Invention Application
- Patent Title: Self-Antigen Displaying Nanoparticles Targeting Auto-Reactive Immune Factors and Uses Thereof
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Application No.: US15505148Application Date: 2015-08-20
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Publication No.: US20170274059A1Publication Date: 2017-09-28
- Inventor: Liangfang Zhang , Che-Ming Jack Hu , Jonathan Copp , Ronnie H. Fang , Brian T. Luk
- Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
- International Application: PCT/US15/46016 WO 20150820
- Main IPC: A61K39/00
- IPC: A61K39/00 ; A61K45/06 ; A61K47/34
Abstract:
The invention provides a composition, and method of use thereof, comprising self-antigen displaying nanoparticles to target auto-reactive immune components for treating and/or preventing the autoimmune diseases associated therewith. The nanoparticles can also be loaded with cytotoxic drugs for targeted cell killing or with immune-tolerizing compounds to normalize the immune regulation.
Public/Granted literature
- US12285472B2 Self-antigen displaying nanoparticles targeting auto-reactive immune factors and uses thereof Public/Granted day:2025-04-29
Information query
