Invention Application
WO0158869B1 CANNABINOID RECEPTOR MODULATORS, THEIR PROCESSES OF PREPARATION, AND USE OF CANNABINOID RECEPTOR MODULATORS IN TREATING RESPIRATORY AND NON-RESPIRATORY DISEASES
审中-公开
CANNABINOID受体调节剂，其制备方法和CANNABINOID受体调节剂在治疗呼吸道疾病和非呼吸系统疾病中的应用
- Patent Title: CANNABINOID RECEPTOR MODULATORS, THEIR PROCESSES OF PREPARATION, AND USE OF CANNABINOID RECEPTOR MODULATORS IN TREATING RESPIRATORY AND NON-RESPIRATORY DISEASES
- Patent Title (中): CANNABINOID受体调节剂，其制备方法和CANNABINOID受体调节剂在治疗呼吸道疾病和非呼吸系统疾病中的应用
-
Application No.: PCT/US0104131Application Date: 2001-02-08
-
Publication No.: WO0158869B1Publication Date: 2002-02-21
- Inventor: LEFTHERIS KATERINA , ZHAO RULIN , CHEN BANG-CHI , KIENER PETER , WU HONG , PANDIT CHENNAGIRI R , WROBLESKI STEPHEN , CHEN PING , HYNES JOHN JR , LONGPHRE MALINDA , NORRIS DEREK J , SPERGEL STEVEN , TOKARSKI JOHN
- Applicant: SQUIBB BRISTOL MYERS CO , LEFTHERIS KATERINA , ZHAO RULIN , CHEN BANG CHI , KIENER PETER , WU HONG , PANDIT CHENNAGIRI R , WROBLESKI STEPHEN , CHEN PING , HYNES JOHN JR , LONGPHRE MALINDA , NORRIS DEREK J , SPERGEL STEVEN , TOKARSKI JOHN
- Assignee: SQUIBB BRISTOL MYERS CO,LEFTHERIS KATERINA,ZHAO RULIN,CHEN BANG CHI,KIENER PETER,WU HONG,PANDIT CHENNAGIRI R,WROBLESKI STEPHEN,CHEN PING,HYNES JOHN JR,LONGPHRE MALINDA,NORRIS DEREK J,SPERGEL STEVEN,TOKARSKI JOHN
- Current Assignee: SQUIBB BRISTOL MYERS CO,LEFTHERIS KATERINA,ZHAO RULIN,CHEN BANG CHI,KIENER PETER,WU HONG,PANDIT CHENNAGIRI R,WROBLESKI STEPHEN,CHEN PING,HYNES JOHN JR,LONGPHRE MALINDA,NORRIS DEREK J,SPERGEL STEVEN,TOKARSKI JOHN
- Priority: US18181800 2000-02-11
- Main IPC: A61K31/40
- IPC: A61K31/40 ; A61K31/404 ; A61K31/41 ; A61K31/415 ; A61K31/4184 ; A61K31/421 ; A61K31/422 ; A61K31/4245 ; A61K31/427 ; A61K31/428 ; A61K31/433 ; A61K31/4353 ; A61K31/438 ; A61K31/44 ; A61K31/4439 ; A61K31/454 ; A61K31/496 ; A61K31/506 ; A61K31/5377 ; A61K31/5383 ; A61K31/551 ; A61K45/00 ; A61P11/00 ; A61P11/06 ; C07D207/337 ; C07D207/40 ; C07D207/416 ; C07D209/08 ; C07D209/42 ; C07D231/14 ; C07D231/56 ; C07D233/90 ; C07D257/04 ; C07D263/32 ; C07D271/06 ; C07D401/06 ; C07D401/12 ; C07D403/06 ; C07D403/12 ; C07D405/12 ; C07D409/12 ; C07D413/12 ; C07D417/12 ; C07D453/02 ; C07D471/04 ; C07D471/08 ; C07D471/10 ; C07D498/04 ; C07D498/06 ; C07D207/34 ; C07D401/14 ; C07D407/12
Abstract:
Use of a compound for treating a respiratory disease in a mammal wherein the compound is a cannabinoid receptor modulator is disclosed. Compounds useful as cannabinoid receptor modulators for treating respiratory and non-respiratory leukocyte-activation associated diseases comprise compounds of formula (I), in which A and B are nitrogen or carbon, provided only one of A and B is nitrogen; and R1-R6 are as defined in the specification, wherein R2 with R5 may form a ring, and/or two R4 groups may form a six-membered aryl or heteroaryl ring, optionally having a substituent R6 forming a ring with R3.
Public/Granted literature
Information query
