Invention Grant
- Patent Title: Mesenchymal stem cell-derived exosomes and their uses
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Application No.: US15772668Application Date: 2016-11-02
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Publication No.: US11857575B2Publication Date: 2024-01-02
- Inventor: Olga De La Rosa , Eleuterio Lombardo , Wilfried Dalemans , Javier Garcia Casado , Rebeca Blazquez Duran , Francisco Miguel Sanchez Margallo
- Applicant: Takeda Pharmaceutical Company Limited
- Applicant Address: JP Osaka
- Assignee: TAKEDA PHARMACEUTICAL COMPANY LIMITED
- Current Assignee: TAKEDA PHARMACEUTICAL COMPANY LIMITED
- Current Assignee Address: JP Osaka
- Agency: Greer, Burns & Crain, Ltd.
- International Application: PCT/EP2016/076462 2016.11.02
- International Announcement: WO2017/076924A 2017.05.11
- Date entered country: 2018-05-01
- Main IPC: A61K35/02
- IPC: A61K35/02 ; A61K9/127 ; A61K9/50 ; C12N15/62 ; A61P29/00 ; A61P37/06 ; A61K45/06 ; A61K35/35 ; A61K31/519 ; A61K31/4709 ; A61K31/444 ; A61K31/4439 ; A61K31/5377 ; G01N1/40 ; C12N5/0775 ; A61K35/12 ; A61K35/28
Abstract:
The invention relates to exosomes derived from mesenchymal stem cells and well as isolated populations of said exosomes and method for preparing said isolated exosome populations. The invention also relates to a pharmaceutical composition comprising said exosome or isolated exosome population and their use in a method of treating an immune-mediated inflammatory disease in a subject.
Public/Granted literature
- US20180318354A1 MESENCHYMAL STEM CELL-DERIVED EXOSOMES AND THEIR USES Public/Granted day:2018-11-08
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