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1.发明申请SORBENT COMPRISING ON ITS SURFACE AN AROMATIC RING SYSTEM HAVING AN ANIONIC OR DEPROTONIZABLE GROUP FOR THE PURIFICATION OF ORGANIC MOLECULES 审中-公开包含其表面的SORBENT具有用于纯化有机分子的ANIONO或DEPROTONIZ GROUP的芳族环系统公开(公告)号：US20150045545A1
公开(公告)日：2015-02-12
申请号：US14344171
申请日：2012-09-17
Applicant: INSTRACTION GMBH
Inventor： Markus Arendt , Björn Degel , Thomas Schwarz , Gerhard Stumm , Martin Welter
IPC: B01J20/289 , C07H15/248 , C07H1/06 , C07H17/08
CPC classification number: B01J20/289 , A61K31/7032 , A61K31/7036 , B01J20/288 , B01J20/3219 , B01J20/3253 , B01J20/328 , B01J20/3282 , B01J20/3285 , B01J2220/80 , C07H1/06 , C07H15/248 , C07H17/08
Abstract: The present invention relates to a sorbent comprising a solid support material, the surface of which comprises a residue of a general formula (I), wherein the residue is attached via a covalent single bond to a functional group on the surface of either the bulk solid support material itself or of a polymer film on the surface of the solid support material. Furthermore, the present invention relates to the use of the sorbent according to the invention for the purification of organic molecules, in particular pharmaceutically active compounds, preferably in chromatographic applications.
Abstract translation: 本发明涉及包含固体支持材料的吸附剂，其表面包含通式（I）的残基，其中所述残基通过共价单键连接到本体固体的表面上的官能团 支撑材料本身或固体支撑材料表面上的聚合物膜。 此外，本发明涉及根据本发明的吸附剂用于纯化有机分子，特别是药学活性化合物，优选在色谱应用中的用途。
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2.发明申请公开(公告)号：US20150005487A1
公开(公告)日：2015-01-01
申请号：US14344718
申请日：2012-09-17
Applicant: INSTRACTION GMBH
Inventor： Markus Arendt , Björn Degel , Thomas Schwarz , Gerhard Stumm , Martin Welter
IPC: B01J20/286 , A61K31/47 , C07C215/12 , A61K31/573 , C07C225/06 , A61K31/337 , A61K31/724 , A61K31/365 , C07C211/09 , C07D295/185
CPC classification number: B01J20/286 , A61K31/337 , A61K31/365 , A61K31/47 , A61K31/573 , A61K31/724 , B01D15/3804 , B01J20/3219 , B01J20/3248 , B01J20/3253 , B01J20/3255 , B01J20/328 , B01J20/3285 , B01J2220/80 , C07B63/00 , C07C37/82 , C07C211/09 , C07C215/12 , C07C225/06 , C07D215/18 , C07D295/185 , C07D305/14 , C07D313/00 , C07D493/22 , C07H3/02 , C07H17/08 , C07C39/30
Abstract: The present invention relates to a sorbent comprising a solid support material, the surface of which comprises a residue of a general formula (I), wherein the residue is attached via a covalent single bond to a functional group on the surface of either the bulk solid support material itself or of a polymer film on the surface of the solid support material. Furthermore, the present invention relates to the use of the sorbent according to the invention for the purification of organic molecules, in particular pharmaceutically active compounds, preferably in chromatographic application.
Abstract translation: 本发明涉及包含固体支持材料的吸附剂，其表面包含通式（I）的残基，其中所述残基通过共价单键连接到本体固体的表面上的官能团 支撑材料本身或固体支撑材料表面上的聚合物膜。 此外，本发明涉及根据本发明的吸着剂用于纯化有机分子，特别是药学活性化合物，优选在色谱应用中的用途。
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公开(公告)号：US11433374B2
公开(公告)日：2022-09-06
申请号：US16735072
申请日：2020-01-06
Applicant: instrAction GmbH
Inventor： Christian Meyer , Martin Welter , Thomas Schwarz
IPC: B01J20/32 , C02F1/28 , B01J20/34 , C02F101/20
Abstract: The present invention relates to a sorbent which is suitable for binding metals from solutions, the production of a corresponding sorbent as well as the use of the sorbent for binding metals from solutions.
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4.发明授权Sorbent comprising on its surface a cationic or protonizable aliphatic residue for the purification of organic molecules 有权吸附剂在其表面上包含用于纯化有机分子的阳离子或可质子化的脂族残基公开(公告)号：US09452415B2
公开(公告)日：2016-09-27
申请号：US14344718
申请日：2012-09-17
Applicant: INSTRACTION GMBH
Inventor： Markus Arendt , Björn Degel , Thomas Schwarz , Gerhard Stumm , Martin Welter
IPC: B01J20/22 , B01J20/286 , B01D15/38 , B01J20/32 , C07D313/00 , C07B63/00 , C07D305/14 , C07H3/02 , C07H17/08 , C07D215/18 , C07D493/22 , C07C37/82 , A61K31/337 , A61K31/365 , A61K31/47 , A61K31/573 , A61K31/724 , C07C211/09 , C07C215/12 , C07C225/06 , C07D295/185
CPC classification number: B01J20/286 , A61K31/337 , A61K31/365 , A61K31/47 , A61K31/573 , A61K31/724 , B01D15/3804 , B01J20/3219 , B01J20/3248 , B01J20/3253 , B01J20/3255 , B01J20/328 , B01J20/3285 , B01J2220/80 , C07B63/00 , C07C37/82 , C07C211/09 , C07C215/12 , C07C225/06 , C07D215/18 , C07D295/185 , C07D305/14 , C07D313/00 , C07D493/22 , C07H3/02 , C07H17/08 , C07C39/30
Abstract: The present invention relates to a sorbent comprising a solid support material, the surface of which comprises a residue of a general formula (I), wherein the residue is attached via a covalent single bond to a functional group on the surface of either the bulk solid support material itself or of a polymer film on the surface of the solid support material. Furthermore, the present invention relates to the use of the sorbent according to the invention for the purification of organic molecules, in particular pharmaceutically active compounds, preferably in chromatographic application.
Abstract translation: 本发明涉及包含固体支持材料的吸附剂，其表面包含通式（I）的残基，其中所述残基通过共价单键连接到本体固体的表面上的官能团 支撑材料本身或固体支撑材料表面上的聚合物膜。 此外，本发明涉及根据本发明的吸着剂用于纯化有机分子，特别是药学活性化合物，优选在色谱应用中的用途。
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5.发明授权Sorbent comprising on its surface an aliphatic unit for the purification of organic molecules 有权吸附剂在其表面上包含用于纯化有机分子的脂族单元公开(公告)号：US09370766B2
公开(公告)日：2016-06-21
申请号：US14344425
申请日：2012-09-17
Applicant: INSTRACTION GMBH
Inventor： Markus Arendt , Björn Degel , Thomas Schwarz , Gerhard Stumm , Martin Welter
IPC: B01D15/32 , B01J20/26 , B01J20/32 , C07D498/12 , C07K14/625 , A61K31/436 , B01J20/287 , B01J20/286 , B01D15/38
CPC classification number: B01J20/328 , A61K31/436 , B01D15/32 , B01D15/327 , B01D15/3804 , B01J20/267 , B01J20/286 , B01J20/287 , B01J20/3219 , B01J20/3246 , B01J20/3248 , B01J20/3272 , B01J20/3282 , B01J20/3285 , C07D498/12 , C07K14/625
Abstract: The present invention relates to a sorbent comprising a solid support material, the surface of which comprises a residue of a general formula (I), wherein the residue is attached via a covalent single bond to a functional group on the surface of either the bulk solid support material itself or of a polymer film on the surface of the solid support material. Furthermore, the present invention relates to the use of the sorbent according to the invention for the purification of organic molecules, in particular pharmaceutically active compounds, preferably in chromatographic applications.
Abstract translation: 本发明涉及包含固体支持材料的吸附剂，其表面包含通式（I）的残基，其中所述残基通过共价单键连接到本体固体的表面上的官能团 支撑材料本身或固体支撑材料表面上的聚合物膜。 此外，本发明涉及根据本发明的吸附剂用于纯化有机分子，特别是药学活性化合物，优选在色谱应用中的用途。
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Patent Agency Ranking
6.发明授权公开(公告)号：US11014071B1
公开(公告)日：2021-05-25
申请号：US15777967
申请日：2016-11-25
Applicant: instrAction GmbH
Inventor： Martin Welter , Christian Meyer , Kristian Lungfiel , Thomas Schwarz
IPC: B01D15/08 , B01D15/38 , B01J20/26 , B01J20/28 , B01J20/285 , B01J20/30 , B01J20/32 , C02F1/28 , C08J3/075 , B01D15/36 , C02F101/30 , C02F101/20
Abstract: A method for producing porous particles of a cross-linked polymer, and porous particles that can be produced according to the method are disclosed. The porous particles of a crosslinked hydroxy- or amino-group-containing polymer have a relatively low swelling factor. A composite material contains the porous particles dispersed in a continuous aqueous phase. The porous particles, or the composite material, are used for purifying organic molecules and for bonding metals from solutions. A filter cartridge contains the porous particles of a cross-linked polymer or the composite material.
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7.发明申请公开(公告)号：US20150045533A1
公开(公告)日：2015-02-12
申请号：US14344425
申请日：2012-09-17
Applicant: INSTRACTION GMBH
Inventor： Markus Arendt , Björn Degel , Thomas Schwarz , Gerhard Stumm , Martin Welter
IPC: B01J20/32 , B01J20/286 , B01D15/32
CPC classification number: B01J20/328 , A61K31/436 , B01D15/32 , B01D15/327 , B01D15/3804 , B01J20/267 , B01J20/286 , B01J20/287 , B01J20/3219 , B01J20/3246 , B01J20/3248 , B01J20/3272 , B01J20/3282 , B01J20/3285 , C07D498/12 , C07K14/625
Abstract: The present invention relates to a sorbent comprising a solid support material, the surface of which comprises a residue of a general formula (I), wherein the residue is attached via a covalent single bond to a functional group on the surface of either the bulk solid support material itself or of a polymer film on the surface of the solid support material. Furthermore, the present invention relates to the use of the sorbent according to the invention for the purification of organic molecules, in particular pharmaceutically active compounds, preferably in chromatographic applications
Abstract translation: 本发明涉及包含固体支持材料的吸附剂，其表面包含通式（I）的残基，其中所述残基通过共价单键连接到本体固体的表面上的官能团 支撑材料本身或固体支撑材料表面上的聚合物膜。 此外，本发明涉及根据本发明的吸附剂用于纯化有机分子，特别是药学活性化合物，优选在色谱应用中的用途
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8.发明申请SORBENT COMPRISING ON ITS SURFACE AN ALIPHATIC UNIT HAVING AN ANIONIC OR DEPROTONIZABLE GROUP FOR THE PURIFICATION OF ORGANIC MOLECULES 审中-公开包含其表面的同位素具有用于纯化有机分子的阴离子或可分解基团的脂族单元公开(公告)号：US20140343261A1
公开(公告)日：2014-11-20
申请号：US14345026
申请日：2012-09-17
Applicant: INSTRACTION GMBH
Inventor： Markus Arendt , Björn Degel , Thomas Schwarz , Gerhard Stumm , Martin Welter
IPC: B01J20/32 , C07H1/06 , C07H15/12 , B01J20/288 , C07H15/252
CPC classification number: B01J20/328 , B01J20/288 , B01J20/3219 , B01J20/3248 , B01J20/3253 , B01J20/3282 , B01J20/3285 , B01J2220/46 , B01J2220/52 , C07H1/06 , C07H15/12 , C07H15/252
Abstract: The present invention relates to a sorbent comprising a solid support material, the surface of which comprises a residue of a general formula (I), wherein the residue is attached via a covalent single bond to a functional group on the surface of either the bulk solid support material itself or of a polymer film on the surface of the solid support material. Furthermore, the present invention relates to the use of the sorbent according to the invention for the purification of organic molecules, in particular pharmaceutically active compounds, preferably in chromatographic application.
Abstract translation: 本发明涉及包含固体支持材料的吸附剂，其表面包含通式（I）的残基，其中所述残基通过共价单键连接到本体固体的表面上的官能团 支撑材料本身或固体支撑材料表面上的聚合物膜。 此外，本发明涉及根据本发明的吸着剂用于纯化有机分子，特别是药学活性化合物，优选在色谱应用中的用途。
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公开(公告)号：US20200171463A1
公开(公告)日：2020-06-04
申请号：US16735072
申请日：2020-01-06
Applicant: instrAction GmbH
Inventor： Christian Meyer , Martin Welter , Thomas Schwarz
Abstract: The present invention relates to a sorbent which is suitable for binding metals from solutions, the production of a corresponding sorbent as well as the use of the sorbent for binding metals from solutions.
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10.发明申请SORBENT COMPRISING AN AROMATIC RING SYSTEM ON ITS SURFACE FOR THE PURIFICATION OF ORGANIC MOLECULES 审中-公开在其表面上包含有机分子纯化的芳香环系统的同位素公开(公告)号：US20140243512A1
公开(公告)日：2014-08-28
申请号：US14343969
申请日：2012-09-17
Applicant: INSTRACTION GMBH
Inventor： Markus Arendt , Björn Degel , Thomas Schwarz , Gerhard Stumm , Martin Welter
IPC: B01J20/286
CPC classification number: B01J20/286 , A61K31/436 , A61K31/4745 , A61K31/7032 , B01D15/08 , B01J20/103 , B01J20/262 , B01J20/267 , B01J20/28088 , B01J20/283 , B01J20/285 , B01J20/287 , B01J20/288 , B01J20/289 , B01J20/3204 , B01J20/3219 , B01J20/3221 , B01J20/3253 , B01J20/3272 , B01J20/3282 , B01J20/3285 , C07C213/10 , C07C2601/14 , C07D491/22 , C07D498/18 , C07H17/08 , C07C215/44
Abstract: In a first embodiment the present invention relates to a sorbent comprising a porous inorganic solid support material having on its surface a film of a crosslinked polyvinylamine comprising derivatized amine groups and amine groups binding to the surface of the support material via electron donor/acceptor interactions. In a second embodiment the present invention relates to a sorbent comprising a solid support material, the surface of which comprises a residue of a general formula (I), wherein the residue is attached via a covalent single bond to a functional group on the surface of either the bulk solid support material itself or of a polymer film on the surface of the solid support material. Furthermore, the present invention relates to the use of the sorbents according to the invention for the purification of organic molecules, in particular pharmaceutical active compounds, preferably in chromatographic applications.
Abstract translation: 在第一实施方案中，本发明涉及一种吸附剂，其包含多孔无机固体支持材料，其表面上具有包含衍生的胺基团的交联聚乙烯胺的膜和通过电子给体/受体相互作用结合载体材料的表面的胺基。 在第二个实施方案中，本发明涉及包含固体支持材料的吸附剂，其表面包含通式（I）的残基，其中残基通过共价单键连接到表面上的官能团 本体固体支撑材料本身或固体支撑材料表面上的聚合物膜。 此外，本发明涉及根据本发明的吸附剂用于纯化有机分子，特别是药物活性化合物，优选在色谱应用中的用途。
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