Invention Application
- Patent Title: Intracellular Delivery
- Patent Title (中): 胞内输送
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Application No.: US14352354Application Date: 2012-10-17
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Publication No.: US20140287509A1Publication Date: 2014-09-25
- Inventor: Armon R. Sharei , Andrea Adamo , Robert S. Langer , Klavs F. Jensen
- Applicant: Massachusetts Institute of Technology
- Applicant Address: US MA Cambridge US MA Cambridge
- Assignee: MASSACHUSETTS INSTITUTE OF TECHNOLOGY,MASSACHUSETTS INSTITUTE OF TECHNOLOGY
- Current Assignee: MASSACHUSETTS INSTITUTE OF TECHNOLOGY,MASSACHUSETTS INSTITUTE OF TECHNOLOGY
- Current Assignee Address: US MA Cambridge US MA Cambridge
- International Application: PCT/US12/60646 WO 20121017
- Main IPC: C12N5/071
- IPC: C12N5/071
Abstract:
A microfluidic system for causing perturbations in a cell membrane, the system including a microfluidic channel defining a lumen and being configured such that a cell suspended in a buffer can pass therethrough, wherein the microfluidic channel includes a cell-deforming constriction, wherein a diameter of the constriction is a function of the diameter of the cell.
Public/Granted literature
- US10696944B2 Intracellular delivery Public/Granted day:2020-06-30
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