利索-全球专利检索

  1. 登录
  2. 注册
发明公开
CN1675154A 抑制巨噬细胞移动抑制因子(MIF)的细胞因子或生物活性的萘衍生物 无效 - 撤回

抑制巨噬细胞移动抑制因子(MIF)的细胞因子或生物活性的萘衍生物
摘要：
本发明提供式(II)化合物及抑制巨噬细胞移动抑制因子(MIF)细胞因子或生物活性的方法，所述方法包括用式(I)化合物与MIF接触，其中Y、R1－R8和R101－R108同本说明书中定义。本发明也涉及治疗与MIF细胞因子或生物活性有关的疾病或病症的方法，所述方法包括独给予或作为联合疗法的部分给予式(I)化合物。
摘要（英）：

Where Y, R1-R8 and R101-R108 are as defined in the specification. Compounds of formula (II) and methods of inhibiting the cytokine or biological activity of Macrophage Migrating Inhibitory Factor (MIF) comprising contacting MIF with a compound of formula (I) are provided. The invention also relates to methods of treating diseases or conditions where MIF cytokine or biological activity is implicated comprising administration of compounds of formula (1), either alone or as part of a combination therapy.

0/0