利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

28 条记录 (耗时 0.016 秒)

    C-CHANNEL TO O-CHANNEL CONVERTER FOR A SINGLE OPERATOR EXCHANGE BILIARY CATHETER
    3.
    发明申请
    C-CHANNEL TO O-CHANNEL CONVERTER FOR A SINGLE OPERATOR EXCHANGE BILIARY CATHETER 审中-公开
    用于单个操作员交换双通道的C通道到O通道转换器

    公开(公告)号：WO2002078776A2

    公开(公告)日：2002-10-10

    申请号：PCT/US2002/004647

    申请日：2002-02-19

    申请人： SCIMED LIFE SYSTEMS, INC.

    发明人： RICHARDSON, Kevin ,  MANGANO, Michael

    IPC分类号： A61M25/00

    CPC分类号： A61M25/0029 ,  A61M25/0023 ,  A61M25/0032 ,  A61M2025/018 ,  A61M2025/0183 ,  A61M2025/09125 ,  A61M2025/1056 ,  A61M2210/1071 ,  A61M2210/1075

    摘要： A catheter system for use during biliary procedures, including a first elongate member carrying a guidewire lumen, and a channel extending longitudinally along the member wich provides access to the guidewire lumen and defines two edge surfaces. A second elongate member is also included which is disposed within the guidewire lumen and mates with the cross-sectional profile of the guidewire lumen of the first elongate member, thereby converting a guidewire lumen having a C-shaped design into one having an O-shaped design. The catheter may be used in rapid exchange catheter procedures requiring the use of small diameter guidewires which would otherwise slip out of the channel during use.

    摘要翻译： 一种用于胆汁手术过程中使用的导管系统，包括承载导丝管腔的第一细长构件和沿构件纵向延伸的通道，其提供对导丝管腔的通路并限定两个边缘表面。 还包括第二细长构件，其布置在导丝管腔内并且与第一细长构件的导丝管腔的横截面轮廓配合，从而将具有C形设计的导丝管腔转换为具有O形 设计。 导管可用于快速更换导管方法，需要使用小直径导丝，否则在使用过程中滑动通道。

    METHODS AND DEVICES FOR CELL CULTURING AND ORGAN ASSIST SYSTEMS
    4.
    发明申请
    METHODS AND DEVICES FOR CELL CULTURING AND ORGAN ASSIST SYSTEMS 审中-公开
    细胞培养和组织辅助系统的方法和装置

    公开(公告)号：WO0078920A9

    公开(公告)日：2002-09-06

    申请号：PCT/US0017138

    申请日：2000-06-21

    申请人： GEN HOSPITAL CORP ,  TONER MEHMET ,  YARMUSH MARTIN L ,  BALIS ULYSSES J ,  TILLES ARNO W

    发明人： TONER MEHMET ,  YARMUSH MARTIN L ,  BALIS ULYSSES J ,  TILLES ARNO W

    IPC分类号： A61F2/02 ,  A61M1/36 ,  C12M3/06 ,  C12N5/08 ,  C12M3/00

    CPC分类号： A61M1/3633 ,  A61F2/022 ,  A61M2210/1071 ,  C12M23/24 ,  C12M23/34 ,  C12M29/04 ,  C12M29/10 ,  C12M41/00

    摘要： The invention relates to new flow-through cell culturing devices (110) that include plates (112) arranged in parallel and spaced to control the flow patterns and velocity of liquid medium flowing between the plates (112). The devices can also include gas-permeable, liquid impermeable membranes arranged between the plates. The devices can be used to culture cells, such as hepatocytes, at high levels of mass transport of nutrients, oxygen, and waste products, yet low levels of shear stress for extended periods of time and with high levels of cell function, e.g., in organ assist systems. The invention also includes new culturing plates for use in the devices, and methods of manufacturing these plates.

    摘要翻译： 本发明涉及新的流通细胞培养装置（110），其包括平行布置并间隔开的板（112），以控制在板（112）之间流动的液体介质的流动模式和速度。 装置还可以包括布置在板之间的透气的液体不可渗透膜。 该装置可以用于培养细胞，如肝细胞，在营养物质，氧气和废物产品的高质量运输水平下，延长的时间段和高水平的细胞功能的低水平的剪切应力，例如， 器官辅助系统。 本发明还包括用于装置的新培养板以及制造这些板的方法。

    ORGAN SUPPORT SYSTEM
    5.
    发明申请
    ORGAN SUPPORT SYSTEM 审中-公开
    有机支持系统

    公开(公告)号：WO1994014496A1

    公开(公告)日：1994-07-07

    申请号：PCT/US1993012333

    申请日：1993-12-22

    申请人： HEPATIX, INC.

    发明人： HEPATIX, INC. ,  SUSSMAN, Norman, L. ,  KELLY, James, H. ,  LOBDELL, Donn, D.

    IPC分类号： A61M37/00

    CPC分类号： A61M1/3472 ,  A61M1/3406 ,  A61M1/3475 ,  A61M1/3489 ,  A61M2210/1071

    摘要： An organ support system and method adapted for use with a patient (200) and designed to modify the blood from the patient includes a control system (410), a venous line (2) coupled to an output of a patient, an arterial line (3) coupled to an input of the patient, and a cell line inserted into a hollow fiber cartridge (1) to form an organ assist device. Blood is passed through the organ assist device (1). A small flow is extracted from the extra-capillary space to check the integrity of the organ assist device. With this closed loop arrangement (110), a proper fluid balance can be maintained for the patient without requiring any dialysate, and leaks from the cell line to the patient can be immediately detected and prevented from reaching the patient.

    摘要翻译： 适于与患者（200）一起使用并被设计为修改来自患者的血液的器官支撑系统和方法包括控制系统（410），连接到患者的输出的静脉线（2），动脉线 3），其连接到患者的输入端，以及插入中空纤维筒（1）中以形成器官辅助装置的细胞系。 血液通过器官辅助装置（1）。 从毛细血管空间提取小流量以检查器官辅助装置的完整性。 利用该闭环装置（110），可以维持患者适当的流体平衡，而不需要任何透析液，并且可以立即检测并防止从细胞系向患者的泄漏到达患者。

    ADJUNCT MATERIALS FOR DELIVERY TO LIVER TISSUE
    6.
    发明申请
    ADJUNCT MATERIALS FOR DELIVERY TO LIVER TISSUE 审中-公开
    用于输送到肝组织的ADJUNCT材料

    公开(公告)号：WO2017040185A1

    公开(公告)日：2017-03-09

    申请号：PCT/US2016/048600

    申请日：2016-08-25

    申请人： ETHICON ENDO-SURGERY, LLC

    发明人： VENDELY, Michael J. ,  HARRIS, Jason L. ,  SHELTON, IV, Frederick E. ,  SCHEIB, Charles J.

    IPC分类号： A61B17/072

    CPC分类号： A61B17/072 ,  A61B17/07207 ,  A61B17/07292 ,  A61B17/115 ,  A61B17/1155 ,  A61B17/1219 ,  A61B2017/00004 ,  A61B2017/00889 ,  A61B2017/00893 ,  A61B2017/07271 ,  A61B2017/07285 ,  A61B2017/12004 ,  A61B2017/2927 ,  A61M37/00 ,  A61M2205/04 ,  A61M2210/1071

    摘要： Adjunct materials for delivery to liver tissue are provided. In general, the adjunct materials can be configured to be delivered to tissue by deployment of staples from a cartridge body of a surgical stapler. The adjunct material is configured to transition from an unexpanded configuration to an expanded configuration after delivery thereof to the liver tissue. The adjunct material can include an effective amount of one or more medicants, such as a hemostatic agent or a tissue healing agent, disposed within and releasable from the adjunct material for delivery to the liver tissue. The adjunct material can expand to apply pressure to liver tissue to facilitate sealing of one or more fractures in the stapled liver tissue. Methods of using a staple cartridge assembly or an end effector to apply such adjunct materials to liver tissue are also provided.

    摘要翻译： 提供了用于输送到肝组织的辅助材料。 通常，辅助材料可以构造成通过从外科缝合器的药筒主体部署缝钉而被递送到组织。 辅助材料被配置为在将其递送到肝组织之后从未膨胀构型转变为扩张构型。 辅助材料可以包括有效量的一种或多种药物，例如止血剂或组织愈合剂，其设置在辅助材料内并可从辅助材料中释放以递送至肝组织。 辅助材料可以膨胀以向肝组织施加压力，以便于缝合的肝组织中的一个或多个骨折的密封。 还提供了使用钉仓组件或端部执行器将这种辅助材料施用于肝组织的方法。

    A METHOD AND SYSTEM FOR TREATING HEPATITIS C
    7.
    发明申请
    A METHOD AND SYSTEM FOR TREATING HEPATITIS C 审中-公开
    一种治疗乙型肝炎的方法和系统

    公开(公告)号：WO2006068996A1

    公开(公告)日：2006-06-29

    申请号：PCT/US2005/045913

    申请日：2005-12-16

    申请人： CODMAN & SHURTLEFF, INC. ,  TIBOTEC, INC. ,  ZHAO, Ruilin ,  BAERT, Lieven, E., C. ,  SIMMEN, Kenneth, A.

    发明人： ZHAO, Ruilin ,  BAERT, Lieven, E., C. ,  SIMMEN, Kenneth, A.

    IPC分类号： A61M5/142

    CPC分类号： A61M5/14276 ,  A61M5/14232 ,  A61M5/152 ,  A61M2210/1071

    摘要： A method and system for treating Hepatitis C includes using an implantable pump and an outlet catheter. A proximal end of the outlet catheter is fluidly connected to an outlet port of the pump. A distal end of the outlet catheter is sized to deliver medication from the pump to a liver of living organism, preferably a human being. By delivering medication directly to the liver the effects of the antiviral therapeutics are enhanced, and the impact of Hepatitis C infection is reduced.

    摘要翻译： 用于治疗丙型肝炎的方法和系统包括使用可植入泵和出口导管。 出口导管的近端流体地连接到泵的出口。 出口导管的远端的尺寸被设计成将药物从泵输送到生物体的肝脏，优选人。 通过直接向肝脏输送药物，可以增强抗病毒药物的作用，降低丙型肝炎感染的影响。

    PERFUSION SYSTEM
    9.
    发明申请
    PERFUSION SYSTEM 审中-公开
    灌注系统

    公开(公告)号：WO01003755A1

    公开(公告)日：2001-01-18

    申请号：PCT/SE1999/001297

    申请日：1999-07-20

    IPC分类号： A61F2/958 ,  A61M1/36 ,  A61M29/02 ,  A61M25/10

    CPC分类号： A61M1/3621 ,  A61M1/3613 ,  A61M1/3615 ,  A61M25/1011 ,  A61M2025/1052 ,  A61M2025/1095 ,  A61M2210/1071

    摘要： A perfusion system for non-surgically perfusing an organ, particularly the liver, (101) in a patient, comprising bypass catheter means being percutaneously introducible into blood vessels of the organ and devised to bypass the blood flow past the organ; perfusion catheter means being percutaneously introducible into blood vessels and being devised to lead the flow of perfusion fluid through the organ; and occlusive seals (106, 108) devised to separate the bypass and perfusion circuits; a pump apparatus comprising a bypass pump (126), a perfusion pump (124) and means (134) for establishing a negative relative pressure at the perfusion outlet from the organ; and a perfusion control apparatus (128) devised to control the pump apparatus such that the outflow of fluid from the organ exceeds the inflow of fluid into the organ in the perfusion circuit due to a net volume contribution of blood from the systemic circulation entering the isolated organ.

    摘要翻译： 一种用于非手术灌注患者器官（特别是肝脏）（101）的灌注系统，包括旁路导管装置，其经皮可导入所述器官的血管，并设计为绕过所述血液通过所述器官; 灌注导管意味着经皮导入血管，并被设计成引导灌注流体流过器官; 和闭塞密封件（106,108），用于分离旁路和灌注回路; 泵装置，包括旁路泵（126），灌注泵（124）和用于在所述器官的灌注出口处建立负相对压力的装置（134） 以及设计用于控制泵装置的灌注控制装置（128），使得来自器官的流体的流出超过流体进入灌注回路中的器官，这是由于来自进入隔离物的全身循环的血液的净体积贡献 器官。

    DELIVERY OF A COMPOSITION TO THE LIVER BY UTILIZING THE PORTAL VEIN
    10.
    发明申请
    DELIVERY OF A COMPOSITION TO THE LIVER BY UTILIZING THE PORTAL VEIN 审中-公开
    通过利用门户网站向肝脏输送组合物

    公开(公告)号：WO0003652A9

    公开(公告)日：2000-07-27

    申请号：PCT/US9916069

    申请日：1999-07-16

    申请人： MANN MICHAEL J

    发明人： MANN MICHAEL J

    IPC分类号： A61M25/00 ,  A61F2/958 ,  A61B19/00

    CPC分类号： A61M25/10 ,  A61M25/007 ,  A61M2210/1071

    摘要： In general, the invention features methods and apparatuses for delivering a composition to the liver in a non-surgical, percutaneous approach by utilizing the portal vein. Also disclosed are methods allowing for the liver-specific delivery of a composition.

    摘要翻译： 通常，本发明的特征在于通过利用门静脉以非手术，经皮途径将组合物输送到肝脏的方法和装置。 还公开了允许组合物的肝特异性递送的方法。