发明授权
- 专利标题: Labelled nucleotides
- 专利标题(中): 标记核苷酸
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申请号: US14821592申请日: 2015-08-07
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公开(公告)号: US09410199B2公开(公告)日: 2016-08-09
- 发明人: Xiaohai Liu , John Milton , Silke Ruediger
- 申请人: Illumina Cambridge Limited
- 申请人地址: GB Nr.Saffron Walden
- 专利权人: Illumina Cambridge Limited
- 当前专利权人: Illumina Cambridge Limited
- 当前专利权人地址: GB Nr.Saffron Walden
- 代理机构: Jones Day
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68 ; C12P19/34 ; C07H21/04 ; C07H19/06 ; C07H19/10 ; C07H19/16 ; C07H19/20 ; C07H21/00
摘要:
The invention provides a nucleotide or nucleoside having a base attached to a detectable label via a cleavable linker, characterized in that the cleavable linker contains a moiety selected from the group comprising: Formula (I) (wherein X is selected from the group comprising O, S, NH and NQ wherein Q is a C1-10 substituted or unsubstituted alkyl group, Y is selected from the group comprising O, S, NH and N(allyl), T is hydrogen or a C1-10 substituted or unsubstituted alkyl group and * indicates where the moiety is connected to the remainder of the nucleotide or nucleoside).
公开/授权文献
- US20150344516A1 LABELLED NUCLEOTIDES 公开/授权日:2015-12-03