Invention Application
- Patent Title: Inhibitors of cathepsin S
-
Application No.: US10922515Application Date: 2004-08-18
-
Publication No.: US20050113356A1Publication Date: 2005-05-26
- Inventor: Hong Liu , Arnab Chatterjee , David Tully , Phillip Alper , Badry Bursulaya , Jianhua Guo , David Woodmansee , Daniel Mutnick , Donald Karanewsky , Yun He
- Applicant: Hong Liu , Arnab Chatterjee , David Tully , Phillip Alper , Badry Bursulaya , Jianhua Guo , David Woodmansee , Daniel Mutnick , Donald Karanewsky , Yun He
- Applicant Address: BM Hamilton
- Assignee: IRM LLC
- Current Assignee: IRM LLC
- Current Assignee Address: BM Hamilton
- Main IPC: A61K
- IPC: A61K20060101 ; A61K31/397 ; A61K31/401 ; A61K31/404 ; A61K31/423 ; A61K31/445 ; A61K31/454 ; A61K31/495 ; A61K31/537 ; A61K31/5375 ; A61K31/54 ; C07D209/04 ; C07D209/08 ; C07D261/14 ; C07D265/30 ; C07D295/13 ; C07D295/18 ; C07D295/20 ; C07D411/12 ; C07D413/12 ; C07D417/12
Abstract:
The present invention provides compounds, compositions and methods for the selective inhibition of cathepsin S. In a preferred aspect, cathepsin S is selectively inhibited in the presence of at least one other cathepsin isozyme. The present invention also provides methods for treating a disease state in a subject by selectively inhibiting cathepsin S.
Public/Granted literature
- US07314872B2 Inhibitors of cathepsin S Public/Granted day:2008-01-01
Information query
