公开(公告)号：WO2021248014A1

公开(公告)日：2021-12-09

申请号：PCT/US2021/035925

申请日：2021-06-04

Applicant: NEW YORK UNIVERSITY

Inventor： DVORAK, Dino ,  FENTON, Andre A.

IPC: A61B5/369 ,  A61B5/384 ,  A61B2505/07 ,  A61B5/165 ,  A61B5/291 ,  A61B5/6803 ,  A61B5/6843

Abstract: A system for precision psychiatry includes a wearable device including a cap and EEG electrodes attached thereto, the cap configured to be placed over a head of a user and including a plurality of first linear actuators configured to expand and contract to increase and decrease a size of the cap, respectively, the EEG electrodes connected to the cap via a plurality of second linear actuators configured to expand and contract to move the EEG electrode toward and away from, respectively, a scalp of the user, a processing device configured to be connected to the EEG electrodes of the wearable device to know the 3-D location of the EEG electrodes and to receive brain activity signals therefrom, the processing device generating a neurofeedback signal based on a detected aberrant brain activity, and a feedback device providing the neurofeedback signal to the user.

公开(公告)号：WO2021133440A1

公开(公告)日：2021-07-01

申请号：PCT/US2020/051060

申请日：2020-09-16

Applicant: FRESENIUS MEDICAL CARE HOLDINGS, INC.

Inventor： YUDS, David ,  PEESAPATI, Sameer

IPC: A61B5/145 ,  A61B5/0205 ,  A61B5/021 ,  A61B5/024 ,  A61K38/18 ,  A61B5/00 ,  G01L1/16 ,  A61M37/00 ,  A61M5/158 ,  A61B5/1455 ,  A61B2505/07 ,  A61B2560/0412 ,  A61B2560/0468 ,  A61B2562/0233 ,  A61B2562/0261 ,  A61B2562/164 ,  A61B5/0002 ,  A61B5/02416 ,  A61B5/14503 ,  A61B5/14535 ,  A61B5/4839 ,  A61B5/6824 ,  A61B5/6833 ,  A61K38/1816 ,  A61M2005/14208 ,  A61M2005/14252 ,  A61M2005/1726 ,  A61M2202/0433 ,  A61M2205/3327 ,  A61M2205/3553 ,  A61M2205/52 ,  A61M2230/04 ,  A61M5/1409 ,  A61M5/14248 ,  A61M5/1723 ,  G16H20/17 ,  G16H40/67 ,  G16H80/00

Abstract: Methods to treat anemia are provided whereby an erythropoietin stimulating agent (ESA) and an iron supplement are administered by a wearable device, based on patient parameters sensed by the wearable device. The method can involve monitoring patient parameters and dosing an ESA and an iron supplement in real-time, via the wearable device.

公开(公告)号：WO2022240774A1

公开(公告)日：2022-11-17

申请号：PCT/US2022/028389

申请日：2022-05-09

Applicant: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY

Inventor： CHOO, HyeRan

IPC: A61F5/56 ,  A61B5/00 ,  A61N1/05 ,  A61N1/36 ,  A61M21/02 ,  A61B2505/07 ,  A61B2560/0443 ,  A61B2562/0219 ,  A61B2562/0247 ,  A61B2562/0261 ,  A61B2562/0271 ,  A61B2562/029 ,  A61B5/087 ,  A61B5/1114 ,  A61B5/4818 ,  A61B5/4848 ,  A61B5/6819 ,  A61B5/682 ,  A61B5/6822 ,  A61B5/6823 ,  A61F5/566 ,  A61M16/049 ,  A61M16/161 ,  A61M2021/0016 ,  A61M2021/0022 ,  A61M2021/0027 ,  A61M2021/0072 ,  A61M2021/0077 ,  A61M2021/0083 ,  A61M21/00 ,  A61M2205/332 ,  A61M2205/3368 ,  A61M2205/3375 ,  A61M2205/3553 ,  A61M2205/3561 ,  A61M2205/3584 ,  A61M2205/3592 ,  A61M2205/505 ,  A61M2205/52 ,  A61M2205/582 ,  A61M2205/584 ,  A61M2205/8206 ,  A61M2205/8237 ,  A61M2207/00 ,  A61M2209/088 ,  A61M2210/0637 ,  A61M2210/0643 ,  A61M2230/40 ,  A61M2230/50 ,  A61M2230/60 ,  A61M2230/62 ,  A61M2230/63 ,  B33Y80/00 ,  G16H20/40

Abstract: Devices and methods for treating obstructive sleep apnea, habitual mouth breathing, and/or myofunctional therapy includes a body including an anterior end, a posterior end, and lateral portions shaped for introduction into a subject's oral cavity to position the anterior end adjacent front teeth of the subject and the posterior end adjacent the pharyngeal airway of the subject with or without the posterior end adjacent the pharyngeal airway. Sensors and/or stimulators may be provided, to generate electrical current, chemical release, vibration, and/or other stimulations, e.g., to activate neuromuscular contraction, stimulate salivation and subsequent swallowing movement, and/or induce partial wakefulness of the subject and/or to record data regarding the subject's tongue movements and/or position. Optionally, an extraoral sensor device may be provided for placement around the face, nose, check, abdomen, or neck, which may be paired with the intraoral device to detect the respiratory effort related airway obstruction.

公开(公告)号：WO2022155402A2

公开(公告)日：2022-07-21

申请号：PCT/US2022/012412

申请日：2022-01-14

Applicant: AIDPLEX INC.

IPC: H04W4/00 ,  H04W4/80 ,  H01M10/00 ,  G06F12/02 ,  G06F12/00 ,  A61F5/02 ,  G06F1/14 ,  G06F9/00 ,  A61B2505/07 ,  A61B2562/0247 ,  A61B5/0004 ,  A61B5/0022 ,  A61B5/0024 ,  A61B5/0053 ,  A61B5/0082 ,  A61B5/1036 ,  A61B5/4561 ,  A61B5/4566 ,  A61B5/6805 ,  A61B5/6812 ,  A61B5/6823 ,  A61B5/6831 ,  A61B5/6885 ,  A61B5/7275 ,  A61B5/742 ,  A61B5/7465 ,  A61F5/022 ,  A61F5/024

Abstract: A back brace is configured to be worn by a patient for treating spinal deformations. The back brace has at least one pressure sensor configured to be attached to the back brace at a point of pressure with the body of a patient, and at least one strap configured to be tightened for adjusting a pressure at the point of pressure. A control unit is configured to be attached to one of an outside of the back brace and inside a cavity formed in the back brace. The control unit is configured for (a) processing signals from the at least one pressure sensor, (b) communicating with at least one external computing apparatus, (c) informing and guiding in real time and incentivizing a patient to more efficiently wear the back brace by at least providing indications to the patient for tightening the at least one strap by comparing a pressure value provided by the at least one pressure sensor with at least one calibration value, and (d) enabling a doctor to more efficiently monitor, intervene, and manage the patient and treatment in real time.

公开(公告)号：WO2021253071A1

公开(公告)日：2021-12-23

申请号：PCT/AU2021/050569

申请日：2021-06-08

Applicant: UMPS HEALTH PTY LTD

Inventor： AYRE, Geoff ,  JAHNKE, Adam

IPC: G08B21/02 ,  G08B21/04 ,  G01R21/00 ,  G01S5/18 ,  A61B2503/08 ,  A61B2505/07 ,  A61B2562/0204 ,  A61B2562/0257 ,  A61B2562/0271 ,  A61B2562/029 ,  A61B5/0022 ,  A61B5/1113 ,  A61B5/1117 ,  A61B5/1118 ,  A61B5/6889 ,  A61B5/7267 ,  G01R22/10 ,  G01S11/14 ,  G05B2219/25011 ,  G08B21/0423 ,  G08B21/043 ,  G08B21/0461 ,  G08B21/0469 ,  G08B21/0476 ,  G08B21/22 ,  H03H21/003 ,  H04W4/023 ,  H04W4/029 ,  H04W4/38

Abstract: A device for tracking at least one user, the device comprising: a housing; at least one socket accessible via the housing, the socket having apertures to receive pins of an electrical plug for connecting at least one load to a primary power source; at least one energy sensor coupled to the housing configured to measure a change in electrical energy use by the load; at least one presence sensor coupled to the housing configured to determine when the user is proximate to the device; and a processor coupled to the housing configured to resolve from at least a portion of signals from the energy sensor and the presence sensor one or more components.

公开(公告)号：WO2021126352A1

公开(公告)日：2021-06-24

申请号：PCT/US2020/056103

申请日：2020-10-16

Applicant: LABORIE MEDICAL TECHNOLOGIES CORP.

Inventor： DACKO, Adrian, G. ,  COLE, David, Nathaniel ,  MAUNDER, Simon, B. ,  ZHANG, Hance

IPC: A61B5/20 ,  A61B5/00 ,  G01F3/00 ,  G01F1/50 ,  G01F23/14 ,  A61B2505/03 ,  A61B2505/07 ,  A61B2562/0247 ,  A61B2562/0252 ,  A61B5/202 ,  A61B5/208 ,  A61B5/7207 ,  A61B5/7221 ,  A61B5/725 ,  G01F23/0061 ,  G01F23/20 ,  G01F9/003 ,  G16H10/40 ,  G16H40/67

Abstract: Aspects of the disclosure are directed toward a method for providing uroflowmeter data. The method comprises receiving volume sample data representative of volume sample data from a uroflowmeter device, calculating the slope of the volume sample data, and performing additional actions if the calculated slope reaches a trigger threshold. If the calculated slope reaches a trigger threshold, the method may further determine if an artifact is present in the volume sample data. This may include comparing the morphology of the potential artifact to morphologies of known artifacts and comparing the value of the volume sample data before and after the potential artifact. If an artifact is determined to be present in the volume sample data and the volume sample data before the potential artifact is less than or equal to the volume sample data after the potential artifact, remove the portion of the volume sample data which represents the artifact.

公开(公告)号：WO2021122849A1

公开(公告)日：2021-06-24

申请号：PCT/EP2020/086579

申请日：2020-12-16

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： HILBIG, Rainer ,  BULUT, Murtaza ,  BOSMA, Robert, Willem ,  CHEN, Shuang ,  SHI, Jun

IPC: A61B5/00 ,  A61B5/0205 ,  A61B5/11 ,  G08B21/02 ,  A61B2503/04 ,  A61B2503/06 ,  A61B2505/07 ,  A61B2562/0257 ,  A61B2562/0271 ,  A61B5/02055 ,  A61B5/024 ,  A61B5/0816 ,  A61B5/1118 ,  A61B5/4812 ,  A61B5/681 ,  A61B5/6892 ,  A61B5/746 ,  F24F11/30 ,  G05B15/02 ,  G08B21/0208

Abstract: The invention provides a system for alerting a second subject (e.g. a parent) based on a wellbeing state of a first subject (e.g. a child) when the first subject is sleeping in the same room as the second subject. An arrangement of sensors is used for sensing data from the first subject and a processor is configured to determine the presence of the first subject from the sensing data. Based on the first subject being present, the processor is further configured to determine the state of the first subject based on the sensing data from the arrangement of sensors and then determine whether to alert the second subject based on the state of the first subject. An alarm is provided for alerting the second subject.

公开(公告)号：WO2021260192A1

公开(公告)日：2021-12-30

申请号：PCT/EP2021/067534

申请日：2021-06-25

Applicant: ECTOSENSE NV

Inventor： GEEURICKX, Wout ,  MASSIE, Frederik ,  VITS, Steven ,  VAN PEE, Bart

IPC: A61B5/02 ,  A61B5/026 ,  A61B5/0295 ,  A61B5/00 ,  A61B2505/07 ,  A61B5/02007 ,  A61B5/0261 ,  A61B5/4035 ,  A61B5/4815 ,  A61B5/4818 ,  A61B5/6826

Abstract: A computer-implemented method for assessing peripheral arterial tone (100), PAT, of an individual (1) monitored by optical plethysmography and for detecting therefrom occurrence of a sleep-related event, comprising: − obtaining: o an optical plethysmography signal (101) measured at an investigated volume (11); and o light intensities (102;103) acquired at two or more points in time (12;13) along said optical plethysmography signal (101); − determining changes in arterial blood volume (16) in said investigated volume (11) between said two or more points in time (12;13) by determining a logarithm (17) or a function approximation thereof (17) of a function of said light intensities (102;103), thereby assessing PAT (100) of said individual (1); and − determining a drop in said PAT (100) indicative for a vasoconstriction of arteries and arterioles in said investigated volume (11), thereby detecting occurrence of a sleep-related event.

公开(公告)号：WO2021222417A2

公开(公告)日：2021-11-04

申请号：PCT/US2021/029661

申请日：2021-04-28

Applicant: MEDTRONIC XOMED, INC.

Inventor： BERTRAND, Jeff William

IPC: A61M27/00 ,  A61B5/03 ,  A61B2505/07 ,  A61B2505/09 ,  A61B5/031 ,  A61B5/4836 ,  A61B5/6852 ,  A61B5/686 ,  A61M2202/0464 ,  A61M2205/3334 ,  A61M2205/52 ,  A61M2210/0693 ,  A61M2230/005 ,  A61M27/006

Abstract: Disclosed is a control system (60) for a shunt system (14) implantable in a subject (109). The control system may operate a selected portion of the shunt system, such as a flow control (30, 34). The control system may operate the shunt system with a closed feedback loop based upon selected sensor input to achieve selected or optimal outcomes.

公开(公告)号：WO2021150940A1

公开(公告)日：2021-07-29

申请号：PCT/US2021/014689

申请日：2021-01-22

Applicant: MEDTRONIC XOMED, INC.

Inventor： SCHEINER, Avram ,  HISSONG, James

IPC: A61N1/05 ,  A61B5/08 ,  A61B5/296 ,  A61B17/34 ,  A61N1/36 ,  A61N1/372 ,  A61B17/3403 ,  A61B17/3468 ,  A61B2017/00929 ,  A61B2505/07 ,  A61B5/395 ,  A61B5/397 ,  A61B5/4818 ,  A61B5/4848 ,  A61B5/682 ,  A61B5/686 ,  A61N1/0548 ,  A61N1/0551 ,  A61N1/0558 ,  A61N1/36003 ,  A61N1/3601 ,  A61N1/3611 ,  A61N1/37518

Abstract: A system for treatment of obstructive sleep apnea (OSA) is described. The system includes an introducer needle having an elongated body. The introducer needle is configured to create an opening in a tongue of a patient for implantation of a lead for treating OSA. One or more electrically conductive areas are located on the elongated body. A medical device is configured to deliver a stimulation signal via the introducer needle through the one or more electrically conductive areas to the tongue of the patient to stimulate one or more motor points of a protrusor muscle within the tongue of the patient.