发明公开
EP1311673A2 COMPOSITIONS AND METHODS FOR THE THERAPY AND DIAGNOSIS OF PROSTATE CANCER
审中-公开
UN组合工艺可用于治疗和诊断前列腺癌
- 专利标题: COMPOSITIONS AND METHODS FOR THE THERAPY AND DIAGNOSIS OF PROSTATE CANCER
- 专利标题(中): UN组合工艺可用于治疗和诊断前列腺癌
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申请号: EP01922786.7申请日: 2001-03-27
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公开(公告)号: EP1311673A2公开(公告)日: 2003-05-21
- 发明人: XU, Jiangchun , DILLON, Davin, C. , MITCHAM, Jennifer, L. , HARLOCKER, Susan, L. , JIANG, Yuqiu , KALOS, Michael, D. , FANGER, Gary, Richard , RETTER, Marc, W. , STOLK, John, A. , DAY, Craig, H. , VEDVICK, Thomas, S. , CARTER, Darrick , LI, Samuel, X. , WANG, Aijun , SKEIKY, Yasir, A., W. , HEPLER, William, T. , HENDERSON, Robert, A.
- 申请人: CORIXA CORPORATION
- 申请人地址: Suite 200,1124 Columbia Street Seattle, WA 98104 US
- 专利权人: CORIXA CORPORATION
- 当前专利权人: CORIXA CORPORATION
- 当前专利权人地址: Suite 200,1124 Columbia Street Seattle, WA 98104 US
- 代理机构: Gowshall, Jonathan Vallance
- 优先权: US536857 20000327; US568100 20000509; US570737 20000512; US593793 20000613; US605783 20000627; US636215 20000810; US651236 20000829; US657279 20000906; US679426 20001002; US685166 20001010; US709729 20001109
- 国际公布: WO01073032 20011004
- 主分类号: C12N15/12
- IPC分类号: C12N15/12 ; C07K14/47 ; C12N1/21 ; C12N5/10 ; C07K16/18 ; G01N33/68 ; C07K19/00 ; C12N15/10 ; A61K38/17 ; A61K31/70 ; A61K39/395 ; A61K35/14 ; C12Q1/68
摘要:
Compositions and methods for the therapy and diagnosis of cancer, particularly prostate cancer, are disclosed. Illustrative compositions comprise one or more prostate-specific polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly prostate cancer.
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