- 专利标题: Optimized Fc variants and methods for their generation
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申请号: US14286825申请日: 2014-05-23
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公开(公告)号: US09714282B2公开(公告)日: 2017-07-25
- 发明人: Gregory Alan Lazar , Arthur J. Chirino , Wei Dang , John R. Desjarlais , Stephen K. Doberstein , Robert J. Hayes , Sher Bahadur Karki , Omid Vafa
- 申请人: Xencor, Inc.
- 申请人地址: US CA Monrovia
- 专利权人: Xencor, Inc.
- 当前专利权人: Xencor, Inc.
- 当前专利权人地址: US CA Monrovia
- 代理机构: Morgan, Lewis & Bockius, LLP
- 代理商 Robin M. Silva; Christina A. MacDougall
- 主分类号: C07K16/00
- IPC分类号: C07K16/00 ; C12P21/08 ; C07H21/02 ; C07H21/04 ; C12P21/06 ; C12P21/04 ; C12N5/00 ; C12N1/20 ; C07K16/28 ; C07K16/32 ; C07K1/00
摘要:
The present invention relates to optimized Fc variants, methods for their generation, and antibodies and Fc fusions comprising optimized Fc variants.
公开/授权文献
- US20140377256A1 OPTIMIZED FC VARIANTS AND METHODS FOR THEIR GENERATION 公开/授权日:2014-12-25
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