专利检索 ipc:"C07H1/04" 第 1 页

1.

发明授权
A METHOD OF INHIBITING ISOMERIZATION OF A REDUCING SACCHARIDE UPON THERMAL TREATMENT 有权

公开(公告)号：EP3375291B1

公开(公告)日：2022-08-10

申请号：EP17161671.7

申请日：2017-03-17

发明人： Wartenberg, Dr. Dirk

IPC分类号： C12P19/00 , C12P19/18 , C12P19/26 , A23L33/21 , A23C7/04 , A23C9/154 , A23C9/15 , A23C9/20 , C07H1/08 , C07H1/04 , C07H3/06 , A23C9/156 , A61K31/7016 , C07H3/04 , C13B50/00 , C13K5/00 , C13K7/00 , C13K13/00 , A23L29/30 , A23L33/00

2.

发明公开
METHOD FOR PREPARING 3'-O-AMINO-2'-DEOXYRIBONUCLEOSIDE-5'-TRIPHOSPHATE 审中-公开

公开(公告)号：EP3844167A1

公开(公告)日：2021-07-07

申请号：EP19758988.0

申请日：2019-08-29

申请人： DNA Script , Institut Pasteur

发明人： SARAC, Ivo , HOLLENSTEIN, Marcel

IPC分类号： C07H1/00 , C07H1/04 , C07H21/04

3.

发明公开
METHODS OF PREPARING SUBSTITUTED NUCLEOTIDE ANALOGS 审中-公开

公开(公告)号：EP3160979A4

公开(公告)日：2018-01-03

申请号：EP15812727

申请日：2015-06-22

申请人： ALIOS BIOPHARMA INC

发明人： SEREBRYANY VLADIMIR , BEIGELMAN LEONID

IPC分类号： C07H1/04 , C07H19/067 , C07H19/10

CPC分类号： C07H1/02 , C07H1/00 , C07H19/10 , C07H23/00

摘要： Disclosed herein are methods of preparing a phosphoroamidate nucleotide analog, which are useful in treating diseases and/or conditions such as viral infections.

4.

发明公开
SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF 审中-公开

公开(公告)号：EP3055319A4

公开(公告)日：2018-01-10

申请号：EP14851776

申请日：2014-10-09

申请人： ALIOS BIOPHARMA INC

发明人： BEIGELMAN LEONID , WANG GUANGYI , SMITH DAVID BERNARD , PRHAVC MARIJA , JEKLE CHRISTIAN ANDREAS , DEVAL JEROME

IPC分类号： C07H19/06 , A61K31/14 , A61K31/16 , A61K31/7068 , A61K31/7072 , A61K31/7076 , A61K31/708 , A61P31/14 , A61P31/16 , C07H1/00 , C07H1/02 , C07H1/04 , C07H19/10 , C07H19/11 , C07H19/16 , C07H19/167 , C07H19/173 , C07H19/20 , C07H19/207 , C07H19/213

CPC分类号： C07H19/20 , A61K31/7052 , A61K31/7064 , A61K31/7072 , A61K31/7076 , A61K31/708 , C07H19/06 , C07H19/10 , C07H19/11 , C07H19/16 , C07H19/207 , C07H19/213

摘要： Disclosed herein are nucleosides, nucleotides and nucleotide analogs, methods of synthesizing the same and methods of treating diseases and/or conditions such as a Picornavirus and/or Flaviviridae infection with one or more nucleosides, nucleotides and nucleotide analogs.

5.

发明公开
PURIFICATION OF TRIPHOSPHORYLATED OLIGONUCLEOTIDES USING CAPTURE TAGS AND MODIFIED TRIPHOSPHORYLATED OLIGONUCLEOTIDES AS ACTIVATORS OF RIG-1 HELICASE 审中-公开
标题翻译：用捕获标记和修饰的三磷酸化寡核苷酸作为RIG-1激酶的激活剂纯化三磷酸化寡核苷酸

公开(公告)号：EP3199538A1

公开(公告)日：2017-08-02

申请号：EP17161309.4

申请日：2012-03-28

申请人： Rheinische Friedrich-Wilhelms-Universität Bonn

发明人： Ludwig, Janos , Goldeck, Marion, , Sproat,Brian,

IPC分类号： C07H21/02 , C07H1/04

摘要： The present invention relates to a method of preparing triphosphate-modified oligonucleotides using a capture tag. The method allows the synthesis and purification of triphosphate-modified oligonucleotides in high yield and purity suitable for pharmaceutical applications.

摘要翻译： 本发明涉及使用捕获标签制备三磷酸盐修饰的寡核苷酸的方法。该方法允许合成和纯化适用于药物应用的高产率和纯度的三磷酸酯修饰的寡核苷酸。

6.

发明授权
METHOD FOR PRODUCING P1,P4-DI(URIDINE 5'-)TETRAPHOSPHATE 有权
标题翻译：生产P1，P4-DI（尿嘧啶5' - ）四磷酸酯的方法

公开(公告)号：EP2940030B1

公开(公告)日：2017-06-14

申请号：EP13869663.8

申请日：2013-12-10

申请人： YAMASA CORPORATION

发明人： YAMADA, Kohei

IPC分类号： C07H19/10 , C07H1/04 , C07H21/00

CPC分类号： C07H19/10 , A61K31/7072 , A61K31/7105 , C07F9/65586

7.

发明公开
CELLULOSE PHOSPHATE POWDER PRODUCT AND PROCESS FOR MANUFACTURE THEREOF, AND APPLICATION TO REMOVAL OF CONTAMINANTS FROM AQUEOUS SOLUTIONS 审中-公开
标题翻译：磷酸纤维素粉末产品AND METHOD FOR FOR从水溶液中污染的去除生产和应用

公开(公告)号：EP2670711A4

公开(公告)日：2017-03-29

申请号：EP12742299

申请日：2012-02-01

申请人： AUSTRALIAN BIOREFINING PTY LTD

发明人： BLUNN ADAM JUSTIN

IPC分类号： C02F1/28 , B01D39/00 , B01J20/22 , B01J20/24 , B01J20/30 , C02F101/10 , C02F101/20 , C02F101/22 , C07H1/02 , C07H1/04 , C08B5/00 , C08H8/00 , C08J3/14 , C08L1/16

CPC分类号： B01J20/24 , B01J20/3085 , B01J2220/4825 , B01J2220/4831 , C02F1/286 , C02F2101/103 , C02F2101/106 , C02F2101/20 , C02F2101/206 , C02F2101/22 , C08B5/00 , C08H8/00 , C08J3/14 , C08J2301/16 , C08L1/16

8.

发明公开
USE OF XYLENE MONOOXYGENASE FOR THE OXIDATION OF SUBSTITUTED MONOCYCLIC AROMATIC COMPOUNDS 审中-公开
标题翻译：二甲苯单加氧酶氧化取代的环芳烃MONO的使用

公开(公告)号：EP1485470A2

公开(公告)日：2004-12-15

申请号：EP02757381.5

申请日：2002-08-09

申请人： E.I. DU PONT DE NEMOURS AND COMPANY

发明人： BRAMUCCI, Michael, G. , NAGARAJAN, Vasantha , THOMAS, Stuart, M.

IPC分类号： C12N9/04 , C12N5/00 , C12N15/00 , C12N1/00 , C12N1/20 , C07H1/04

CPC分类号： C12N9/0071 , C12P7/42

摘要： The invention relates to a biocatalytic process for the oxidation of substituted monocyclic aromatic compounds to the corresponding carboxylic acids and related compounds. In a preferred embodiment the invention describes a biocatalytic process to produce 4-hydroxymethylbenzoic acid and 3-hydroxymethylbenzoic acid from p-xylene and m-xylene, respectively. 4-hydroxymethylbenzoic acid has been prepared by oxidizing p-xylene with a single recombinant microorganism containing the enzyme xylene monooxygenase.

9.

发明授权
NEW METHOD OF POLYPHOSPHATE SYNTHESIS 有权

公开(公告)号：EP2880044B1

公开(公告)日：2019-11-27

申请号：EP13750163.1

申请日：2013-07-29

申请人： Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

发明人： CHMIELEWSKI, Marcin Krzysztof , ROMANOWSKA, Joanna

IPC分类号： C07H1/04 , C07H19/10

10.

发明公开
METHODS FOR THE PREPARATION OF DIASTEREOMERICALLY PURE PHOSPHORAMIDATE PRODRUGS 审中-公开
标题翻译：用于制备经济上纯的磷酰胺酸前体的方法

公开(公告)号：EP3194414A1

公开(公告)日：2017-07-26

申请号：EP15763562.4

申请日：2015-09-11

申请人： MEDIVIR AB

发明人： PINHO, Pedro , TORSSELL, Staffan

IPC分类号： C07H1/04 , C07H19/10 , C07H19/20

CPC分类号： C07H1/02 , C07H1/04 , C07H19/10 , C07H19/20

摘要： Methods for the preparation of diastereomerically pure phosphoramidate prodrugs of nucleosides, and intermediates useful for the preparation are provided. The nucleosides are useful for the treatment of hepatitis C and cancer.

摘要翻译： 提供了用于制备核苷的非对映异构纯氨基磷酸酯前药的方法，以及用于制备的中间体。核苷可用于治疗丙型肝炎和癌症。