公开(公告)号：WO2022238229A1

公开(公告)日：2022-11-17

申请号：PCT/EP2022/062141

申请日：2022-05-05

Applicant: KONINKLIJKE PHILIPS N.V. ,  PHILIPS IMAGE GUIDED THERAPY CORPORATION

Inventor： JENKINS, Rebecca Ann ,  WINKLER BROWN, Emily ,  SOTAK, Ryan Michael ,  NACHTOMY, Ehud ,  HELMSTRIJD, Ronald Christiaan

IPC: A61B8/08 ,  A61B8/12 ,  A61B8/00 ,  A61B6/00 ,  A61B6/4441 ,  A61B6/481 ,  A61B6/487 ,  A61B6/5247 ,  A61B8/0841 ,  A61B8/085 ,  A61B8/0883 ,  A61B8/0891 ,  A61B8/4245 ,  A61B8/4416 ,  A61B8/463 ,  A61B8/5207 ,  A61B8/5261

Abstract: A co-registration system includes a processor circuit that generates and displays a first co-registration reliability indicator based on the status of an x-ray imaging device and a second co-registration reliability indicator based on the speed of an intravascular catheter/guidewire. The processor circuit receives, from the x-ray imaging device, x-ray images of a blood vessel while the intravascular catheter/guidewire moves through the blood vessel. The processor circuit receives, from the catheter/guidewire, intravascular data representative of the blood vessel while the catheter/guidewire moves through the blood vessel. The processor circuit co-registers the intravascular data to an x-ray image received from the x-ray imaging device. The processor circuit also receives a signal representative of an inactive status of the x-ray imaging device during the movement of the catheter/guidewire. The processor circuit then displays the first reliability indicator representative of the x-ray fluoroscopy device status and may indicate that co-registration is not possible. The processor circuit also determines a speed of the catheter/guidewire and displays a second indicator representative of the speed of the catheter/guidewire being too fast for reliable co-registration.

公开(公告)号：WO2021263071A1

公开(公告)日：2021-12-30

申请号：PCT/US2021/039023

申请日：2021-06-25

Applicant: XENTER, INC.

Inventor： LINDER, Richard, J. ,  BEARSS, David, J.

IPC: A61B5/1455 ,  A61B5/00 ,  A61B5/05 ,  A61B5/145 ,  A61B8/00 ,  A61B8/0891 ,  A61B8/12 ,  A61B8/4494 ,  A61B8/463 ,  A61K47/6929 ,  A61N2007/0004 ,  A61N2007/0052 ,  A61N2007/0073 ,  A61N7/00 ,  B82Y5/00

Abstract: The present disclosure relates generally to nanoparticle-based imaging, binding, and/or therapy at a targeted anatomical location within a subject. In particular, certain embodiments relate to intraluminal devices and systems configured to apply nanoparticles to an imaging target and/or treatment target within an anatomical lumen and to communicate imaging and/or treatment data wirelessly to one or more external devices.

公开(公告)号：WO2021259714A1

公开(公告)日：2021-12-30

申请号：PCT/EP2021/066166

申请日：2021-06-16

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： SAVORD, Bernard, Joseph

IPC: G01S7/52 ,  G01S15/89 ,  A61B8/06 ,  A61B8/463 ,  A61B8/488 ,  G01S15/8913 ,  G01S15/8915 ,  G01S15/8979 ,  G01S7/5203 ,  G01S7/52066 ,  G01S7/5208

Abstract: An ultrasound system includes a transducer array configured to generate analog ultrasound signals. The system includes one or more analog-to-digital converters (ADCs) in communication with the transducer array. The ADCs is configured to convert the analog ultrasound signals to digital ultrasound signals. The system includes a processor circuit in communication with the ADCs. The processor circuit includes digital in-phase/quadrature (I/Q) mixers configured to generate digital continuous wave (CW) Doppler signals based on the digital ultrasound signals. The processor circuit is configured to process the digital CW Doppler signals, generate a graphical representation of a distribution of blood flow velocities over a plurality of cardiac cycles, and output the graphical representation to a display in communication with the processor circuit.

公开(公告)号：WO2022238276A1

公开(公告)日：2022-11-17

申请号：PCT/EP2022/062384

申请日：2022-05-07

Applicant: KONINKLIJKE PHILIPS N.V. ,  PHILIPS IMAGE GUIDED THERAPY CORPORATION

Inventor： NACHTOMY, Ehud ,  BROWN, Emily Winkler ,  ZARKH, Michael

IPC: A61B8/08 ,  A61B8/12 ,  A61B8/00 ,  A61B8/0841 ,  A61B8/0891 ,  A61B8/463 ,  A61B8/465 ,  A61B8/467 ,  A61B8/5261 ,  A61B8/5269

Abstract: A co-registration system includes a processor circuit that corrects the location of an indicator identifying a radiopaque portion of an intravascular catheter shown in an x-ray image and corrects the shape of a pathway defined by the movement of the radiopaque portion. The processor circuit receives, from the x-ray imaging device, x-ray images of a blood vessel while the intravascular catheter/guidewire moves through the blood vessel. The processor circuit receives, from the catheter, intravascular data representative of the blood vessel while the catheter moves through the blood vessel. The processor circuit co-registers the intravascular data to an x-ray image received from the x-ray imaging device. The processor circuit also displays the location indicator identifying the location of the radiopaque portion of the catheter in each x-ray image. In response to a user input, the processor circuit moves the location indicator to a corrected location. The processor circuit also modifies the shape of the pathway of the catheter in response to a user input. The processor circuit then completes the co-registration process again after either of these changes are made.

公开(公告)号：WO2022203713A2

公开(公告)日：2022-09-29

申请号：PCT/US2021/050973

申请日：2021-09-17

Applicant: BARD ACCESS SYSTEMS, INC.

Inventor： SOWARDS, Steffan ,  MISENER, Anthony, K. ,  MCLAUGHLIN, William, Robert

IPC: A61B8/00 ,  A61B5/06 ,  A61B2562/0219 ,  A61B2562/223 ,  A61B5/0077 ,  A61B5/067 ,  A61B5/743 ,  A61B5/748 ,  A61B5/749 ,  A61B8/4245 ,  A61B8/4254 ,  A61B8/4422 ,  A61B8/4433 ,  A61B8/4472 ,  A61B8/461 ,  A61B8/463 ,  A61B8/465 ,  A61B8/467 ,  A61B8/54 ,  A61B8/56

Abstract: An ultrasound system is disclosed that includes an ultrasound imaging device including a display screen, a processor and memory having stored thereon logic, and an ultrasound probe. The logic of the ultrasound imaging device, upon execution by the processor, can causes an alteration of content displayed on the display screen in accordance of with ultrasound probe movement-related data. The ultrasound imaging device can include a light source configured to provide incident light to the optical fiber cable, the optical fiber cable including a plurality of reflective gratings disposed along a length thereof. Each of the plurality of reflective gratings can be configured to reflect light with different specific spectral widths to provide distributed measurements in accordance with strain applied to the optical fiber cable. The ultrasound imaging device can obtain the ultrasound probe movement-related data through an optical fiber.

公开(公告)号：WO2021128765A1

公开(公告)日：2021-07-01

申请号：PCT/CN2020/096527

申请日：2020-06-17

Applicant: 深圳开立生物医疗科技股份有限公司

Inventor： 朱建武 ,  杨仲汉 ,  冯乃章

IPC: A61B8/06 ,  A61B8/08 ,  A61B8/461 ,  A61B8/463 ,  A61B8/481 ,  A61B8/488

Abstract: 一种超声成像方法、超声设备及存储介质，超声成像方法在扫查平面上的任意一个位置至少两次发射超声波组；发射的超声波组包括第一类型的超声波和第二类型的超声波，且第一类型的超声波与第二类型的超声波的幅度和相位中的至少一项不同。因此，超声波组的回波数据包括第一类型的超声波的回波数据（S1）和第二类型的超声波的回波数据（S2），并且第一类型的超声波的回波数据（S1）与第二类型的超声波的回波数据（S2）的幅度和相位中的至少一项不同。所以超声波组的回波数据至少包括用于得到血流超声图像的回波数据，以及用于得到造影超声图像的回波数据，从而可以实现利用一次扫查，达到血流超声图像以及造影超声图像双实时成像的目的。

公开(公告)号：WO2021122098A1

公开(公告)日：2021-06-24

申请号：PCT/EP2020/084853

申请日：2020-12-07

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： GERMOND ROUET, Laurence ,  CIOFOLO-VEIT, Cybèle ,  RAYNAUD, Caroline, Denise, Francoise ,  OLIVIER, Antoine

IPC: A61B8/08 ,  G06N3/04 ,  A61B8/085 ,  A61B8/0866 ,  A61B8/463 ,  A61B8/5223 ,  A61B8/523 ,  G06N20/10 ,  G06N3/0454 ,  G06N3/084 ,  G06N5/003 ,  G06N7/005

Abstract: The invention provides a method for determining a global confidence index for a 2D ultrasound image extracted from a 3D ultrasound volume, wherein the global confidence index indicates the suitability of the 2D ultrasound image for medical measurements. The method comprises obtaining a 3D ultrasound volume of a subject and extracting a set of at least one 2D ultrasound image from the 3D ultrasound volume. A set of geometrical indicators are then obtained with a first neural network, wherein each geometrical indicator indicates geometrical features of the anatomy of the subject. The set of 2D ultrasound images are then processed with a second neural network, wherein the output of the second neural network is a set of anatomical indicators and wherein the anatomical indicators indicate at least the presence of anatomical landmarks. A global confidence index is then determined for each one of the set of 2D ultrasound images based on the geometrical indicators and the anatomical indicators.

公开(公告)号：WO2022144177A2

公开(公告)日：2022-07-07

申请号：PCT/EP2021/086045

申请日：2021-12-16

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： BHARAT, Shyam ,  KRUECKER, Jochen ,  ERRICO, Claudia ,  ERKAMP, Ramon, Quido

IPC: A61B8/00 ,  A61B8/08 ,  A61B8/4245 ,  A61B8/4254 ,  A61B8/4416 ,  A61B8/4427 ,  A61B8/463 ,  A61B8/468 ,  A61B8/469 ,  A61B8/5207

Abstract: Systems and methods for ultrasound image acquisition, tracking and review are disclosed. The systems can include an ultrasound probe coupled with at least one tracking device configured to determine a position of the probe based on a combination of ultrasound image data and probe orientation data. The image data can be used to determine a physical reference point and superior-inferior probe coordinates within a patient being imaged, which can be supplemented with the probe orientation data to determine lateral coordinates of the probe. A graphical user interface can display imaging zones corresponding to a scan protocol, along with an imaging status of each zone based at least in part on the probe position. Ultrasound images acquired by the systems can be tagged with spatial indicators and severity indicators, after which the images can be stored for later retrieval and expert review.

公开(公告)号：WO2021257589A1

公开(公告)日：2021-12-23

申请号：PCT/US2021/037464

申请日：2021-06-15

Applicant: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH

Inventor： HUANG, Chengwu ,  CHEN, Shigao

IPC: A61B8/06 ,  A61B8/08 ,  G01S7/52 ,  A61B8/0891 ,  A61B8/463 ,  A61B8/467 ,  A61B8/469 ,  A61B8/481 ,  A61B8/5207 ,  A61B8/5269 ,  G01S15/8977 ,  G01S7/52039 ,  G06T3/4007 ,  G06T3/4053

Abstract: Systems and methods for high spatial and temporal resolution ultrasound imaging of microvessels in a subject are described. Ultrasound data are acquired from a region-of-interest in a subject who has been administered a microbubble contrast agent. The ultrasound data are acquired while the microbubbles are moving through, or otherwise present in, the region-of-interest. The region-of-interest may include, for instance, microvessels or other microvasculature in the subject. By imaging microbubbles, a cross-correlation map between each microbubble image and a point spread function of the system can be generated. Accumulation of power-based cross-correlation maps may then be used to generate a high-resolution high-contrast image of the microvasculature.

公开(公告)号：WO2021231230A1

公开(公告)日：2021-11-18

申请号：PCT/US2021/031415

申请日：2021-05-07

Applicant: ECHONOUS, INC.

Inventor： COOK, Matthew ,  LU, Allen

IPC: A61B8/08 ,  A61B8/00 ,  G16H30/40 ,  G16H50/20 ,  G06N20/00 ,  A61B8/14 ,  A61B8/463 ,  A61B8/469 ,  A61B8/5215 ,  G06K9/6267 ,  G06N3/0454 ,  G06N3/08 ,  G06T11/00 ,  G06T2207/10132 ,  G06T2207/20081 ,  G06T2207/20084 ,  G06T2207/30004 ,  G06T2210/12 ,  G06T7/0012 ,  G16H30/20 ,  G16H50/50

Abstract: A facility for processing a medical imaging image is described. The facility applies to the image a first machine learning model trained to recognize a view to which an image corresponds, and a second machine learning model trained to identify any of a set of anatomical features visualized in an image. The facility accesses a list of permitted anatomical features for images corresponding to the recognized view, and filters the identified anatomical features to exclude any not on the accessed list. The facility causes the accessed image to be displayed, overlaid with a visual indication of each of the filtered identified anatomical features.