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1.发明公开
公开(公告)号：EP1299417A2
公开(公告)日：2003-04-09
申请号：EP01928521.2
申请日：2001-04-12
申请人： CORIXA CORPORATION
发明人： JIANG, Yuqiu , DILLON, Davin, C. , MITCHAM, Jennifer, L. , XU, Jiangchun , HARLOCKER, Susan, L. , HEPLER, William, T.
CPC分类号： C07K14/47 , A61K35/12 , A61K38/00 , A61K39/00 , A61K2039/5154 , A61K2039/57 , C07K14/4748 , C07K2319/00 , C12N9/00 , C12Q1/6886 , C12Q2600/158 , Y10S977/924
摘要： Compositions and methods for the therapy and diagnosis of cancer, such as breast cancer, are disclosed. Compositions may comprise one or more breast tumor proteins, immunogenic portions thereof, or polynucleotides that encode such portions. Alternatively, a therapeutic composition may comprise an antigen presenting cell that expresses a breast tumor protein, or a T cell that is specific for cells expressing such a protein. Such compositions may be used, for example, for the prevention and treatment of diseases such as breast cancer. Diagnostic methods based on detecting a breast tumor protein, or mRNA encoding such a protein, in a sample are also provided.
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2.发明公开
公开(公告)号：EP1287028A2
公开(公告)日：2003-03-05
申请号：EP01946179.7
申请日：2001-06-08
申请人： CORIXA CORPORATION
IPC分类号： C07K14/47
CPC分类号： C07K14/4748 , A61K38/00 , A61K39/00 , A61K2039/505 , C07K2319/00 , C12Q1/6886 , C12Q2600/158
摘要： Compositions and methods for the therapy and diagnosis of cancer, such as colon cancer, are disclosed. Compositions may comprise one or more colon tumor proteins, immunogenic portions thereof, or polynucleotides that encode such portions. Alternatively, a therapeutic composition may comprise an antigen presenting cell that expresses a colon tumor protein, or a T cell that is specific for cells expressing such a protein. Such compositions may be used, for example, for the prevention and treatment of diseases such as colon cancer. Diagnostic methods based on detecting a colon tumor protein, or mRNA encoding such a protein, in a sample are also provided.
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3.发明授权COMPOSITIONS FOR THE TREATMENT AND DIAGNOSIS OF BREAST CANCER AND METHODS FOR THEIR USE 有权组合物用于治疗和乳腺癌和利用方式诊断THEREOF
公开(公告)号：EP1183348B1
公开(公告)日：2011-06-29
申请号：EP00919352.5
申请日：2000-02-15
申请人： CORIXA CORPORATION
发明人： YUQIU, Jiang , DILLON, Davin, C. , MITCHAM, Jennifer, Lynn , XU, Jiangchun , HARLOCKER, Susan, L.
IPC分类号： C12N15/12 , C12N15/52 , C07K14/47 , C12N9/00 , C12N5/10 , C12N1/21 , A61K38/17 , A61K39/00 , C07K16/30 , C07K16/32 , C07K16/40 , A61K39/395 , A61K35/12 , C07K19/00 , C12N15/62 , C12N5/00 , G01N33/68 , C12Q1/68 , C12N15/11
CPC分类号： C07K14/47 , A61K35/12 , A61K38/00 , A61K39/00 , C07K2319/00 , C12N9/00 , C12Q1/6886 , C12Q2600/158
摘要： Compositions and methods for the therapy and diagnosis of cancer, such as breast cancer, are disclosed. Compositions may comprise one or more breast tumor proteins, immunogenic portion thereof, or polynucleotides that encode such portions. Alternatively, a therapeutic composition may comprise an antigen presenting cell that expresses a breast tumor protein, or a T cell that is specific for cells expressing such a protein. Such compositions may be used, for example, for the prevention and treatment of diseases such as breast cancer. Diagnostic methods based on detecting a breast tumor protein, or mRNA encoding such a protein, in a sample are also provided.
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4.发明公开
公开(公告)号：EP1515982A2
公开(公告)日：2005-03-23
申请号：EP02725984.5
申请日：2002-05-09
申请人： CORIXA CORPORATION
发明人： XU, Jiangchun , DILLON, Davin, C. , MITCHAM, Jennifer, L. , HARLOCKER, Susan, L. , JIANG, Yuqiu , HENDERSON, Robert, A. , KALOS, Michael, D. , FANGER, Gary, R. , RETTER, Marc, W. , STOLK, John, A. , DAY, Craig, H. , VEDVICK, Thomas, S. , CARTER, Darrick , LI, Samuel, X. , WANG, Aijun , SKEIKY, Yasir, A., W. , HEPLER, William, T. , HURAL, John , MCNEILL, Patricia, D. , HOUGHTON, Raymond L. Carlota , VINALS Y DE BASSOLS, Carlota , FOY, Teresa M. , WATANABE, Yoshihiro , DENG, Ta
CPC分类号： C07K16/3069 , A61K39/00 , A61K2039/505 , C07K14/47 , C07K2317/34 , C07K2319/00
摘要： Compositions and methods for the therapy and diagnosis of cancer, particularly prostate cancer, are disclosed. Illustrative compositions comprise one or more prostate-specific polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly prostate cancer.
摘要翻译： 披露了用于治疗和诊断癌症，特别是前列腺癌的组合物和方法。 说明性组合物包含一种或多种前列腺特异性多肽，其免疫原性部分，编码此类多肽的多核苷酸，表达此类多肽的抗原呈递细胞和对表达此类多肽的细胞具有特异性的T细胞。 所公开的组合物可用于例如疾病的诊断，预防和/或治疗，特别是前列腺癌。
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5.发明公开COMPOSITIONS AND METHODS FOR THE THERAPY AND DIAGNOSIS OF BREAST CANCER 审中-公开ZUSAMMENSETZUNGEN UND VERFAHREN ZUR BEHANDLUNG UND诊断VON BRUSTKREBS
公开(公告)号：EP1283885A2
公开(公告)日：2003-02-19
申请号：EP01939366.9
申请日：2001-05-22
申请人： CORIXA CORPORATION
发明人： FRUDAKIS, Tony, N. , REED, Steven, G. , SMITH, John, M. , MISHER, Lynda, E. , DILLON, Davin, C. , RETTER, Marc, W. , WANG, Aijun , SKEIKY, Yasir, A., W. , HARLOCKER, Susan, L. , DAY, Craig, H.
CPC分类号： C07K14/005 , A61K35/12 , A61K38/00 , A61K39/00 , A61K48/00 , A61K2039/505 , A61K2039/5154 , A61K2039/53 , A61K2039/57 , C07K14/47 , C07K14/82 , C07K2319/00 , C12N2740/10022 , C12Q1/6886 , C12Q2600/158
摘要： Compositions and methods for the therapy and diagnosis of cancer, particularly breast cancer, are disclosed. Illustrative compositions comprise one or more breast tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly breast cancer.
摘要翻译： 公开了用于治疗和诊断癌症，特别是乳腺癌的组合物和方法。 示例性组合物包含一种或多种乳腺肿瘤多肽，其免疫原性部分，编码此类多肽的多核苷酸，表达此类多肽的抗原呈递细胞，以及对表达此类多肽的细胞特异的T细胞。 所公开的组合物可用于例如疾病，特别是乳腺癌的诊断，预防和/或治疗。
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6.发明公开
公开(公告)号：EP1356092A2
公开(公告)日：2003-10-29
申请号：EP01939819.7
申请日：2001-05-29
申请人： CORIXA CORPORATION
IPC分类号： C12Q1/68 , G01N33/574 , A61K39/00 , C12N5/06 , C12N5/08
CPC分类号： G01N33/57449 , A61K39/0011 , A61K2039/505 , A61K2039/515 , C07K16/3069 , C12Q1/6886 , C12Q2600/158
摘要： Compositions and methods for the therapy and diagnosis of cancer, particularly ovarian cancer, are disclosed. Illustrative compositions comprise one or more ovarian tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly ovarian cancer.
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公开(公告)号：EP1290171A2
公开(公告)日：2003-03-12
申请号：EP01941636.1
申请日：2001-05-25
申请人： CORIXA CORPORATION
发明人： HARLOCKER, Susan, L. , WANG, Tongtong , BANGUR, Chaitanya, S. , KLEE, Jennifer, Irmela , SWITZER, Ann
IPC分类号： C12N15/12 , C12N15/62 , C07K14/47 , C07K16/30 , C12Q1/68 , G01N33/53 , G01N33/574 , A61K39/00 , A61K39/395 , A61P35/00
CPC分类号： A61K39/0011 , A61K2039/505 , A61K2039/515 , C07K14/47 , C07K16/3023 , C07K2319/00 , C12Q1/6886
摘要： Compositions and methods for the therapy and diagnosis of cancer, particularly lung cancer, are disclosed. Illustrative compositions comprise one or more lung tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly lung cancer.
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8.发明公开COMPOSITIONS AND METHODS FOR THE THERAPY AND DIAGNOSIS OF PROSTATE CANCER 审中-公开组合物和方法治疗和诊断PROSTATKREBS的
公开(公告)号：EP1261708A2
公开(公告)日：2002-12-04
申请号：EP01906582.0
申请日：2001-01-16
申请人： CORIXA CORPORATION
发明人： XU, Jiangchun , DILLON, Davin, C. , MITCHAM, Jennifer, L. , HARLOCKER, Susan, L. , JIANG, Yuqiu , REED, Steven, G. , KALOS, Michael, D. , FANGER, Gary, Richard , DAY, Craig, H. , RETTER, Marc, W. , STOLK, John, A. , SKEIKY, Yasir, A.W. , WANG, Aijun , MEAGHER, Madeleine, Joy
IPC分类号： C12N15/12 , C12N15/11 , C12N1/21 , C12N5/10 , C07K14/47 , C07K16/18 , C07K19/00 , A61K38/17 , A61K48/00 , G01N33/68 , C12Q1/68 , C12N5/08
CPC分类号： C07K14/005 , A61K39/00 , A61K2039/53 , C07K2319/00 , C12N9/6424 , C12N2760/16022
摘要： Compositions and methods for the therapy and diagnosis of cancer, particularly prostate cancer, are disclosed. Illustrative compositions comprise one or more prostate-specific polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly prostate cancer.
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9.发明公开
公开(公告)号：EP1363929A2
公开(公告)日：2003-11-26
申请号：EP02723095.2
申请日：2002-02-04
申请人： CORIXA CORPORATION
发明人： DILLON, Davin, C. , DAY, Craig, H. , JIANG, Yuqiu , HOUGHTON, Raymond, L. , MITCHAM, Jennifer, L. , WANG, Tongtong , MCNEILL, Patricia, D. , HARLOCKER, Susan, L. , BENNINGTON, Angela, Ann , ZEHENTNER, Barbara , FANGER, Gary, R. , RETTER, Marc, W.
CPC分类号： C07K14/4748 , A61K38/00 , A61K39/00 , A61K2039/5154 , A61K2039/5156 , A61K2039/5158 , C07K14/47 , C07K2319/00 , G01N33/57415
摘要： Compositions and methods for the therapy and diagnosis of cancer, particularly breastcancer, are disclosed. Illustrative compositions comprise one or more breasttumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly breastcancer.
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10.发明公开
公开(公告)号：EP1311673A2
公开(公告)日：2003-05-21
申请号：EP01922786.7
申请日：2001-03-27
申请人： CORIXA CORPORATION
发明人： XU, Jiangchun , DILLON, Davin, C. , MITCHAM, Jennifer, L. , HARLOCKER, Susan, L. , JIANG, Yuqiu , KALOS, Michael, D. , FANGER, Gary, Richard , RETTER, Marc, W. , STOLK, John, A. , DAY, Craig, H. , VEDVICK, Thomas, S. , CARTER, Darrick , LI, Samuel, X. , WANG, Aijun , SKEIKY, Yasir, A., W. , HEPLER, William, T. , HENDERSON, Robert, A.
IPC分类号： C12N15/12 , C07K14/47 , C12N1/21 , C12N5/10 , C07K16/18 , G01N33/68 , C07K19/00 , C12N15/10 , A61K38/17 , A61K31/70 , A61K39/395 , A61K35/14 , C12Q1/68
CPC分类号： C07K14/47
摘要： Compositions and methods for the therapy and diagnosis of cancer, particularly prostate cancer, are disclosed. Illustrative compositions comprise one or more prostate-specific polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly prostate cancer.
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