公开(公告)号：US20150045545A1

公开(公告)日：2015-02-12

申请号：US14344171

申请日：2012-09-17

Applicant: INSTRACTION GMBH

Inventor： Markus Arendt ,  Björn Degel ,  Thomas Schwarz ,  Gerhard Stumm ,  Martin Welter

IPC: B01J20/289 ,  C07H15/248 ,  C07H1/06 ,  C07H17/08

CPC classification number: B01J20/289 ,  A61K31/7032 ,  A61K31/7036 ,  B01J20/288 ,  B01J20/3219 ,  B01J20/3253 ,  B01J20/328 ,  B01J20/3282 ,  B01J20/3285 ,  B01J2220/80 ,  C07H1/06 ,  C07H15/248 ,  C07H17/08

Abstract: The present invention relates to a sorbent comprising a solid support material, the surface of which comprises a residue of a general formula (I), wherein the residue is attached via a covalent single bond to a functional group on the surface of either the bulk solid support material itself or of a polymer film on the surface of the solid support material. Furthermore, the present invention relates to the use of the sorbent according to the invention for the purification of organic molecules, in particular pharmaceutically active compounds, preferably in chromatographic applications.

Abstract translation: 本发明涉及包含固体支持材料的吸附剂，其表面包含通式（I）的残基，其中所述残基通过共价单键连接到本体固体的表面上的官能团 支撑材料本身或固体支撑材料表面上的聚合物膜。 此外，本发明涉及根据本发明的吸附剂用于纯化有机分子，特别是药学活性化合物，优选在色谱应用中的用途。

公开(公告)号：US20150005487A1

公开(公告)日：2015-01-01

申请号：US14344718

申请日：2012-09-17

Applicant: INSTRACTION GMBH

Inventor： Markus Arendt ,  Björn Degel ,  Thomas Schwarz ,  Gerhard Stumm ,  Martin Welter

IPC: B01J20/286 ,  A61K31/47 ,  C07C215/12 ,  A61K31/573 ,  C07C225/06 ,  A61K31/337 ,  A61K31/724 ,  A61K31/365 ,  C07C211/09 ,  C07D295/185

CPC classification number: B01J20/286 ,  A61K31/337 ,  A61K31/365 ,  A61K31/47 ,  A61K31/573 ,  A61K31/724 ,  B01D15/3804 ,  B01J20/3219 ,  B01J20/3248 ,  B01J20/3253 ,  B01J20/3255 ,  B01J20/328 ,  B01J20/3285 ,  B01J2220/80 ,  C07B63/00 ,  C07C37/82 ,  C07C211/09 ,  C07C215/12 ,  C07C225/06 ,  C07D215/18 ,  C07D295/185 ,  C07D305/14 ,  C07D313/00 ,  C07D493/22 ,  C07H3/02 ,  C07H17/08 ,  C07C39/30

Abstract: The present invention relates to a sorbent comprising a solid support material, the surface of which comprises a residue of a general formula (I), wherein the residue is attached via a covalent single bond to a functional group on the surface of either the bulk solid support material itself or of a polymer film on the surface of the solid support material. Furthermore, the present invention relates to the use of the sorbent according to the invention for the purification of organic molecules, in particular pharmaceutically active compounds, preferably in chromatographic application.

Abstract translation: 本发明涉及包含固体支持材料的吸附剂，其表面包含通式（I）的残基，其中所述残基通过共价单键连接到本体固体的表面上的官能团 支撑材料本身或固体支撑材料表面上的聚合物膜。 此外，本发明涉及根据本发明的吸着剂用于纯化有机分子，特别是药学活性化合物，优选在色谱应用中的用途。

公开(公告)号：US11014071B1

公开(公告)日：2021-05-25

申请号：US15777967

申请日：2016-11-25

Applicant: instrAction GmbH

Inventor： Martin Welter ,  Christian Meyer ,  Kristian Lungfiel ,  Thomas Schwarz

IPC: B01D15/08 ,  B01D15/38 ,  B01J20/26 ,  B01J20/28 ,  B01J20/285 ,  B01J20/30 ,  B01J20/32 ,  C02F1/28 ,  C08J3/075 ,  B01D15/36 ,  C02F101/30 ,  C02F101/20

Abstract: A method for producing porous particles of a cross-linked polymer, and porous particles that can be produced according to the method are disclosed. The porous particles of a crosslinked hydroxy- or amino-group-containing polymer have a relatively low swelling factor. A composite material contains the porous particles dispersed in a continuous aqueous phase. The porous particles, or the composite material, are used for purifying organic molecules and for bonding metals from solutions. A filter cartridge contains the porous particles of a cross-linked polymer or the composite material.

公开(公告)号：US20210078889A1

公开(公告)日：2021-03-18

申请号：US16963726

申请日：2019-01-23

Applicant: instrAction GmbH

Inventor： Martin Welter ,  Christian Meyer ,  Kristian Lungfiel

IPC: C02F9/00 ,  B01D61/02 ,  B01D61/14 ,  C02F1/00

Abstract: A device for the multi-stage, modular purification of drinking water is described, wherein a module comprises a chelating gel or a chelating and a bactericidal gel for heavy metal removal and/or for heavy metal removal and bacterial removal.

公开(公告)号：US11433374B2

公开(公告)日：2022-09-06

申请号：US16735072

申请日：2020-01-06

Applicant: instrAction GmbH

Inventor： Christian Meyer ,  Martin Welter ,  Thomas Schwarz

IPC: B01J20/32 ,  C02F1/28 ,  B01J20/34 ,  C02F101/20

Abstract: The present invention relates to a sorbent which is suitable for binding metals from solutions, the production of a corresponding sorbent as well as the use of the sorbent for binding metals from solutions.

公开(公告)号：US09452415B2

公开(公告)日：2016-09-27

申请号：US14344718

申请日：2012-09-17

Applicant: INSTRACTION GMBH

Inventor： Markus Arendt ,  Björn Degel ,  Thomas Schwarz ,  Gerhard Stumm ,  Martin Welter

IPC: B01J20/22 ,  B01J20/286 ,  B01D15/38 ,  B01J20/32 ,  C07D313/00 ,  C07B63/00 ,  C07D305/14 ,  C07H3/02 ,  C07H17/08 ,  C07D215/18 ,  C07D493/22 ,  C07C37/82 ,  A61K31/337 ,  A61K31/365 ,  A61K31/47 ,  A61K31/573 ,  A61K31/724 ,  C07C211/09 ,  C07C215/12 ,  C07C225/06 ,  C07D295/185

CPC classification number: B01J20/286 ,  A61K31/337 ,  A61K31/365 ,  A61K31/47 ,  A61K31/573 ,  A61K31/724 ,  B01D15/3804 ,  B01J20/3219 ,  B01J20/3248 ,  B01J20/3253 ,  B01J20/3255 ,  B01J20/328 ,  B01J20/3285 ,  B01J2220/80 ,  C07B63/00 ,  C07C37/82 ,  C07C211/09 ,  C07C215/12 ,  C07C225/06 ,  C07D215/18 ,  C07D295/185 ,  C07D305/14 ,  C07D313/00 ,  C07D493/22 ,  C07H3/02 ,  C07H17/08 ,  C07C39/30

Abstract: The present invention relates to a sorbent comprising a solid support material, the surface of which comprises a residue of a general formula (I), wherein the residue is attached via a covalent single bond to a functional group on the surface of either the bulk solid support material itself or of a polymer film on the surface of the solid support material. Furthermore, the present invention relates to the use of the sorbent according to the invention for the purification of organic molecules, in particular pharmaceutically active compounds, preferably in chromatographic application.

Abstract translation: 本发明涉及包含固体支持材料的吸附剂，其表面包含通式（I）的残基，其中所述残基通过共价单键连接到本体固体的表面上的官能团 支撑材料本身或固体支撑材料表面上的聚合物膜。 此外，本发明涉及根据本发明的吸着剂用于纯化有机分子，特别是药学活性化合物，优选在色谱应用中的用途。

公开(公告)号：US09370766B2

公开(公告)日：2016-06-21

申请号：US14344425

申请日：2012-09-17

Applicant: INSTRACTION GMBH

Inventor： Markus Arendt ,  Björn Degel ,  Thomas Schwarz ,  Gerhard Stumm ,  Martin Welter

IPC: B01D15/32 ,  B01J20/26 ,  B01J20/32 ,  C07D498/12 ,  C07K14/625 ,  A61K31/436 ,  B01J20/287 ,  B01J20/286 ,  B01D15/38

CPC classification number: B01J20/328 ,  A61K31/436 ,  B01D15/32 ,  B01D15/327 ,  B01D15/3804 ,  B01J20/267 ,  B01J20/286 ,  B01J20/287 ,  B01J20/3219 ,  B01J20/3246 ,  B01J20/3248 ,  B01J20/3272 ,  B01J20/3282 ,  B01J20/3285 ,  C07D498/12 ,  C07K14/625

Abstract: The present invention relates to a sorbent comprising a solid support material, the surface of which comprises a residue of a general formula (I), wherein the residue is attached via a covalent single bond to a functional group on the surface of either the bulk solid support material itself or of a polymer film on the surface of the solid support material. Furthermore, the present invention relates to the use of the sorbent according to the invention for the purification of organic molecules, in particular pharmaceutically active compounds, preferably in chromatographic applications.

Abstract translation: 本发明涉及包含固体支持材料的吸附剂，其表面包含通式（I）的残基，其中所述残基通过共价单键连接到本体固体的表面上的官能团 支撑材料本身或固体支撑材料表面上的聚合物膜。 此外，本发明涉及根据本发明的吸附剂用于纯化有机分子，特别是药学活性化合物，优选在色谱应用中的用途。

公开(公告)号：US11633718B2

公开(公告)日：2023-04-25

申请号：US16641049

申请日：2018-08-01

Applicant: instrAction GmbH

Inventor： Martin Welter ,  Christian Meyer ,  Kristian Lungfiel

IPC: B01J20/26 ,  B01J20/28 ,  C02F1/28 ,  C02F1/50 ,  B01J20/32

Abstract: The present invention relates to a method for producing biocidal, porous particles of a cross-linked polymer, and to the porous particles that can be produced according to the method of the invention. The invention further relates to porous particles of an amino-group-containing polymer (polyamine) having a relatively low swelling factor. The porous particles according to the invention are used to remove biological contaminants from water and to bind metal-containing ions from solutions. The present invention further relates to a filter cartridge which contains the porous cross-linked polymer particles according to the invention.

公开(公告)号：US20220159949A1

公开(公告)日：2022-05-26

申请号：US17437279

申请日：2020-03-13

Applicant: instrAction GmbH

Inventor： Martin Welter ,  Christian Meyer ,  Kristian Lungfiel

IPC: A01N25/26 ,  B01J41/05 ,  B01J41/07 ,  B01J41/14 ,  B01J39/02 ,  B01J39/09 ,  B01J39/12 ,  A61L2/232 ,  C02F1/42 ,  C02F1/50

Abstract: Process for the preparation of particles with antibacterial coating, which comprises the following steps: (a) providing an aqueous suspension containing a polyamine, a crosslinker and a porous organic or inorganic carrier material in particle form at a temperature lower than or equal to 10° C. in a mixer for coating the inorganic carrier material with the polyamine; (b) crosslinking the organic polymer in the pores of the inorganic carrier material and simultaneously removing water.

公开(公告)号：US20150045533A1

公开(公告)日：2015-02-12

申请号：US14344425

申请日：2012-09-17

Applicant: INSTRACTION GMBH

Inventor： Markus Arendt ,  Björn Degel ,  Thomas Schwarz ,  Gerhard Stumm ,  Martin Welter

IPC: B01J20/32 ,  B01J20/286 ,  B01D15/32

CPC classification number: B01J20/328 ,  A61K31/436 ,  B01D15/32 ,  B01D15/327 ,  B01D15/3804 ,  B01J20/267 ,  B01J20/286 ,  B01J20/287 ,  B01J20/3219 ,  B01J20/3246 ,  B01J20/3248 ,  B01J20/3272 ,  B01J20/3282 ,  B01J20/3285 ,  C07D498/12 ,  C07K14/625

Abstract: The present invention relates to a sorbent comprising a solid support material, the surface of which comprises a residue of a general formula (I), wherein the residue is attached via a covalent single bond to a functional group on the surface of either the bulk solid support material itself or of a polymer film on the surface of the solid support material. Furthermore, the present invention relates to the use of the sorbent according to the invention for the purification of organic molecules, in particular pharmaceutically active compounds, preferably in chromatographic applications

Abstract translation: 本发明涉及包含固体支持材料的吸附剂，其表面包含通式（I）的残基，其中所述残基通过共价单键连接到本体固体的表面上的官能团 支撑材料本身或固体支撑材料表面上的聚合物膜。 此外，本发明涉及根据本发明的吸附剂用于纯化有机分子，特别是药学活性化合物，优选在色谱应用中的用途