Abstract:
A method and a system for quantitatively monitoring a chemical component dissolved in a liquid medium involve the creation, in a measurement chamber, of an interface zone between the liquid medium and an analytical reagent or reference solution; the measurement of the value of a measurement parameter in the interface zone, the parameter being a function of the concentration or amount of the chemical component to be monitored; and the derivation of the concentration or amount of the chemical component on the basis of the latter measured value and a baseline or reference value measured for the reagent or reference solution alone. Matrix effect(s) or ghosting error(s) are avoided. The method and the system can be used for on-line optimization and control of industrial chemical and/or biological processes, e.g. coupling reactions for the synthesis of azo compounds, monitoring of in vivo or in vitro biological systems as well as for conventional analytical purposes.
Abstract:
The present invention generally relates to continuous methods quantifying a target analyte concentration in a process solution. These methods are continuous automated titration methods that use titration chemistries to measure the target analyte concentration in the process solution. The method steps provide for efficient and robust automated titration methods for a variety of target analytes.
Abstract:
There is disclosed a device capable of continuously measuring the presence and concentration of an analyte or analytes and a method for using said device in a liquid and/or a gas phase reaction volume. The inventive device comprises a sensor probe, a reservoir, and a detection means. The inventive device delivers reagent to the sensor probe in a flow method to directly and continuously renew reagent, thereby allowing the continuous measurement of the presence and the concentration of an analyte or analytes.
Abstract:
In a method for measuring luminescence of a biological sample utilizing two different luminescence reagents, the sample is agitated to improve mixing with the second luminescence reagent, allowing for a shorter delay time between injection of the second reagent and measurement of the resulting luminescence activity. The improved mixing may also allow for a shorter measurement time, thereby improving throughput when assaying a large number of samples.
Abstract:
In an embodiment, an optical system comprises an optical cell having an interior fluid chamber defined by an interior surface of a housing, a process inlet disposed in the housing and in fluid communication with the interior fluid chamber, and a process outlet disposed in the housing and in fluid communication with the interior fluid chamber, wherein the process inlet and process outlet facilitate the flow of a fluid through the interior fluid chamber. A sampling outlet can be disposed in the housing and in fluid communication with the interior fluid chamber. A first bi-directional pump can be in fluid communication with the sampling outlet and a first storage vessel and can be configured to withdraw a first sample of the fluid via the sampling outlet and to cause the first sample to flow into the first storage vessel.
Abstract:
In an embodiment, an optical system comprises an optical cell having an interior fluid chamber defined by an interior surface of a housing, a process inlet disposed in the housing and in fluid communication with the interior fluid chamber, and a process outlet disposed in the housing and in fluid communication with the interior fluid chamber, wherein the process inlet and process outlet facilitate the flow of a fluid through the interior fluid chamber. A sampling outlet can be disposed in the housing and in fluid communication with the interior fluid chamber. A first bi-directional pump can be in fluid communication with the sampling outlet and a first storage vessel and can be configured to withdraw a first sample of the fluid via the sampling outlet and to cause the first sample to flow into the first storage vessel.
Abstract:
Detecting a definitive presence or absence of an analyte from a borderline test is shown and described. In one embodiment, a method of generating a definitive test result includes continuously incubating the assay concuiTently with continuously reading a diagnostic test on the assay. In particular examples, reading the diagnostic test on the assay includes performing a one minute diagnostic reading. Typically, when a borderline test result is detected, further development of the assay is performed. In most examples, detecting a definitive presence or absence test result deactivates the testing sequence.