公开(公告)号：WO2023273336A1

公开(公告)日：2023-01-05

申请号：PCT/CN2022/074409

申请日：2022-01-27

Applicant: 之江实验室

Inventor： 朱闻韬 ,  杨宝 ,  吴元锋

IPC: G06T11/00 ,  G06N3/045 ,  G06N3/08 ,  G06T11/006 ,  G06T11/008 ,  G06T2207/10081 ,  G06T2207/10104 ,  G06T2207/20056 ,  G06T2207/20081 ,  G06T2207/20084 ,  G06T2211/424 ,  G06T5/002

Abstract: 本发明公开了一种基于多任务学习约束的PET图像感兴趣区域增强重建方法，该方法先获取PET原始数据在图像域的反投影图像，设计重建主任务为利用三维深度卷积神经网络建立反投影图像与PET重建图像之间的映射。设计新增辅助任务一从反投影图像中预测与PET重建图像具有相同解剖结构的电子计算机断层扫描(CT)图像，从而利用高分辨率CT图像的局部平滑信息降低PET重建图像中的噪声。设计新增任务二实现区分反投影图像中的感兴趣区域与背景区域，在重建过程中对感兴趣区域进行增强重建，降低感兴趣区域由平滑导致的定量误差，提高PET重建精度。

公开(公告)号：WO2021191151A1

公开(公告)日：2021-09-30

申请号：PCT/EP2021/057275

申请日：2021-03-22

Applicant: AARHUS UNIVERSITET

Inventor： HANSEN, Thomas, Mejer

IPC: G06T11/00 ,  G06T11/006

Abstract: A device and a method for image reconstruction for medical imaging is provided. The method comprises obtaining a lookup table of pre-computed sets of data, obtaining a PET image, dividing the PET image into subset-images of one, or more, pixels. For each subset-image of pixels in the PET image, an extended rejection sampler is used to select model-images from the lookup table, determining and outputting a representation image based on the posterior distribution.

公开(公告)号：WO2021140309A1

公开(公告)日：2021-07-15

申请号：PCT/GB2020/053170

申请日：2020-12-10

Applicant: ADAPTIX LTD

Inventor： TRAVISH, Gil ,  WELLS, Steve ,  MITCHELL, Ian ,  HOLDEN, Martin

IPC: G06T11/00 ,  A61B6/032 ,  G01N23/046 ,  G06T11/003 ,  G06T11/006 ,  G06T2211/424

Abstract: The present invention seeks to reduce the burden of producing high-resolution tomograms by using an initial scan on a predetermined grid 10 to obtain a minimal set of images, and then regions of interest 20 are identified for further scanning. The further scanning locations 40 are determined by image entropy or gradient found in the previous iteration; such regions are indicative of edges, cracks or complex structure within the region. After each iteration, the level of information (e.g. image entropy or gradient) will decrease relative to the pixel/voxel size. In this way, a more efficient way to scan is achieved.

公开(公告)号：WO2022212871A1

公开(公告)日：2022-10-06

申请号：PCT/US2022/023098

申请日：2022-04-01

Applicant: AIXSCAN INC.

Inventor： MAOLINBAY, Manat ,  KU, Chwen-yuan ,  YANG, Linbo ,  LIU, Jianqiang

IPC: A61B6/08 ,  A61B6/02 ,  A61B5/00 ,  A61B6/00 ,  G01N23/04 ,  A61B6/025 ,  A61B6/032 ,  A61B6/035 ,  A61B6/0407 ,  A61B6/06 ,  A61B6/4007 ,  A61B6/4014 ,  A61B6/4021 ,  A61B6/405 ,  A61B6/4208 ,  A61B6/4275 ,  A61B6/4283 ,  A61B6/4405 ,  A61B6/4441 ,  A61B6/4452 ,  A61B6/4476 ,  A61B6/4482 ,  A61B6/467 ,  A61B6/482 ,  A61B6/502 ,  A61B6/54 ,  A61B6/541 ,  A61B6/542 ,  A61B6/56 ,  A61B6/583 ,  G01N2223/401 ,  G01N23/044 ,  G01N23/083 ,  G01N23/18 ,  G06T11/003 ,  G06T11/006 ,  G06T17/00 ,  G06T2200/24 ,  G06T2207/10076 ,  G06T2207/10081 ,  G06T2207/20081 ,  G06T2207/20084 ,  G06T2207/30064 ,  G06T2207/30096 ,  G06T2207/30168 ,  G06T2210/41 ,  G06T7/0012 ,  G06T7/0016 ,  G06T7/11 ,  G06V10/25 ,  G06V10/62 ,  G06V2201/032 ,  G16H10/60 ,  G16H30/20 ,  G16H50/20

Abstract: A transport system with curved track pair is constructed for multiple pulsed X-ray source-in-motion to perform fast digital tomosynthesis imaging. It includes a curved rigid track pair with predetermined curvature, a primary motor stage car loaded with X-ray sources and wheels loaded with tension or compression springs. The car is driven by primary motor mounted at base frame and an engaged gear mounted at the car. The car can carry heavy loads, travel with high precision and high repeatability at all installation orientations while motion vibration is minimal. It is also scalable to have a larger radius. Track angle span usually can be from about ten degrees to about 170 degrees. During imaging acquisition, X-ray sources can sweep precisely from one location to another. The car has enough clearance to move in its path without rubbing wheels on tracks.

公开(公告)号：WO2022211887A1

公开(公告)日：2022-10-06

申请号：PCT/US2022/013800

申请日：2022-01-26

Applicant: AIXSCAN INC.

Inventor： MAOLINBAY, Manat ,  KU, Chwen-Yuan ,  YANG, Linbo ,  LIU, Jianqiang

IPC: A61B6/02 ,  A61B6/025 ,  A61B6/032 ,  A61B6/035 ,  A61B6/0407 ,  A61B6/06 ,  A61B6/08 ,  A61B6/4007 ,  A61B6/4014 ,  A61B6/4021 ,  A61B6/405 ,  A61B6/4208 ,  A61B6/4275 ,  A61B6/4283 ,  A61B6/4405 ,  A61B6/4441 ,  A61B6/4452 ,  A61B6/4476 ,  A61B6/4482 ,  A61B6/467 ,  A61B6/482 ,  A61B6/502 ,  A61B6/54 ,  A61B6/541 ,  A61B6/542 ,  A61B6/56 ,  A61B6/583 ,  G01N2223/401 ,  G01N23/044 ,  G01N23/083 ,  G01N23/18 ,  G06T11/003 ,  G06T11/006 ,  G06T17/00 ,  G06T2200/24 ,  G06T2207/10076 ,  G06T2207/10081 ,  G06T2207/20081 ,  G06T2207/20084 ,  G06T2207/30064 ,  G06T2207/30096 ,  G06T2207/30168 ,  G06T2210/41 ,  G06T7/0012 ,  G06T7/0016 ,  G06T7/11 ,  G06V10/25 ,  G06V10/62 ,  G06V2201/032 ,  G16H10/60 ,  G16H30/20 ,  G16H50/20

Abstract: An X-ray imaging system using multiple pulsed X-ray sources in motion to perform high efficient and ultrafast 3D radiography using an X-ray flexible curved panel detector is presented. There are multiple pulsed X-ray sources mounted on a structure in motion to form an array of sources. The sources move simultaneously relative to an object on a predefined arc track at a constant speed as a group. Each individual X-ray source can move around its static position at a small distance. When an individual source has a speed equal to group speed, but with opposite moving direction, the individual source and detector are activated. This allows source to stay relatively standstill during activation. The operation results in reduced source travel distance for each individual source. 3D radiography image data can be acquired with much wider sweep angle in much shorter time, and image analysis can also be done in real-time.

公开(公告)号：WO2022211886A1

公开(公告)日：2022-10-06

申请号：PCT/US2022/013797

申请日：2022-02-11

Applicant: AIXSCAN INC.

Inventor： MAOLINBAY, Manat ,  KU, Chwen-Yuan ,  YANG, Linbo ,  LIU, Jianqiang

IPC: A61B6/00 ,  A61N5/10 ,  H05G1/10 ,  A61B6/025 ,  A61B6/032 ,  A61B6/035 ,  A61B6/0407 ,  A61B6/06 ,  A61B6/08 ,  A61B6/4007 ,  A61B6/4014 ,  A61B6/4021 ,  A61B6/405 ,  A61B6/4208 ,  A61B6/4275 ,  A61B6/4283 ,  A61B6/4405 ,  A61B6/4441 ,  A61B6/4452 ,  A61B6/4476 ,  A61B6/4482 ,  A61B6/467 ,  A61B6/482 ,  A61B6/502 ,  A61B6/54 ,  A61B6/541 ,  A61B6/542 ,  A61B6/56 ,  A61B6/583 ,  G01N2223/401 ,  G01N23/044 ,  G01N23/083 ,  G01N23/18 ,  G06T11/003 ,  G06T11/006 ,  G06T17/00 ,  G06T2200/24 ,  G06T2207/10076 ,  G06T2207/10081 ,  G06T2207/20081 ,  G06T2207/20084 ,  G06T2207/30064 ,  G06T2207/30096 ,  G06T2207/30168 ,  G06T2210/41 ,  G06T7/0012 ,  G06T7/0016 ,  G06T7/11 ,  G06V10/25 ,  G06V10/62 ,  G06V2201/032 ,  G16H10/60 ,  G16H30/20 ,  G16H50/20

Abstract: An X-ray imaging system using multiple pulsed X-ray sources in motion to perform high efficient and ultrafast 3D radiography using an X-ray flexible curved panel detector is presented. There are multiple pulsed X-ray sources mounted on a structure in motion to form an array of sources. The sources move simultaneously relative to an object on a predefined arc track at a constant speed as a group. Each individual X-ray source can move around its static position at a small distance. When an individual source has a speed equal to group speed, but with opposite moving direction, the individual source and detector are activated. This allows source to stay relatively standstill during activation. The operation results in reduced source travel distance for each individual source. 3D radiography image data can be acquired with much wider sweep angle in much shorter time, and image analysis can also be done in real-time.

公开(公告)号：WO2021198084A1

公开(公告)日：2021-10-07

申请号：PCT/EP2021/057965

申请日：2021-03-26

Applicant: VARIAN MEDICAL SYSTEMS INTERNATIONAL AG

Inventor： LEHMANN, Mathias ,  ANSORGE, Reto ,  WASER, Manuel ,  MORF, Daniel

IPC: A61B6/00 ,  A61N5/10 ,  G01N23/046 ,  H04N5/341 ,  A61B6/03 ,  A61B6/032 ,  A61B6/40 ,  A61B6/4085 ,  A61B6/42 ,  A61B6/4233 ,  A61B6/4266 ,  A61B6/4283 ,  A61B6/5205 ,  A61B6/583 ,  A61N2005/1061 ,  A61N5/1049 ,  A61N5/1077 ,  G01N2223/401 ,  G06T11/005 ,  G06T11/006 ,  G06T2211/424

Abstract: A cone-beam computed tomography (CBCT) method uses a continuous beam and an area detector to carry out fast acquisition of projection data. The acquired projection data are then reconstructed to generate tomographic images. In acquisition of the projection data, a radiation source (102) continuously irradiates a subject (112) with a cone beam (116) of radiation from a plurality of angles and an area detector (104) continuously reads out data. A CBCT system including a source operable to produce a cone beam of radiation and an area detector movable in synchrony with the source to rapidly acquire projection data for CBCT construction is also disclosed.

公开(公告)号：WO2022212010A2

公开(公告)日：2022-10-06

申请号：PCT/US2022/020130

申请日：2022-03-14

Applicant: AIXSCAN INC.

Inventor： MAOLINBAY, Manat ,  KU, Chwen-Yuan ,  YANG, Linbo ,  LIU, Jianqiang

IPC: A61B6/02 ,  A61B6/03 ,  G16H50/20 ,  A61B6/025 ,  A61B6/032 ,  A61B6/035 ,  A61B6/0407 ,  A61B6/06 ,  A61B6/08 ,  A61B6/4007 ,  A61B6/4014 ,  A61B6/4021 ,  A61B6/405 ,  A61B6/4208 ,  A61B6/4275 ,  A61B6/4283 ,  A61B6/4405 ,  A61B6/4441 ,  A61B6/4452 ,  A61B6/4476 ,  A61B6/4482 ,  A61B6/467 ,  A61B6/482 ,  A61B6/502 ,  A61B6/54 ,  A61B6/541 ,  A61B6/542 ,  A61B6/56 ,  A61B6/583 ,  G01N2223/401 ,  G01N23/044 ,  G01N23/083 ,  G01N23/18 ,  G06T11/003 ,  G06T11/006 ,  G06T17/00 ,  G06T2200/24 ,  G06T2207/10076 ,  G06T2207/10081 ,  G06T2207/20081 ,  G06T2207/20084 ,  G06T2207/30064 ,  G06T2207/30096 ,  G06T2207/30168 ,  G06T2210/41 ,  G06T7/0012 ,  G06T7/0016 ,  G06T7/11 ,  G06V10/25 ,  G06V10/62 ,  G06V2201/032 ,  G16H10/60 ,  G16H30/20

Abstract: Disclosed are image recognition Artificial Intelligence (AI) training methods for multiple pulsed X-ray source-in-motion tomosynthesis imaging system. Image recognition AI training can be performed three ways: first, using existing acquired chest CT data set with known nodules to generate synthenic tomosynthesis Images, no X-ray radiation applied; second, taking X-ray raw images with anthropomorphic chest phantoms with simulated lung nodules, applying X-ray beam on phantom only; third, acquiring X-ray images using multiple pulsed source-in-motion tomosynthesis images from real patients with real known nodules and without nodules. An X-ray image recognition training network that is configured to receive X-ray training images, automatically determine whether the received images indicate a nodule or lesion condition. After training, image knowledge is updated and stored at knowledge database.

公开(公告)号：WO2022211955A1

公开(公告)日：2022-10-06

申请号：PCT/US2022/018421

申请日：2022-03-02

Applicant: AIXSCAN INC.

Inventor： MAOLINBAY, Manat ,  KU, Chwen-Yuan ,  YANG, Linbo ,  LIU, Jianqiang

IPC: A61B6/00 ,  A61B5/00 ,  G06K9/00 ,  G06T7/00 ,  A61B6/025 ,  A61B6/032 ,  A61B6/035 ,  A61B6/0407 ,  A61B6/06 ,  A61B6/08 ,  A61B6/4007 ,  A61B6/4014 ,  A61B6/4021 ,  A61B6/405 ,  A61B6/4208 ,  A61B6/4275 ,  A61B6/4283 ,  A61B6/4405 ,  A61B6/4441 ,  A61B6/4452 ,  A61B6/4476 ,  A61B6/4482 ,  A61B6/467 ,  A61B6/482 ,  A61B6/502 ,  A61B6/54 ,  A61B6/541 ,  A61B6/542 ,  A61B6/56 ,  A61B6/583 ,  G01N2223/401 ,  G01N23/044 ,  G01N23/083 ,  G01N23/18 ,  G06T11/003 ,  G06T11/006 ,  G06T17/00 ,  G06T2200/24 ,  G06T2207/10076 ,  G06T2207/10081 ,  G06T2207/20081 ,  G06T2207/20084 ,  G06T2207/30064 ,  G06T2207/30096 ,  G06T2207/30168 ,  G06T2210/41 ,  G06T7/0012 ,  G06T7/0016 ,  G06T7/11 ,  G06V10/25 ,  G06V10/62 ,  G06V2201/032 ,  G16H10/60 ,  G16H30/20 ,  G16H50/20

Abstract: The presented are X-ray diagnosis method and system using multiple pulsed X-ray source-in-motion tomosynthesis imaging technology. While taking X-ray instrument image data, artificial intelligence (AI) analyzes patient responses, compares current condition with the patient history and other patient information that may become part of a patient. It reports lesions location changes, sets severity threshold and warning status, generate treatment information. It also recommend to a X-ray region of interest (ROI) scan, a complete X-ray CT scan or other health care professionals and specialists.

公开(公告)号：WO2022211954A1

公开(公告)日：2022-10-06

申请号：PCT/US2022/018420

申请日：2022-03-02

Applicant: AIXSCAN INC.

Inventor： MAOLINBAY, Manat ,  KU, Chwen-Yuan ,  YANG, Linbo ,  LIU, Jianqiang

IPC: A61B6/03 ,  A61B6/025 ,  A61B6/032 ,  A61B6/035 ,  A61B6/0407 ,  A61B6/06 ,  A61B6/08 ,  A61B6/4007 ,  A61B6/4014 ,  A61B6/4021 ,  A61B6/405 ,  A61B6/4208 ,  A61B6/4275 ,  A61B6/4283 ,  A61B6/4405 ,  A61B6/4441 ,  A61B6/4452 ,  A61B6/4476 ,  A61B6/4482 ,  A61B6/467 ,  A61B6/482 ,  A61B6/502 ,  A61B6/54 ,  A61B6/541 ,  A61B6/542 ,  A61B6/56 ,  A61B6/583 ,  G01N2223/401 ,  G01N23/044 ,  G01N23/083 ,  G01N23/18 ,  G06T11/003 ,  G06T11/006 ,  G06T17/00 ,  G06T2200/24 ,  G06T2207/10076 ,  G06T2207/10081 ,  G06T2207/20081 ,  G06T2207/20084 ,  G06T2207/30064 ,  G06T2207/30096 ,  G06T2207/30168 ,  G06T2210/41 ,  G06T7/0012 ,  G06T7/0016 ,  G06T7/11 ,  G06V10/25 ,  G06V10/62 ,  G06V2201/032 ,  G16H10/60 ,  G16H30/20 ,  G16H50/20

Abstract: System and method are disclosed for imaging acquisition from sparse partial scans of distributed wide angle. During real time image reconstruction, artificial intelligence (AI) determines if there is enough information to perform diagnostics based on initial scans. If there is enough information from the fractional scans, then data acquisition stops; if more information is needed, then system performs another round of wide-angle sparse scans in a new location progressively until a result is satisfactory. The system reduces X-ray dose on a patient and performs quicker X-ray scan at multiple pulsed source-in-motion tomosynthesis imaging system. The method and system also significantly reduce the amount of time required to display high quality three-dimensional tomosynthesis images.