发明授权
- 专利标题： Genetic suppression and replacement
- 专利标题（中）： 遗传抑制和替代
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申请号： US12595080申请日： 2008-04-14
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公开(公告)号： US08257969B2公开(公告)日： 2012-09-04
- 发明人: Gwyneth Jane Farrar , Sophia Millington-Ward , Naomi Chadderton , Arpad Palfi , Mary O'Reilly , Paul Kenna , Peter Humphries
- 申请人： Gwyneth Jane Farrar , Sophia Millington-Ward , Naomi Chadderton , Arpad Palfi , Mary O'Reilly , Paul Kenna , Peter Humphries
- 申请人地址： IE Dublin
- 专利权人： The Provost Fellows and Scholars of the College of the Holy and Undivided Trinity of Queen Elizabeth
- 当前专利权人： The Provost Fellows and Scholars of the College of the Holy and Undivided Trinity of Queen Elizabeth
- 当前专利权人地址： IE Dublin
- 代理机构： Nixon Peabody LLP
- 代理商 David S. Resnick; Leena H. Karttunen Contarino
- 国际申请： PCT/GB2008/001310 WO 20080414
- 国际公布： WO2008/125846 WO 20081023
- 主分类号： C12N15/00
- IPC分类号： C12N15/00 ; C12N5/00
摘要：
The invention relates to gene suppression and replacement. In particular, the invention relates to enhanced expression of suppression agents for suppressing gene expression in a cell and in vivo and replacement nucleic acids that are not inhibited by the suppression agent. Regulatory elements are included in expression vectors to optimize expression of the suppression agent and/or replacement nucleic acid.
公开/授权文献
- US20100190841A1 GENETIC SUPPRESSION AND REPLACEMENT 公开/授权日：2010-07-29
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