Invention Grant
- Patent Title: Compounds
- Patent Title (中): 化合物
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Application No.: US12908172Application Date: 2010-10-20
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Publication No.: US08951999B2Publication Date: 2015-02-10
- Inventor: Henning Priepke , Henri Doods , Raimund Kuelzer , Roland Pfau , Dirk Stenkamp , Robert Roenn , Benjamin Pelcman
- Applicant: Henning Priepke , Henri Doods , Raimund Kuelzer , Roland Pfau , Dirk Stenkamp , Robert Roenn , Benjamin Pelcman
- Applicant Address: SE Stockholm
- Assignee: Orexo AB
- Current Assignee: Orexo AB
- Current Assignee Address: SE Stockholm
- Priority: EP09173872 20091023
- Main IPC: A61K31/445
- IPC: A61K31/445 ; C07D211/32 ; C07C311/14 ; C07D213/82 ; C07C237/42 ; C07C237/44 ; C07C255/23 ; C07C255/60 ; C07D205/04 ; C07D207/10 ; C07D207/22 ; C07D207/34 ; C07D209/08 ; C07D211/14 ; C07D211/16 ; C07D211/18 ; C07D211/38 ; C07D213/40 ; C07D213/75 ; C07D213/81 ; C07D215/42 ; C07D237/30 ; C07D277/46 ; C07D277/56 ; C07D277/60 ; C07D277/82 ; C07D295/15 ; C07D295/155 ; C07D307/20 ; C07D307/24 ; C07D309/12 ; C07D309/14 ; C07D333/38 ; C07D335/02 ; C07D417/04
Abstract:
This invention relates to compounds of formula I, their use as inhibitors of the microsomal prostaglandin E2 synthase-1 (mPGES-1), pharmaceutical compositions containing them, and their use as medicaments for the treatment and/or prevention of inflammatory diseases and associated conditions such as inflammatory/nociceptive pain. A, M, R1, R2, R7, Ra, Rb, Q3, Q4, Q6, Z2, Z4, Z5, Z6 and W have meanings given in the description.
Public/Granted literature
- US20110263556A1 New Compounds Public/Granted day:2011-10-27
Information query
IPC分类:
