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公开(公告)号：EP1735332B1
公开(公告)日：2011-10-19
申请号：EP05738987.6
申请日：2005-04-06
申请人： ABBOTT LABORATORIES
CPC分类号： C07J71/0042
摘要： Azacyclosteroid histamine-3 receptor ligands, pharmaceutical compositions comprising such compounds, and methods for using such compounds and compositions are described herein.
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公开(公告)号：EP1330429A2
公开(公告)日：2003-07-30
申请号：EP01989847.7
申请日：2001-10-31
申请人： Abbott Laboratories
发明人： BENNANI, Youssef, L.
IPC分类号： C07C233/49 , C07C237/22 , C07C233/09 , A61K31/16 , A61P25/00
CPC分类号： C07C237/12 , C07B2200/07 , C07C233/09
摘要： Compounds of formula (I), are novel and useful for treating seizure, migraine and psychiatric disorders.
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公开(公告)号：EP1735332A1
公开(公告)日：2006-12-27
申请号：EP05738987.6
申请日：2005-04-06
申请人： ABBOTT LABORATORIES
CPC分类号： C07J71/0042
摘要： Azacyclosteroid histamine-3 receptor ligands, pharmaceutical compositions comprising such compounds, and methods for using such compounds and compositions are described herein.
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4.发明公开CYCLOALKYLAMIDES AND THEIR THERAPEUTIC USE AS ANTIEPILEPTIC AND ANTICONVULSANT 审中-公开CYCLOALKYLAMID UND DEREN VERWENDUNG ALS ANTIEPILEPTISCHES SOWIE ANTIKONVULSIVES MITTEL
公开(公告)号：EP1606244A2
公开(公告)日：2005-12-21
申请号：EP03779179.5
申请日：2003-10-22
申请人： ABBOTT LABORATORIES
发明人： BENNANI, Youssef, L. , CHAMBERLIN, Steve, A. , CHEMBURKAR, Sanjay, R. , CHEN, Jinhua , DART, Michael, J. , GUPTA, Ashok, K. , WANG, Lei
IPC分类号： C07C233/63 , C07C233/60 , C07C233/58 , A61K31/16 , A61P25/08 , A61P25/06 , C07D233/24
CPC分类号： A61K31/16 , A61K31/33 , A61K31/397 , A61K31/54 , A61K31/55 , C07C233/08 , C07C233/58 , C07C233/60 , C07C233/63 , C07C237/22 , C07C2601/14 , C07D233/24
摘要： The present invention relates to the use of compounds of formula (I)for the treatment of a variety of disorders including, bu t not limited to, epilepsy, bipolar disorder, psychiatric disorders, migraine, pain, neuroprotection, and movement disorders.
摘要翻译： 本发明涉及式（I）化合物用于治疗各种疾病的用途，包括但不限于癫痫，双相情感障碍，精神病学障碍，偏头痛，疼痛，神经保护和运动障碍。
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5.发明公开1,3-DISUBSTITUTED AND 1,3,3-TRISUBSTITUTED PYRROLIDINES AS HISTAMINE-3 RECEPTOR LIGANDS AND THEIR THERAPEUTIC APPLICATIONS 有权1.3二取代和1,3,3-三 - 取代的吡咯烷作为组胺-3受体和治疗用途配体
公开(公告)号：EP1301480A1
公开(公告)日：2003-04-16
申请号：EP01952653.2
申请日：2001-07-11
申请人： ABBOTT LABORATORIES
发明人： BENNANI, Youssef, L. , FAGHIH, Ramin , DWIGHT, Wesley, J. , VASUDEVAN, Anil , CONNER, Scott, E.
IPC分类号： C07D207/12 , C07D207/14 , C07D207/16 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D409/12 , C07D417/12 , C07D403/04 , C07D417/14 , A61K31/4025 , A61P9/10 , A61P25/28 , A61P29/00
CPC分类号： C07D401/12 , C07D207/12 , C07D207/14 , C07D207/16 , C07D401/14 , C07D403/04 , C07D403/12 , C07D405/12 , C07D409/12 , C07D417/12 , C07D417/14
摘要： Compounds of formula (I) are useful in treating diseases or conditions prevented by or ameliorated with histamine-3 receptor ligands. Also disclosed are histamine-3 receptor ligand compositions and methods of antagonizing or agonizing histamine-3 receptors.
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6.发明授权FUSED CYCLOALKYL AMIDES AND ACIDS AND THEIR THERAPEUTIC APPLICATIONS FOR THE TREATMENT OF I.A. EPILEPSY 有权稠合环烷基酰胺和羧酸衍生物及其用于治疗U.A.的治疗 癫痫
公开(公告)号：EP1562575B1
公开(公告)日：2009-05-20
申请号：EP03777773.7
申请日：2003-10-22
申请人： ABBOTT LABORATORIES
发明人： BENNANI, Youssef, L. , CHANG, Sou-Jen , CHEMBURKAR, Sanjay, R. , DART, Michael, J. , FERNANADO, Dilinie, P. , GRIEME, Timothy, A.
IPC分类号： A61K31/19 , A61P25/08 , C07C61/135 , C07C69/753 , C07C233/58 , C07C237/24 , C07C61/13
CPC分类号： A61K31/55 , A61K31/33 , A61K31/397 , A61K31/401 , A61K31/495 , A61K31/537 , A61K31/54 , C07C61/13 , C07C61/135 , C07C61/29 , C07C69/753 , C07C233/58 , C07C237/22 , C07C2602/18 , C07C2602/20 , C07C2602/22 , C07C2602/24 , C07C2603/08 , C07C2603/12 , C07C2603/62 , C07C2603/66
摘要： The present invention relates to the use of compounds of formula (I) for the treatment of epilepsy, bipolar disorder, psychiatric disorders, migraine, pain, or movement disorders, and to provide neuroprotection.
摘要翻译： 本发明涉及使用式（I），用于癫痫，双相性精神障碍，精神障碍，偏头痛，疼痛，或运动障碍的治疗中的化合物，并提供神经保护。
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公开(公告)号：EP1558230B1
公开(公告)日：2008-12-31
申请号：EP03774943.9
申请日：2003-10-22
申请人： ABBOTT LABORATORIES
发明人： BENNANI, Youssef, L. , BUNNELLE, William, H. , CHANG, Sou-Jen , CHEMBURKAR, Sanjay, R. , CHEN, Jinhua , DART, Michael, J. , FERNANADO, Dilinie, P. , KU, Yi-Yin , LOCKWOOD, Mark , WANG, Lei
IPC分类号： A61K31/16 , A61K31/19 , C07C233/00 , C07C229/00 , C07C61/00 , A61P25/00 , A61P29/00
CPC分类号： C07C69/753 , C07C61/13 , C07C61/135 , C07C233/58 , C07C233/60 , C07C233/63 , C07C2601/02 , C07C2601/14 , C07C2601/18 , C07C2602/10 , C07C2602/20 , C07C2602/42 , C07C2603/95
摘要： The present invention relates to the use of compounds of Formula (I) for the treatment of epilepsy, bipolar disorder, psychiatric disorders, migraine, pain, or movement disorders, and to provide neuroprotection.
摘要翻译： 本发明涉及式（I）化合物用于治疗癫痫，双相情感障碍，精神障碍，偏头痛，疼痛或运动障碍的用途，并提供神经保护作用。
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公开(公告)号：EP1474132A1
公开(公告)日：2004-11-10
申请号：EP03729628.2
申请日：2003-01-10
申请人： Abbott Laboratories
发明人： HANCOCK, Arthur, A. , BUSH, Eugene, N. , COWART, Marlon, D. , JACOBSON, Peer, B. , OPGENORTH, Terry, J. , BENNANI, Youssef, L.
IPC分类号： A61K31/4025 , A61P3/10 , A61P3/00
CPC分类号： A61K31/40 , A61K31/00 , A61K31/165 , A61K31/353 , A61K31/382 , A61K31/397 , A61K31/4025 , A61K31/454 , A61K31/496 , A61K31/5377 , A61K31/541 , A61K31/55
摘要： The invention relates to a method of treating a diabetic condition by administering a therapeutically effective amount of a histamine-3 receptor antagonist, including benzofuran and benzopyran derivatives of formula (I), aminoalkoxybiphenylcarboxamide compounds of formula (III), and aminoetherbiphenyl compounds of formula (IV) as described herein.
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9.发明授权1,3-DISUBSTITUTED AND 1,3,3-TRISUBSTITUTED PYRROLIDINES AS HISTAMINE-3 RECEPTOR LIGANDS AND THEIR THERAPEUTIC APPLICATIONS 有权1.3二取代和1,3,3-三 - 取代的吡咯烷作为组胺-3受体和治疗用途配体
公开(公告)号：EP1301480B1
公开(公告)日：2007-09-12
申请号：EP01952653.2
申请日：2001-07-11
申请人： ABBOTT LABORATORIES
发明人： BENNANI, Youssef, L. , FAGHIH, Ramin , DWIGHT, Wesley, J. , VASUDEVAN, Anil , CONNER, Scott, E.
IPC分类号： C07D207/12 , C07D207/14 , C07D207/16 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D409/12 , C07D417/12 , C07D403/04 , C07D417/14 , A61K31/4025 , A61P9/10 , A61P25/28 , A61P29/00
CPC分类号： C07D401/12 , C07D207/12 , C07D207/14 , C07D207/16 , C07D401/14 , C07D403/04 , C07D403/12 , C07D405/12 , C07D409/12 , C07D417/12 , C07D417/14
摘要： Compounds of formula (I) are useful in treating diseases or conditions prevented by or ameliorated with histamine-3 receptor ligands. Also disclosed are histamine-3 receptor ligand compositions and methods of antagonizing or agonizing histamine-3 receptors.
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公开(公告)号：EP1569637A1
公开(公告)日：2005-09-07
申请号：EP03768721.7
申请日：2003-11-05
申请人： ABBOTT LABORATORIES
发明人： ALTENBACH, Robert, J. , BLACK, Lawrence, A. , CHANG, Sou-Jen , COWART, Marlon, D. , FAGHIH, Ramin , GFESSER, Gregory, A.; , KU, Yi-Yin , LIU, Huaqing , LUKIN, Kirill, A. , NERSESIAN, Diana, L. , PU, Yu-ming , SHARMA, Padam, N. , BENNANI, Youssef, L. , CURTIS, Michael, P.
IPC分类号： A61K31/40 , C07D295/155 , C07D295/116 , A61P25/00 , A61P3/00 , C07D261/08 , C07D207/08 , C07D207/12 , C07D207/14 , C07C255/58 , C07D295/088 , C07D207/20 , C07D215/12 , C07D215/14 , C07D217/14
CPC分类号： C07C255/58 , C07D207/08 , C07D207/12 , C07D207/14 , C07D207/20 , C07D213/30 , C07D213/38 , C07D213/61 , C07D213/64 , C07D213/85 , C07D215/12 , C07D215/14 , C07D215/20 , C07D217/14 , C07D237/12 , C07D237/14 , C07D237/28 , C07D239/26 , C07D239/28 , C07D239/42 , C07D239/52 , C07D241/12 , C07D241/42 , C07D263/32 , C07D277/28 , C07D295/073 , C07D295/088 , C07D295/096 , C07D295/112 , C07D295/135 , C07D295/155 , C07D401/04 , C07D401/10 , C07D403/04 , C07D403/10 , C07D405/04 , C07D409/04 , C07D413/04 , C07D417/04 , C07D471/04
摘要： Compounds of formula (I) are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions comprising the histamine-3 receptor ligands, methods for using such compounds and compositions, and a process for preparing compounds within the scope of formula (I).
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