Invention Application
US20080085890A1 Substituted isoquinoline-1,3(2H,4H)-diones, 1-thioxo-1,4-dihydro-2H-isoquinoline-3-ones and 1,4-dihydro-3 (2H)-isoquinolones and methods of use thereof
失效
取代的异喹啉-1,3（2H，4H） - 二酮，1-硫代-1,4-二氢-2H-异喹啉-3-酮和1,4-二氢-3（2H） - 异喹诺酮及其使用方法
- Patent Title: Substituted isoquinoline-1,3(2H,4H)-diones, 1-thioxo-1,4-dihydro-2H-isoquinoline-3-ones and 1,4-dihydro-3 (2H)-isoquinolones and methods of use thereof
- Patent Title (中): 取代的异喹啉-1,3（2H，4H） - 二酮，1-硫代-1,4-二氢-2H-异喹啉-3-酮和1,4-二氢-3（2H） - 异喹诺酮及其使用方法
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Application No.: US11728897Application Date: 2007-03-26
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Publication No.: US20080085890A1Publication Date: 2008-04-10
- Inventor: Hwei-Ru Tsou , Semiramis Ayral-Kaloustian , Gary Birnberg , Middleton Floyd , Joshua Kaplan , Kristina Kutterer , Xiaoxiang Liu , Ramaswamy Nilakantan , Mercy Otteng , Zhilian Tang , Arie Zask , Tritin Tran , Scott Mayer , Annette Banker , Marvin Reich
- Applicant: Hwei-Ru Tsou , Semiramis Ayral-Kaloustian , Gary Birnberg , Middleton Floyd , Joshua Kaplan , Kristina Kutterer , Xiaoxiang Liu , Ramaswamy Nilakantan , Mercy Otteng , Zhilian Tang , Arie Zask , Tritin Tran , Scott Mayer , Annette Banker , Marvin Reich
- Applicant Address: US NJ Madison
- Assignee: Wyeth
- Current Assignee: Wyeth
- Current Assignee Address: US NJ Madison
- Main IPC: A61K31/55
- IPC: A61K31/55 ; A61K31/47 ; A61K31/496 ; A61K31/497 ; A61K31/501 ; A61P1/00 ; A61P17/06 ; A61P3/10 ; A61P31/12 ; C07D295/00 ; C07D241/02 ; C07D239/02 ; C07D237/26 ; C07D237/02 ; C07D223/02 ; C07D217/00 ; A61P9/00 ; A61P35/00 ; A61P31/10 ; A61P19/02 ; A61P11/00 ; A61K31/502 ; A61K31/506 ; A61K31/5377 ; A61K31/541
Abstract:
This invention provides compounds of Formula (I), having the structure where G1, G2, G3, G4, A1, A2, Y1, Y2, L1, Z, e and f are defined herein, or a pharmaceutically acceptable salt thereof, which are useful for treating or preventing cancer.
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