Invention Grant
US09452415B2 Sorbent comprising on its surface a cationic or protonizable aliphatic residue for the purification of organic molecules
有权
吸附剂在其表面上包含用于纯化有机分子的阳离子或可质子化的脂族残基
- Patent Title: Sorbent comprising on its surface a cationic or protonizable aliphatic residue for the purification of organic molecules
- Patent Title (中): 吸附剂在其表面上包含用于纯化有机分子的阳离子或可质子化的脂族残基
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Application No.: US14344718Application Date: 2012-09-17
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Publication No.: US09452415B2Publication Date: 2016-09-27
- Inventor: Markus Arendt , Björn Degel , Thomas Schwarz , Gerhard Stumm , Martin Welter
- Applicant: INSTRACTION GMBH
- Applicant Address: DE Mannheim
- Assignee: INSTRACTION GMBH
- Current Assignee: INSTRACTION GMBH
- Current Assignee Address: DE Mannheim
- Agency: Hueschen and Sage
- Priority: EP11181412 20110915
- International Application: PCT/EP2012/068198 WO 20120917
- International Announcement: WO2013/037994 WO 20130321
- Main IPC: B01J20/22
- IPC: B01J20/22 ; B01J20/286 ; B01D15/38 ; B01J20/32 ; C07D313/00 ; C07B63/00 ; C07D305/14 ; C07H3/02 ; C07H17/08 ; C07D215/18 ; C07D493/22 ; C07C37/82 ; A61K31/337 ; A61K31/365 ; A61K31/47 ; A61K31/573 ; A61K31/724 ; C07C211/09 ; C07C215/12 ; C07C225/06 ; C07D295/185
Abstract:
The present invention relates to a sorbent comprising a solid support material, the surface of which comprises a residue of a general formula (I), wherein the residue is attached via a covalent single bond to a functional group on the surface of either the bulk solid support material itself or of a polymer film on the surface of the solid support material. Furthermore, the present invention relates to the use of the sorbent according to the invention for the purification of organic molecules, in particular pharmaceutically active compounds, preferably in chromatographic application.
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