, 비오틴 및 니코틴산아미드를 유효성분으로 포함하는 육모, 양모 또는 발모 촉진용 약제학적 조성물에 관한 것이다. 본 발명의 조성물은 약리 활성성분인 멜라토닌의광안정성을 개선하면서 제제를 안정화시키고 두피 염증을 유의하게 억제함으로써, 발모 또는 양모 효과를 극대화시킨다. 따라서, 본 발명의 조성물은 광안정성, 보존성, 투약 편의성 및 치료효과가 동시에 증대된 효율적인 발모, 양모 촉진제 또는 탈모의 예방 또는 치료제로서 유용하게 이용될 수 있다.

    Abstract translation: 本发明涉及一种含有褪黑激素，右旋苯酚，生物素和烟酰胺作为活性成分的头发健康或毛发生长促进用药物组合物。 本发明的组合物通过使制剂稳定化，同时提高作为药理活性成分的褪黑激素的光稳定性，显着抑制头皮炎症，使头发生长发育或毛发健康效果最大化。 因此，本发明的组合物可用作有效的毛发生长或毛发健康促进剂或用作预防或治疗脱发的药剂，该组合物同时提高光稳定性，保存性，给药方便性和治疗效果。

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