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91.发明公开
公开(公告)号：EP3858359A1
公开(公告)日：2021-08-04
申请号：EP19864600.2
申请日：2019-09-30
发明人： LEE, In Kyu , JEON, Jae Han , KANG, Hyeon-Ji
摘要： The present invention relates to a composition for prevention or treatment of hypercortisolemia, the composition comprising allithiamine, fursultiamine, and benfotiamine, which are all derivatives of thiamine, or a mixed composition thereof. The composition for prevention or treatment of hypercortisolemia of the present invention can effectively treat or alleviate symptoms or disorders resulting from excessive secretion of cortisol, without surgical operations, and does not exhibit side effects caused by conventional medications.
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92.发明公开
公开(公告)号：EP3845237A2
公开(公告)日：2021-07-07
申请号：EP20834993.6
申请日：2020-07-02
发明人： KIM, Jung Min , JIN, Jong Sook , KIM, Shukho
IPC分类号： A61K38/16 , A61P31/04 , A61P31/02 , A01N37/44 , A23L3/3526 , A23C9/152 , A23K20/147
摘要： The present invention relates to the use of the recombinant antibacterial protein Ablysin for effectively killing multidrug-resistant pathogenic bacteria. The recombinant protein Ablysin of the present invention exhibits apoptosis against antibiotic-resistant Acinetobacter baumannii, Klebsiella pneumoniae, Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus and Enterococcus faecium to prevent or treat infectious diseases caused by these bacteria and thus it can be widely used in antibiotics, disinfectants, food additives, feed additives, and the like. In particular, the Ablysin uses peptidoglycan, which is a component of the cell wall of bacteria, as a substrate, and exhibits bacterial killing ability due to peptidoglycan degradation. The peptidoglycan exists only in bacteria and not in humans or animals, and thus there is an advantage that Ablysin of the present invention is safe because it does not affect humans and animals, and can be applied to the pharmaceutical industry, food industry, biotechnology, etc., as well as can effectively kill bacteria in a target place or a target substance without problems of resistance to antimicrobial agents.
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公开(公告)号：EP3760691A1
公开(公告)日：2021-01-06
申请号：EP20191671.5
申请日：2017-04-14
发明人： KIM, Hong Joo , KIM, Sunghwan , PARK, Hwanbae , ROOH, Gul
摘要： This application relates to a scintillator and a preparation method therefor, wherein the scintillator comprises a matrix material including thallium, at least one alkaline earth metal element, and at least one halogen element.
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公开(公告)号：EP3127514B1
公开(公告)日：2020-11-25
申请号：EP15773253.8
申请日：2015-04-03
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公开(公告)号：EP3733111A1
公开(公告)日：2020-11-04
申请号：EP18897337.4
申请日：2018-12-20
发明人： PARK, Ilhyung , PARK, Chulwoo , LEE, Hyunwoo , JOUNG, Sanghyun , PARK, Youngkyun , YU, Jihun
IPC分类号： A61B90/00 , A61B6/00 , G06F3/0488
摘要： Provided is a laser projection apparatus, a control method thereof, and a laser guidance system including the laser projection apparatus. The laser projection apparatus for projecting planned operation information of an insertion location and an insertion angle on a C-arm image photographed using a C-arm fluoroscopy device directly onto an affected part includes a line laser module configured to generate a line laser and to form a plane by rotating around an origin, a matching unit configured to calculate a coordinate representing the insertion location in a C-arm coordinate system based on C-arm fluoroscopy, calculate an insertional vector according to the coordinate representing the insertion location and the insertion angle, and calculate a vector perpendicular to the plane formed by the line laser in the C-arm coordinate system according to the insertional vector, and a control unit configured to control the line laser module based on the vector perpendicular to the plane.
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公开(公告)号：EP3701891A1
公开(公告)日：2020-09-02
申请号：EP18871730.0
申请日：2018-10-22
发明人： PARK, Ilhyung , JOUNG, Sanghyun , PARK, Chulwoo , LEE, Hyunwoo , PARK, Youngkyun
摘要： This disclosure relates to an active retractor implemented to detect a stress state of a fractured area during fracture reposition and compensate for a required retracting force, and a control method thereof. The active retractor includes: a retracting shaft configured to fasten fractured bone fragments of a patient and retract the fractured bone fragments in a front and rear direction; a measuring device connected and installed to the retracting shaft to measure a retracting location or a retracting force of the retracting shaft; an actuator connected and installed to the retracting shaft to drive the retracting shaft in the front and rear direction; a driver configured to supply a power required for driving the actuator to the actuator according to a driving control signal; and a controller configured to generate a driving control signal, which is required for the driver to supply a power, by comparing a retracting request signal input from a user with a measured value transmitted from the measuring device and transmit the driving control signal to the driver.
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98.发明公开
公开(公告)号：EP3578651A2
公开(公告)日：2019-12-11
申请号：EP17882917.2
申请日：2017-12-26
发明人： LEE, Dong Woo , SHIN, Sun Mi , JOO, Yun Hye , SUNG, Jae Yoon
摘要： The present invention relates to a recombinant strain having a modified sugar metabolic pathway resulting from the introduction of an enzyme derived from a different strain to a strain, and a high-speed screening method for various mutants and variants by which useful materials can be obtained or which can produce useful materials. The use of a recombinant vector and a strain according to the present invention not only can construct a new metabolic pathway in a strain to effectively obtain D-tagatose from D-galactose, but also can introduce randomly modified sugar isomerases and then allow D-galactose isomerase variants to be rapidly screened by conducting a cell growth-associated screening system.
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公开(公告)号：EP3552567A1
公开(公告)日：2019-10-16
申请号：EP17879150.5
申请日：2017-12-08
申请人： Kyungpook National University Industry-Academic Cooperation Foundation , Daegu Gyeongbuk Institute of Science and Technology , Korea Advanced Institute of Science and Technology
发明人： KIM, Shin Yoon , KIM, Jun Young , SEO, Anna , LEE, Hee Sung , HWANG, Jae Youn , YOUN, Sang Yeon , CHOI, Jae Suk , JE, Min Kyu
摘要： A smart screw according to an embodiment may comprise: a screw main body which penetrates an artificial joint including a shell disposed on a hip joint of an object and a liner disposed on the inner surface of the shell and is then inserted into the hip joint; a transducer including a coupling layer that senses a sound wave signal reflected from the liner, a piezo-electric layer formed to determine a frequency of the sound wave signal, and a sound absorbing layer for absorbing the sound wave signal; and a processing module for generating a sound wave signal toward the liner and receiving the sound wave signal sensed by the coupling layer, measuring the thickness of the liner on the basis of the received sound wave signal, and transferring data about the measured thickness of the liner to the outside.
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公开(公告)号：EP3499464A1
公开(公告)日：2019-06-19
申请号：EP17839799.8
申请日：2017-08-09
申请人： Koh Young Technology Inc. , Kyungpook National University Industry-Academic Cooperation Foundation
发明人： KWON, Ki Hoon , KIM, Min Young
摘要： A method and a device for registering three-dimensional data are disclosed. The method for registering three-dimensional data comprises: generating first two-dimensional data by two-dimensionally converting first three-dimensional data indicating a surface of a three-dimensional model of a target, generating second two-dimensional data by two-dimensionally converting second three-dimensional data indicating at least a part of the three-dimensional surface of the target; determining a first matching region in the first two-dimensional data and a second matching region in the second two-dimensional data by matching the second two-dimensional data to the first two-dimensional data; setting, as initial position, a plurality of points of the first three-dimensional data, which correspond to the first matching region and a plurality of points of the second three-dimensional data, which correspond to the second matching region; and registering the first three-dimensional data and the second three-dimensional data using the initial position.
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