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91.发明公开
公开(公告)号：EP3201335A1
公开(公告)日：2017-08-09
申请号：EP15779025.4
申请日：2015-10-02
IPC分类号： C12N9/26
CPC分类号： C12N9/2431 , A23L27/33 , A23L33/125 , A23V2002/00 , C12P19/16 , C12Y302/01026
摘要： The invention provides variants of the Aspergillus japonicus β-fructofuranosidase enzyme which have been modified so as to improve synthesis of inulin-type fructooligosaccharides (FOS) from sucrose. One or more substitutions may be made to the parent β-fructofuranosidase polypeptide at amino acid positions 121, 159, 302 and/or 471 of the mature peptide (SEQ ID NO: 3), corresponding to crystal positions 140, 178, 321 and 490. A method of synthesizing FOS using the variants is also claimed.
摘要翻译： 本发明提供了已被修饰以改善由蔗糖合成菊糖型低聚果糖（FOS）的日本曲霉β-呋喃果糖苷酶的变体。 可以在成熟肽（SEQ ID NO：3）的氨基酸位置（121,159,302和/或471）处对亲本β-呋喃果糖苷酶多肽进行一个或多个取代，其对应于结晶位置（140,178， 321和490）。 要求保护使用这些变体合成FOS的方法。
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公开(公告)号：EP3197471A1
公开(公告)日：2017-08-02
申请号：EP15791360.9
申请日：2015-09-25
CPC分类号： A61K36/77 , A61K9/0053 , A61K39/0011 , A61K45/06 , A61K2039/585 , A61P35/00
摘要： The invention disclosed herein relates to the use of an extract of Dodonaea viscosa in breast cancer therapy, either alone or in combination with other breast cancer therapies.
摘要翻译： 本文公开的发明涉及粘多糖（Dodonaea viscosa）的提取物单独或与其他乳腺癌疗法组合在乳腺癌治疗中的用途。
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93.发明公开YEAST EXPRESSING SACCHAROLYTIC ENZYMES FOR CONSOLIDATED BIOPROCESSING USING STARCH AND CELLULOSE 审中-公开酵母表达淀粉和纤维素用于固结生物加工的糖化酶
公开(公告)号：EP3168300A1
公开(公告)日：2017-05-17
申请号：EP16192843.7
申请日：2011-06-03
发明人： BREVNOVA, Elena , MCBRIDE, John, E. , WISWALL, Erin , WENGER, Kevin, S. , CAIAZZA, Nicky , HAU, Heidi, H. , ARGYROS, Aaron , AGBOGBO, Frank , RICE, Charles, F. , BARRETT, Trisha , BARDSLEY, John, S. , FOSTER, Abigail, S. , WARNER, Anne, K. , MELLON, Mark , SKINNER, Ryan , SHIKHARE, Indraneel , DEN HAAN, Riaan , GANDHI, Chhayal, V. , BELCHER, Alan , RAJGARHIA, Vineet, B. , FROEHLICH, Allan, C. , DELEAULT, Kristen, M. , STONEHOUSE, Emily , TRIPATHI, Shital, A. , GOSSELIN, Jennifer , CHIU, Yin-Ying , XU, Haowen
CPC分类号： C12N15/52 , C12N9/2405 , C12N9/2437 , C12N9/2445 , C12N9/248 , C12N9/2482 , C12N15/81 , C12P7/06 , C12Y302/01004 , C12Y302/01008 , C12Y302/01021 , C12Y302/01091 , Y02E50/17
摘要： The present invention is directed to a yeast strain, or strains, secreting a full suite, or any subset of that full suite, of enzymes to hydrolyze corn starch, corn fiber, lignocellulose, (including enzymes that hydrolyze linkages in cellulose, hemicellulose, and between lignin and carbohydrates) and to utilize pentose sugars (xylose and arabinose). The invention is also directed to the set of proteins that are well expressed in yeast for each category of enzymatic activity. The resulting strain, or strains can be used to hydrolyze starch and cellulose simultaneously. The resulting strain, or strains can be also metabolically engineered to produce less glycerol and uptake acetate. The resulting strain, or strains can also be used to produce ethanol from granular starch without liquefaction. The resulting strain, or strains, can be further used to reduce the amount of external enzyme needed to hydrolyze a biomass feedstock during an Simultaneous Saccharification and Fermentation (SSF) process, or to increase the yield of ethanol during SSF at current saccharolytic enzyme loadings. In addition, multiple enzymes of the present invention can be co-expressed in cells of the invention to provide synergistic digestive action on biomass feedstock. In some aspects, host cells expressing different heterologous saccharolytic enzymes can also be co-cultured togetherand used to produce ethanol from biomass feedstock.
摘要翻译： 本发明涉及一种或多种酵母菌株，其分泌全套或全套的任何子集的酶以水解玉米淀粉，玉米纤维，木质纤维素（包括水解纤维素，半纤维素和 在木质素和碳水化合物之间）并利用戊糖（木糖和阿拉伯糖）。 本发明还涉及用于每种酶活性类别的在酵母中良好表达的一组蛋白质。 所得菌株或菌株可用于同时水解淀粉和纤维素。 得到的菌株或菌株也可以被代谢工程化以产生更少的甘油并摄取乙酸盐。 所得到的菌株或菌株也可用于从粒状淀粉生产乙醇而不液化。 得到的一种或多种菌株可以进一步用于减少在同时糖化和发酵（SSF）过程中水解生物质原料所需的外部酶的量，或者在当前的糖分解酶载量下在SSF期间增加乙醇的产量。 另外，本发明的多种酶可以在本发明的细胞中共表达以提供对生物质原料的协同消化作用。 在一些方面，表达不同异源糖分解酶的宿主细胞也可以共培养以用于从生物质原料生产乙醇。
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公开(公告)号：EP2601115B1
公开(公告)日：2016-11-23
申请号：EP11814168.8
申请日：2011-08-04
CPC分类号： B65D88/745 , F25D17/06 , F25D2317/0655 , F25D2317/0661
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公开(公告)号：EP3078923A1
公开(公告)日：2016-10-12
申请号：EP16164001.6
申请日：2016-04-06
IPC分类号： F24J2/52
CPC分类号： F16M11/24 , F16B7/0493 , F16B7/18 , F24S25/00 , F24S25/12 , F24S25/13 , F24S25/16 , F24S25/30 , F24S25/65 , F24S25/67 , F24S25/70 , F24S2025/80 , H02S20/30 , Y02E10/47
摘要： A height adjustable pylon (2, 15) and supporting frame assembly (1) is provided. The frame includes two frame members (3) meeting at a corner with the frame members being generally co-planar and the pylon (2, 15) being urged into the corner so as to extend at generally right angles to a plane including the two frame members. A fastener assembly has two end portions (23) each anchored relative its associated frame member so as to extend transversely to it. The fastener assembly (21) includes an intermediate saddle portion (22) engaging a surface of the pylon (2) that is directed outwardly relative to the corner with the pylon being urged into the corner when the fastener assembly is tightened to engage the pylon and lock it axially relative to the frame members (3) in a selected position. Preferably, the frame members each form two upper and two lower frame members of two trusses. Lower ends of the pylons may support the assembly.
摘要翻译： 提供高度可调的吊架（2,15）和支撑框架组件（1）。 框架包括两个框架构件（3），该框架构件（3）在一个角处相接，框架构件大体上是共面的，并且塔架（2,15）被推动到角落中，以便与包括两个框架的平面大致成直角地延伸 成员。 紧固件组件具有两个端部（23），每个端部相对于其相关联的框架构件锚固以便横向延伸。 紧固件组件（21）包括中间鞍形部分（22），该中间鞍座部分（22）接合塔架（2）的表面，该表面相对于拐角向外指向，当紧固件组件被紧固以接合塔架时，塔架被推入拐角 在选定位置相对于框架构件（3）将其轴向锁定。 优选地，框架构件各自形成两个桁架的两个上部框架构件和两个下部框架构件。 塔的下端可以支撑组件。
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公开(公告)号：EP2917658A1
公开(公告)日：2015-09-16
申请号：EP13802715.6
申请日：2013-11-06
发明人： MALAN, Karel, Johan , GAUCHÉ, Paul
IPC分类号： F24J2/52
CPC分类号： F24S25/30 , F24S20/20 , F24S23/77 , F24S25/10 , F24S25/16 , F24S25/70 , F24S2023/87 , Y02E10/47
摘要： A support structure (10) for carrying a plurality of heliostats (12) is provided. The support structure (10) includes a frame (20) formed from a number of girders (22). The frame has a triangular outer perimeter and a plurality of mountings (26) for carrying the heliostats (12) are provided along the perimeter. At least one mounting (26) is provided at or near each vertex (16) of the triangular outer perimeter of the frame (20), and at least one additional mounting (26) is provided part-way along each side (17) of the triangular outer perimeter of the frame (20).
摘要翻译： 提供了用于承载多个定日镜（12）的支撑结构（10）。 支撑结构（10）包括由多个桁材（22）形成的框架（20）。 框架具有三角形外周边，并且沿着周边设置有用于承载定日镜（12）的多个安装件（26）。 至少一个安装件（26）设置在框架（20）的三角形外周边的每个顶点（16）处或附近，并且至少一个附加安装件（26）沿着每个侧面（17）分开设置 框架（20）的三角形外周边。
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97.发明公开A FURANONE CONTAINING POLYMER COMPOUND WITH BACTERIA-ADHESION PROPERTIES 有权富良野含BAKTERIENANHAFTUNGSEIGENSCHAFTEN聚合物连接
公开(公告)号：EP2875057A1
公开(公告)日：2015-05-27
申请号：EP13782829.9
申请日：2013-07-19
IPC分类号： C08F212/08 , C08F222/40 , C08F8/00 , C08F8/14
CPC分类号： B01D65/08 , B01D71/38 , B01D71/62 , B01D71/80 , B01D2321/168 , C08F8/00 , C08F8/14 , C08F212/08 , C08F2222/404 , C08F222/08
摘要： A polymer compound (I) with bacteria-adhesion inhibition properties against bacteria such as P.
aeruginosa Xen 5, E.
coli Xen 14, S.
typhimurium Xen 26, S.
aureus Xen 36 and K.
pneumoniae Xen 39 is described. The group R is provided by a substituted furanone linked by an alkyl chain or, more preferably a hydrophilic moiety such as oligo(ethylene oxide) ((CH
2 -CH
2 -O)
i ) to the polymer backbone. The group R may be the same or different along the polymer backbone. The invention also provides nanofibres and coatings which include a polymer compound as defined above.-
公开(公告)号：EP2864716A2
公开(公告)日：2015-04-29
申请号：EP13728528.4
申请日：2013-04-25
发明人： KRETZSCHMAR, Holger , GAUCHÉ, Paul
摘要： A central receiver for a solar power facility is provided comprising an arrangement of heat absorber tubes located in a chamber having a window that, in use, is to receive solar radiation reflected by a heliostat field. The heat absorber tubes extend transversely relative to the window and are connected into a working fluid circuit. The window forms an atmospheric air inlet and the chamber has an outlet in a region opposite the window. An air flow promoting fan induces a flow of atmospheric air inwards through the window, past the absorber tubes; and through the outlet. The receiver preferably includes multiple rows of unpressurized louvers or panes having oblique frontal surfaces such that reflected rays travel into the chamber and provide a leading row in which the temperature of the louvers is, under operating conditions, maintained at a level low enough to reduce thermal reflection and radiation losses.
摘要翻译： 提供了一种用于太阳能发电设施的中央接收器，其包括位于具有窗口的室中的吸热器的布置，所述窗口在使用中是接收由定日镜场反射的太阳辐射。 吸热器管相对于窗口横向延伸并连接到工作流体回路中。 窗口形成大气空气入口，并且室在与窗口相对的区域中具有出口。 气流促进风扇通过窗口向内引导大气空气流过吸收管; 并通过插座。 接收器优选地包括多排非加压百叶窗或具有倾斜前表面的窗玻璃，使得反射的光线进入室中并提供前行，其中百叶窗的温度在操作条件下保持在足够低的水平以降低热量 反射和辐射损失。
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公开(公告)号：EP2854621A1
公开(公告)日：2015-04-08
申请号：EP13736655.5
申请日：2013-05-29
IPC分类号： A61B5/00
CPC分类号： A61B5/4266 , A61B5/4875 , A61B5/6824 , A61B5/6833 , A61B10/0064
摘要： A sweat measuring device (1) comprising a sweat impermeable panel (40) and an adhesive skirt on one side thereof extending about its periphery to enable the panel to be secured to a user's skin is provided. The device covers a known area of a user's skin and traps sweat (42) produced by the skin under the panel. The panel (40) defines a reservoir in which sweat can accumulate and calibrations which may be associated with the reservoir to express the total sweat produced by the user as a function of the volume of sweat in the reservoir. The panel may be relatively stiff; formed by a plastics member and the skirt may extend integrally from the panel or be provided by an adhesive patch which covers the panel.
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公开(公告)号：EP2817323A1
公开(公告)日：2014-12-31
申请号：EP13717558.4
申请日：2013-02-22
摘要： Compositions containing one or more tyrocidines, tryptocidines, phenycidines and/or gramicidin S, or derivatives and analogues thereof, are described for controlling antimicrobial growth on plants, plant material or plant growth media, and methods for controlling or preventing the growth of microbial pathogens, and in particular fungal pathogens, on plants, plant parts and plant material are described herein. The active agents used to control these pathogens are tyrocidines, tryptocidines, phenycidines and/or gramicidin S, or derivatives, analogues or modifications thereof. The tyrocidines, tryptocidines, phenycidines and/or gramicidin S are cyclic decapeptides having the general amino acid sequence cyc/o(valine-Xrleucine-D-phenylalanine- proline-X
2 -X
3 -X
4 -X
5 -X
6 ) (SEQ ID NO: 1 ) or a derivative or analogue thereof, wherein X
1 is ornithine or lysine, X
2 is valine, leucine, isoleucine, phenylalanine, tryptophan or tyrosine; X
3 is the D-isomer of valine, leucine, isoleucine, phenylalanine, tryptophan, tyrosine, ornithine, or lysine; X
4 is asparagine, glutamine or leucine; X
5 is glutamine, the D-isomer of valine, leucine, or isoleucine; and X6 is tyrosine, phenylalanine, tryptophan or proline.
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