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公开(公告)号：EP1051419A4
公开(公告)日：2002-08-28
申请号：EP98963113
申请日：1998-12-11
IPC分类号： C07D223/08 , A61K31/554 , A61P9/04 , A61P9/12 , C07D223/12 , C07D513/04
CPC分类号： C07D513/04 , C07D223/12
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2.发明公开PREPARATION OF (S)-2-AMINO-6,6-DIMETHOXYHEXANOIC ACID METHYL ESTER VIA NOVEL DIOXOLANES 审中-公开HERSTELLUNG VON（S）-2-氨基-6,6-二甲氧基雄甾烷-G-甲酯通过NEUARTIGER二氧戊环
公开(公告)号：EP1121351A4
公开(公告)日：2003-05-02
申请号：EP99932163
申请日：1999-07-01
发明人： GODFREY JOLLIE D JR , KRONENTHAL DAVID R , SCHWINDEN MARK D , SRIVASTAVA SUSHIL K , RAMIG KEITH , VENIT JOHN J , JASS PAUL A , RACHA SAIBABA , DILLON JOHN L JR , SOUNDARARAJAN NACHIMUTHU , POWERS GERALD L , KOTNIS ATUL S
IPC分类号： A61K31/554 , A61P9/04 , A61P9/12 , A61P43/00 , C07C229/22 , C07D317/30 , C07D513/04 , C07D317/26 , C07D317/28
CPC分类号： C07C229/22 , C07D317/30
摘要： The invention relates to the synthesis of 2-amino-6, 6-dimethoxy hexanoic acid, methyl ester and novel dioxalane intermediates thereof, from the reaction of glycinamide of formula I with dioxolane of formula II.
摘要翻译： 本发明涉及由式I的甘氨酰胺与式II的二氧戊环反应合成2-氨基-6,6-二甲氧基己酸，甲酯和其新二氧杂环戊烷中间体。
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公开(公告)号：EP1089973A4
公开(公告)日：2001-12-12
申请号：EP99930402
申请日：1999-06-18
发明人： BISACCHI GREGORY , SLUSARCHYK WILLIAM A , TREUNER UWE , SUTTON JAMES C , ZAHLER ROBERT , SEILER STEVEN , KRONENTHAL DAVID R , RANDAZZO MICHAEL E , XU ZHONGMIN , SHI ZHONGPING , SCHWINDEN MARK D
IPC分类号： A61K31/195 , A61K31/397 , A61K31/4025 , A61K31/4427 , A61K31/4433 , A61K31/4523 , A61K31/4725 , A61K31/496 , A61K31/506 , A61K31/551 , A61P11/00 , A61P11/02 , A61P11/06 , A61P29/00 , A61P43/00 , C07D205/08 , C07D205/09 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/06 , C07D403/12 , C07D409/06 , A61K31/395
CPC分类号： C07D403/12 , C07D205/08
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公开(公告)号：EP1644384A4
公开(公告)日：2009-09-02
申请号：EP03812974
申请日：2003-12-10
发明人： PENDRI YADAGIRI R , CHEN CHUNG-PIN H , PATEL SUNIL S , EVANS JEFFREY M , LIANG JING , KRONENTHAL DAVID R , POWERS GERALD L , PRASAD SIVA JOSYULA , BIEN JEFFREY T , SHI ZHONGPING , PATEL RAMESH N , CHAN YEUNG Y , RIJHWANI SUSHIL K , SINGH AMBARISH K , WANG SHAOPENG , STOJANOVIC MILAN , POLNIASZEK RICHARD , LEWIS CHARLES , THOTTATHIL JOHN , KRISHNAMURTY DHILEEPKUMAR
IPC分类号： C07D473/18 , C07D473/12 , C07F7/08 , C07F7/18
CPC分类号： C07F7/1856 , C07D473/18 , C07F7/0812 , C07F7/0814 , C07F7/0818 , C07F7/0827 , C07F7/083
摘要： Processes are disclosed for preparing the antiviral agent entecavir. A resin adsorption process for the isolation and purification of entecavir is also disclosed. Various intermediates useful in the preparation of entecavir are also disclosed.
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5.发明公开PROCESS FOR THE PREPARATION OF 3,7-DISUBSTITUTED-2,3,4,5- TETRAHYDRO-1H-1,4-BENZODIAZEPINE COMPOUNDS 审中-公开用于生产3,7-二取代的2,3,4,5-四氢-1H-1,4-苯并二氮杂化合物
公开(公告)号：EP1443936A4
公开(公告)日：2006-01-11
申请号：EP02793948
申请日：2002-11-12
IPC分类号： A61P35/00 , C07C255/58 , C07C255/61 , C07D233/54 , C07D233/66 , C07D233/88 , C07D233/90 , C07D243/14 , C07D333/34 , C07D403/06 , C07D409/12 , C07D409/14 , C07F7/18 , A61K31/55 , C07C255/00 , C07D333/32 , C07F7/04 , C07F7/10
CPC分类号： C07D233/64 , C07C255/58 , C07C255/61 , C07D243/14 , C07D333/34 , C07D403/06 , C07D409/12 , C07D409/14 , C07F7/1852
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