-
公开(公告)号:WO2022174497A1
公开(公告)日:2022-08-25
申请号:PCT/CN2021/083762
申请日:2021-03-30
申请人: 清华大学
摘要: 本申请提供一种人工组织器官的封装装置及其制备方法和应用,所述封装装置设在人工组织器官的外围,所述封装装置对所述人工组织器官的包封率为20%~100%,所述封装装置具有100Pa~1GPa的硬度。该封装装置在体外阶段,对人工组织器官提供保护、支撑、按需组合、装配和功能维持等作用,可实现安全精准和大规模的人工组织器官培养与运输、构建、培养与换液等操作,进而实现生物发育研究、高通量药物检测、大气/环境/水体检测等应用;体内阶段,对人工组织器官提供移植手术的移植体转移、定位和固定、缝合、结构保护、营养代谢维持等作用,进而促进移植组织器官的体内存活、血管化、组织形成和重建等作用。
-
公开(公告)号:WO2022125537A2
公开(公告)日:2022-06-16
申请号:PCT/US2021/062189
申请日:2021-12-07
发明人: SODE, Koji , DICK, Jeffrey , WALKER, Nicole , PROBST, David , LEE, Inyoung , TAKAMATSU, Shouhei
IPC分类号: C12N11/08 , C12N11/14 , C12N9/80 , C12Q1/001 , C12Q1/005 , C12Q1/006 , C12Q1/26 , G01N33/5438
摘要: Devices and methods are disclosed for measuring a target substance concentration in a sample utilizing a biosensor.
-
公开(公告)号:WO2022068093A1
公开(公告)日:2022-04-07
申请号:PCT/CN2020/137649
申请日:2020-12-18
申请人: 中国科学院天津工业生物技术研究所
摘要: 涉及可降解复合材料在吸油中的用途,所述可降解复合材料包括真菌菌丝形成的三维立体网状结构和被所述三维立体网状结构固定的至少一个木质纤维素碎屑。所述可降解复合材料具有较好的吸油性能,在石油泄漏、水上油污清除、含油废水的处理等方面有着良好的应用潜力。进一步可以解决秸秆、木屑等农业剩余物和林业剩余物处理的难题,增加这些剩余物的附加值,减少环境污染,有助于经济、生态环境和社会的协调发展。
-
公开(公告)号:WO2022065328A1
公开(公告)日:2022-03-31
申请号:PCT/JP2021/034677
申请日:2021-09-22
申请人: 株式会社JBM , メビオール株式会社 , 有限会社ジーエヌコーポレーション
发明人: 加藤 正二郎 , 吉岡 浩 , アブラハム サミュエル ジェイケー
摘要: 本発明の課題は、細胞集団の組織再生能を高める方法、当該方法を含む細胞集団の製造方法、当該方法によって製造された細胞集団を提供することにある。本発明は、(1)細胞集団の組織再生能を高める方法であって、細胞集団をゲル状態の熱可逆性ポリマー溶液中でインキュベートするステップを含む、前記方法、(2)該方法を含む、細胞集団の製造方法、(3)該製造方法によって製造された細胞集団などに関する。
-
公开(公告)号:WO2022031314A2
公开(公告)日:2022-02-10
申请号:PCT/US2021/010032
申请日:2021-08-03
申请人: ONCOVIR, INC.
IPC分类号: C12N11/087 , C12N11/02 , C12N11/08 , C12N11/06 , C12P19/30 , C12P19/34 , C12Q1/6806
摘要: A scalable process for production of polyribonucleotides of controlled molecular weight range through variation of processing time and input concentrations. Key elements include a method for immobilization of polynucleotide phosphorylase which has been covalently attached to an amino-functionalized solid support via a glutaraldehyde linkage; a method of repeatedly reacting inosine diphosphate or cytidine diphosphate monomer s with immobilized polynucleotide phosphorylase to produce polyribonucleotide chains; control of the chain length of Poly(I) and Poly(C) by varying cofactor concentration and the length of reaction time; a method for controlled and efficient large-scale manufacture of a specific, determined range of molecular weight poly I and poly C homopolymer chains.
-
公开(公告)号:WO2021211976A2
公开(公告)日:2021-10-21
申请号:PCT/US2021/027693
申请日:2021-04-16
摘要: A polyacrylamide-based copolymer reduces or prevents aggregation of biologic molecules including proteins, peptides, and nucleic acids, and lipid-based vehicles such as liposomes, lipid nanoparticles, polymerosomes, and micelles, in aqueous formulations at hydrophobic interfaces, thereby increasing the thermal stability of the molecules in the formulation. Methods and compositions comprising the copolymer and a protein or the copolymer and insulin can be used for treating conditions including diabetes.
-
公开(公告)号:WO2020174932A1
公开(公告)日:2020-09-03
申请号:PCT/JP2020/001755
申请日:2020-01-20
申请人: 浜松ホトニクス株式会社
IPC分类号: C12M1/42 , C12N5/00 , C12N11/00 , C12N11/08 , C12N11/089
摘要: 本発明の一形態に係る細胞接着用組成物は、両親媒性化合物と、DNA及び親水性分子のコンジュゲートと、を含み、両親媒性化合物は、細胞膜に非共有結合可能な疎水性基と、親水性基と、を有し、コンジュゲートの親水性分子の重量平均分子量は、両親媒性化合物の親水性基が由来する親水性分子の重量平均分子量よりも大きい。かかる細胞接着用組成物によれば、任意の波長を有する光を用いて、任意のタイミングで基材に細胞接着能を付与することができる。
-
公开(公告)号:WO2020021549A1
公开(公告)日:2020-01-30
申请号:PCT/IL2019/050838
申请日:2019-07-24
申请人: LAVIE BIO LTD.
摘要: A dehydrated composition containing a particle encapsulating one or more microorganisms is provided. The composition is useful for controlling the release of the microorganisms following rehydration and propagation within the particle.
-
9.
公开(公告)号:WO2019222048A1
公开(公告)日:2019-11-21
申请号:PCT/US2019/031733
申请日:2019-05-10
IPC分类号: C08F12/36 , C08F212/08 , C08F8/08 , C08F2/20 , C08J9/20 , C08L25/02 , C08F6/24 , C08F8/12 , C08F8/06 , C08F112/36 , C12N11/08 , C12N9/04 , B01J20/26
摘要: The invention involves functionalizing polymeric beads, such as DVB beads, to add an epoxide or aldehyde group. The resulting beads are useful In various applications.
-
公开(公告)号:WO2018195279A1
公开(公告)日:2018-10-25
申请号:PCT/US2018/028306
申请日:2018-04-19
申请人: PINT AT HOME, LLC
发明人: KOHLER, James , RISSI, Michael
摘要: Embodiments described herein generally relate to systems and methods for processing non-fermented liquids. In some embodiments, non-fermented liquids may be processed into fermentable liquids in relatively short time (e.g., less than or equal to 30 minutes). In certain embodiments, the non-fermented liquids may be processed in relatively small batches (e.g., having a volume of less than or equal to 2 liters). The systems and methods described herein may be useful for producing fermented (e.g., alcoholic) beverages by a consumer. Advantageously, the systems and methods may be for use by a consumer where, upon introduction of a non-fermented liquid into the system, a fermented beverage is produced (e.g., in relatively small batches and/or in relative short times) as compared to traditional fermentation systems and methods (e.g., requiring relatively long fermentation times and/or relatively large batches). In certain embodiments, the systems and methods produce fermented beverages in a substantially continuous manner (e.g., as compared to traditional fermentation systems which utilize batch and/or semi-batch processes). Such systems may be useful for, for example, on-demand brewing of alcoholic beverages.
-
-
-
-
-
-
-
-
-