Invention Grant
- Patent Title: Chromatography ligand
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Application No.: US15882998Application Date: 2018-01-29
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Publication No.: US10751645B2Publication Date: 2020-08-25
- Inventor: Carina Engstrand , Annika Forss , Gunnar Glad , Bo-Lennart Johansson , Hans J Johansson , Jean-Luc Maloisel
- Applicant: GE Healthcare BioProcess R&D AB
- Applicant Address: SE Uppsala
- Assignee: GE Healthcare BioProcess R&D AB
- Current Assignee: GE Healthcare BioProcess R&D AB
- Current Assignee Address: SE Uppsala
- Agency: Eversheds Sutherland (US) LLP
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@1d01f2e9 com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@1c5d6e6d
- Main IPC: B01D15/38
- IPC: B01D15/38 ; B01D15/32 ; B01D15/36 ; B01J20/32 ; B01J20/286 ; B01J41/20 ; C07K1/36 ; C07K16/06 ; C07K1/16 ; C07K16/00

Abstract:
The present invention relates to a chromatography ligand defined by the following formula R1—R2—N(R3)—R4—R5 wherein R1 is a substituted or non-substituted phenyl group; R2 is a hydrocarbon chain comprising 0-4 carbon atoms; R3 is a hydrocarbon chain comprising 1-3 carbon atoms; R4 is a hydrocarbon chain comprising 1-5 carbon atoms; and R5 is OH or H. The invention also comprises a separation matrix, comprising the described ligands coupled to a porous support, such as particles or a membrane. The ligand and matrix according to the invention is useful for purification of biomolecules or organic compounds, such as proteins, polypeptides, DNA etc. An advantageous use according to the invention is the purification of antibodies.
Public/Granted literature
- US20180154281A1 CHROMATOGRAPHY LIGAND Public/Granted day:2018-06-07
Information query
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