公开(公告)号：WO2022204167A2

公开(公告)日：2022-09-29

申请号：PCT/US2022/021371

申请日：2022-03-22

Applicant: NEPHRIA BIO, INC.

Inventor： WELSFORD, Ian G. ,  KIM, Jesse

IPC: A61M1/14 ,  A61M1/16 ,  A61M1/28 ,  A61B5/145 ,  G01N13/04 ,  A61M1/155 ,  A61M1/156 ,  A61M1/1563 ,  A61M1/159 ,  A61M1/1621 ,  A61M1/1694 ,  A61M1/1696 ,  A61M1/281 ,  A61M1/3649 ,  A61M2205/3317 ,  A61M2205/3368 ,  A61M2205/502 ,  A61M2205/8206 ,  A61M2209/088

Abstract: Described here are systems, devices, and methods of renal replacement therapy. In some variations, a continuous ambulatory dialysis device may comprise a first fluid conduit configured to receive a fluid from a patient, a second fluid conduit configured to output the fluid to the patient, and an electroosmotic pump configured to pump and filter the fluid. The electroosmotic pump may be coupled between the first fluid conduit and the second fluid conduit. The electroosmotic pump may comprise a first electrode configured to adsorb urea in the fluid, a second electrode, and a porous substrate coupled therebetween.

公开(公告)号：WO2023009389A2

公开(公告)日：2023-02-02

申请号：PCT/US2022/037976

申请日：2022-07-22

Applicant: FRESENIUS MEDICAL CARE HOLDINGS, INC.

Inventor： YUDS, David ,  YI, Jun

IPC: A61M1/16 ,  A61J1/10 ,  A61J1/20 ,  A61L2/00 ,  A61M1/28 ,  C02F1/66 ,  C02F9/00 ,  A61J1/12 ,  A61J1/2024 ,  A61J1/2093 ,  A61L2/0047 ,  A61L2/10 ,  A61M1/1654 ,  A61M1/1668 ,  A61M1/1674 ,  A61M1/168 ,  A61M1/1696 ,  A61M1/287 ,  A61M1/67 ,  A61M1/69 ,  C02F1/32

Abstract: A method includes collecting used dialysis fluid in a container and combining the dialysis fluid with an acid to lower the pH value of the used dialysis fluid.

公开(公告)号：WO2022173523A2

公开(公告)日：2022-08-18

申请号：PCT/US2021/071641

申请日：2021-09-29

Applicant: UOP LLC

Inventor： LUPTON, Francis Stephen ,  LEWIS, Gregory J. ,  HODGES, James M. ,  JAKUBCZAK, Paulina ,  SYLEJMANI-REKALIU, Mimoza ,  SHEETS, William

IPC: B01D15/36 ,  B01J20/10 ,  B01J45/00 ,  A61K47/50 ,  A61P39/04 ,  A61K31/10 ,  A61K31/194 ,  A61K31/198 ,  A61K31/341 ,  A61K31/35 ,  A61K31/351 ,  A61K31/4184 ,  A61K31/423 ,  A61K31/44 ,  A61K33/24 ,  A61K38/063 ,  A61M1/1696 ,  A61M1/28 ,  A61M1/3679 ,  A61M1/3687 ,  B01D15/361 ,  B01D2325/42 ,  B01D69/02 ,  B01D69/08 ,  B01D69/147 ,  B01D69/148 ,  B01J39/14

Abstract: A process for removing Pb2+, Hg2+ and other heavy metal toxins from bodily fluids is disclosed. The process involves treating a patient with a small molecule heavy metal chelator to remove these toxins from bones and soft tissue cells into the blood or other bodily fluid. Then an ion exchange composition is used to ion exchange the heavy metal toxins from bodily fluids either within the body or by treatment outside the body such as by dialysis. The ion exchange compositions may be supported by porous networks of biocompatible polymers such as carbohydrates or proteins.

公开(公告)号：WO2022040376A2

公开(公告)日：2022-02-24

申请号：PCT/US2021/046603

申请日：2021-08-19

Applicant: VERTHERMIA ACQUISITION, INC.

Inventor： VERTREES, Roger ,  WINETZ, Jan

IPC: A61F7/00 ,  A61F7/12 ,  A61M1/36 ,  A61M1/14 ,  A61F2007/0054 ,  A61F2007/0086 ,  A61F2007/0093 ,  A61F2007/0096 ,  A61F2007/126 ,  A61F7/0085 ,  A61M1/16 ,  A61M1/1601 ,  A61M1/1696 ,  A61M1/3413 ,  A61M1/3609 ,  A61M1/3659 ,  A61M1/3666 ,  A61M1/3679 ,  A61M1/369 ,  A61M2205/05 ,  A61M2205/3334 ,  A61M2205/3368 ,  A61M2205/366 ,  A61M2230/202 ,  A61M2230/205 ,  A61M2230/50

Abstract: An improved system and methods for treatment of cancer and other diseases including complications from late-stage viral infections by inducing hyperthermia in a patient relying on withdrawing blood from the patient and returning the withdrawn blood to the patient to establish an extracorporeal flow circuit. Blood is heated by passing through the extracorporeal circuit at a controlled rate until a target body core temperature in is achieved. Usually, the blood will be subjected to a continuously re-circulating dialysis to balance electrolytes. Additionally, the blood will be subjected to a continuously recirculating regeneration through a carbon sorbent column where toxins and contaminants are removed. The blood temperature is maintained at the target blood temperature for a treatment period, and the blood is cooled after the treatment period has been completed. The method can also be effective in treating various ailments.

公开(公告)号：WO2021243200A1

公开(公告)日：2021-12-02

申请号：PCT/US2021/034844

申请日：2021-05-28

Applicant: GURA, Victor

Inventor： GURA, Victor

IPC: A61M1/26 ,  A61M1/16 ,  A61M1/1633 ,  A61M1/1649 ,  A61M1/1654 ,  A61M1/1696 ,  A61M1/267 ,  A61M1/34 ,  A61M1/3413 ,  A61M1/3626 ,  A61M2202/0413 ,  A61M2205/3324 ,  A61M2205/3334 ,  A61M2205/502 ,  A61M2205/75 ,  A61M2205/8206 ,  A61M2209/088

Abstract: The present disclosure includes systems and methods for hemodialysis, such as including a first dialysis module and an auxiliary module detachably connectable to the first dialysis module. The first dialysis module can include a dialyzer, a blood circuit, a dialysate circuit, and a sorbent. The auxiliary module can include an ultrafiltrate collector operably couplable to the dialysate circuit for removing excess fluid therefrom.