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891 条记录 (耗时 0.02 秒)

    PURIFICATION OF N,N-DIMETHYLACETAMIDE
    92.
    发明公开
    PURIFICATION OF N,N-DIMETHYLACETAMIDE 有权
    N，N-二甲基乙酰胺的纯化

    公开(公告)号：EP1551522A4

    公开(公告)日：2005-10-19

    申请号：EP03737193

    申请日：2003-06-18

    申请人： MALLINCKRODT INC

    发明人： GENTILCORE MICHAEL J

    IPC分类号： B01D3/14 ,  B01D3/42 ,  C07C231/24 ,  C07C233/05 ,  C07C233/00

    CPC分类号： C07C231/24 ,  B01D3/146 ,  Y10S203/09 ,  C07C233/05

    摘要： A method to purify N,N-dimethylacetamide (DMAc) from an aqueous solution containing acetic acid as a contaminant. Two fractional distillation columns (10, 20) are arranged in series. The first column (10) has a condenser (11) overhead and a reboiler (13) at the bottom. The second column (20) also has a condenser (21) overhead and a reboiler (23) at the bottom. The solution containing the contaminant is provided to the first column (10) with a temperature profile to result in acetic acid partitioning into the overhead water. The material remaining in the bottom portion of the first column is recycled to the first column and also provided in a second column (20), whereby DMAc free of acetic acid contamination is recovered, and remaining DMAc and acetic acid are returned to the first column for further separation.

    METHOD FOR PREVENTING FLUORESCENCE QUENCHING
    95.
    发明授权
    METHOD FOR PREVENTING FLUORESCENCE QUENCHING 有权
    预防荧光淬火的方法

    公开(公告)号：EP1250093B1

    公开(公告)日：2005-03-30

    申请号：EP01904884.2

    申请日：2001-01-17

    申请人： MALLINCKRODT INC.

    发明人： ACHILEFU, Samuel, I. ,  RAJAGOPALAN, Raghavan ,  DORSHOW, Richard, B. ,  BUGAJ, Joseph, E.

    IPC分类号： A61B10/00 ,  A61K41/00

    CPC分类号： A61K49/0056 ,  A61K41/0033 ,  A61K41/0057 ,  A61K49/0032

    摘要： The sensitivity and specificity of the optical modality can be enhanced by the use of highly absorbing dyes as contrast agents. Novel indocyanine dyes that absorb and emit light in the near infrared region of electromagnetic spectrum are disclosed. These dyes are useful for imaging, diagnosis and therapy of various diseased states. Particularly, the molecules of the invention are useful for optical diagnostic imaging and therapy, in endoscopic applications for the detection of tumors and other abnormalities, for localized therapy, for photoacoustic tumor imaging, detection and therapy, and for sonofluorescence tumor imaging, detection and therapy.

    摘要翻译： 光学模式的灵敏度和特异性可以通过使用高吸收染料作为造影剂来增强。 公开了在电磁光谱的近红外区域吸收和发射光的新型吲哚菁染料。 这些染料可用于各种疾病状态的成像，诊断和治疗。 特别地，本发明的分子可用于光学诊断成像和治疗，用于检测肿瘤和其他异常的内窥镜应用，局部治疗，光声肿瘤成像，检测和治疗，以及声荧光肿瘤成像，检测和治疗 。

    METHOD FOR PREVENTING FLUORESCENCE QUENCHING
    96.
    发明授权
    METHOD FOR PREVENTING FLUORESCENCE QUENCHING 有权
    程序，以防止荧光灭绝

    公开(公告)号：EP1250092B1

    公开(公告)日：2005-03-30

    申请号：EP01904883.4

    申请日：2001-01-17

    申请人： MALLINCKRODT INC.

    发明人： ACHILEFU, Samuel, I. ,  RAJAGOPALAN, Raghavan ,  DORSHOW, Richard, B. ,  BUGAJ, Joseph, E.

    IPC分类号： A61B10/00 ,  A61K41/00

    CPC分类号： A61K49/0032 ,  A61K41/0033 ,  A61K41/0057 ,  A61K49/0056

    摘要： The sensitivity and specificity of the optical modality can be enhanced by the use of highly absorbing dyes as contrast agents. Novel cyanine dyes that absorb and emit light in the near infrared region of electromagnetic spectrum are disclosed. These dyes are useful for imaging, diagnosis and therapy of various diseased states. Particularly, the molecules of the invention are useful for optical diagnostic imaging and therapy, in endoscopic applications for the detection of tumors and other abnormalities, for localized therapy, for photoacoustic tumor imaging, detection and therapy, and for sonofluorescence tumor imaging, detection and therapy.

    PLIABLE RESPIRATORY MASK
    99.
    发明授权
    PLIABLE RESPIRATORY MASK 有权
    FALTBARE BEATMUNGSMASKE

    公开(公告)号：EP1191967B1

    公开(公告)日：2004-12-29

    申请号：EP00937732.6

    申请日：2000-05-25

    申请人： MALLINCKRODT INC.

    发明人： HANSEN, Gary, L. ,  BLOOM, Nicole, Denise

    IPC分类号： A61M16/06 ,  A62B18/08

    CPC分类号： A61M16/06 ,  A61M16/0683 ,  A61M2205/0216 ,  A61M2205/0238 ,  A61M2210/0618

    摘要： A pliable respiratory mask (100) is provided according to the invention. The pliable respiratory mask (100) includes a mask shell (104) adapted to fit over a portion of a face of a person, the mask shell (104) being formed of a pliable material selected from the group consisting of a woven fabric, a non-woven fabric, a non-woven paper, or a pliable foam material, a hose connector (112) extending through the pliable material of the mask shell (104) and fastened to the pliable material, and an attachment (109) for securing the shell (104) over a portion of the person's face.

    摘要翻译： 根据本发明提供了一种柔韧的呼吸面罩。 柔性呼吸面罩包括适于装配在人的脸部的一部分上的面罩壳，面罩壳由柔韧材料形成，该柔韧材料选自织造织物，无纺织物，无纺布 纸或柔性泡沫材料，软管连接器，其延伸穿过面罩壳的柔韧材料并且紧固到柔韧材料，以及用于将壳固定在人脸部分上的附件。