- 专利标题: LABELLED NUCLEOTIDES
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申请号: US17034725申请日: 2020-09-28
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公开(公告)号: US20210009622A1公开(公告)日: 2021-01-14
- 发明人: Xiaohai LIU , John MILTON , Silke RUEDIGER , Xiaolin WU
- 申请人: Illumina Cambridge Limited
- 申请人地址: GB Cambridge
- 专利权人: Illumina Cambridge Limited
- 当前专利权人: Illumina Cambridge Limited
- 当前专利权人地址: GB Cambridge
- 主分类号: C07H19/04
- IPC分类号: C07H19/04 ; C07H19/16 ; C07H19/20 ; C07H19/14 ; C07H19/06 ; C12Q1/6874 ; C07H21/00 ; C07H19/10 ; C12Q1/6869 ; C07H21/04
摘要:
The invention provides a nucleotide or nucleoside having a base attached to a detectable label via a cleavable linker, characterised in that the cleavable linker contains a moiety selected from the group comprising: Formula (I) (wherein X is selected from the group comprising O, S, NH and NQ wherein Q is a C1-10 substituted or unsubstituted alkyl group, Y is selected from the group comprising O, S, NH and N(allyl), T is hydrogen or a C1-10 substituted or unsubstituted alkyl group and * indicates where the moiety is connected to the remainder of the nucleotide or nucleoside).
公开/授权文献
- US11028115B2 Labelled nucleotides 公开/授权日:2021-06-08
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