Invention Grant
- Patent Title: Exocrine gland tight junction-constituting protein jeap family
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Application No.: US10298417Application Date: 2002-11-15
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Publication No.: US07129063B2Publication Date: 2006-10-31
- Inventor: Miyuki Nishimura , Mayumi Asano , Yuichi Ono , Koji Morimoto , Masakazu Takeuchi , Yoko Inoue , Toshio Imai , Yoshimi Takai
- Applicant: Miyuki Nishimura , Mayumi Asano , Yuichi Ono , Koji Morimoto , Masakazu Takeuchi , Yoko Inoue , Toshio Imai , Yoshimi Takai
- Applicant Address: JP Tokyo
- Assignee: Eisai Co., Ltd.
- Current Assignee: Eisai Co., Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Choate, Hall & Stewart, LLP
- Priority: JP2001-352241 20011116
- Main IPC: C12P21/02
- IPC: C12P21/02 ; C12N15/63 ; C12N1/21 ; C12N1/19 ; C12N5/10 ; C07H21/04
Abstract:
A mouse cDNA library from gene fragments encoding proteins localizing at cell-cell junctions was screened by a technique visualizing localization of a protein to to identify a junction-enriched and -associated protein, JEAP. GenBank homology search was performed based on the sequence. Based on the obtained sequence, a mouse cDNA library was screened to identify JEAP-2. By using prepared antibodies against these proteins, it was revealed that these proteins express specifically at tight junctions, in particular, tight junctions in exocrine glands.
Public/Granted literature
- US20030124603A1 Exocrine gland tight junction-constituting protein jeap family Public/Granted day:2003-07-03
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