发明公开
![1H-PYRAZOLO[4,3-d]PYRIMIDINE COMPOUNDS AS TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS](/docs/US/2023-05-11/US20230144824A1/abs.jpg.600x600.jpg)
- 专利标题： 1H-PYRAZOLO[4,3-d]PYRIMIDINE COMPOUNDS AS TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS
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申请号： US17793248申请日： 2021-01-26
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公开(公告)号： US20230144824A1公开(公告)日： 2023-05-11
- 发明人: Liqi HE , Ashvinikumar V. GAVAI , Sanjeev GANGWAR , Qiang CONG , Yam B. POUDEL , Prasanna SIVAPRAKASAM , Christine M. TARBY , Patrice GILL , Andrew F. DONNELL , Murugaiah ANDAPPAN MURUGAIAH SUBBAIAH
- 申请人： BRISTOL-MYERS SQUIBB COMPANY
- 申请人地址： US NJ Princeton
- 专利权人： BRISTOL-MYERS SQUIBB COMPANY
- 当前专利权人： BRISTOL-MYERS SQUIBB COMPANY
- 当前专利权人地址： US NJ Princeton
- 国际申请： PCT/US2021/014983 2021.01.26
- 进入国家日期： 2022-07-15
- 主分类号： C07D487/04
- IPC分类号： C07D487/04
![1H-PYRAZOLO[4,3-d]PYRIMIDINE COMPOUNDS AS TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS](/abs-image/US/2023/05/11/US20230144824A1/abs.jpg.150x150.jpg)
摘要：
Compounds according to formula I or II are useful as agonists of Toll-like receptor 7 (TLR7). Such compounds can be used in cancer treatment, especially in combination with an anti-cancer immunotherapy agent, or as a vaccine adjuvant.
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